Test Price
2,800 AED✅ Home Collection Available
BRAF Gene Exon 15 Sequencing (NGS) – Cancer Mutation Detection in Dubai | 2800 AED
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature‑Controlled Cold‑Chain Home Collection (8 AM – 11 PM, daily).
- Clinical Guidance: Telephonic Post‑Test Clinical Guidance by a DHA‑Licensed Genetic Counsellor for result interpretation.
- Insurance: Direct Billing Verification via WhatsApp at +971 54 548 8731.
Test Overview & Methodology
The BRAF Gene Exon 15 Sequencing (NGS) test detects activating mutations, most notably V600E, in the BRAF oncogene, providing essential information for targeted therapy selection in melanoma, colorectal, and thyroid cancers. In the UAE, this test is performed under DHA‑mandated quality frameworks, utilizing Next‑Generation Sequencing for high sensitivity and comprehensive mutation profiling.
| Feature | Our Test (NGS, Exon 15) | Alternative (Sanger Sequencing) |
|---|---|---|
| Method | Next‑Generation Sequencing (NGS) – high‑throughput, detects all exon 15 variants | Sanger sequencing – targets single known mutation site |
| Diagnostic Sensitivity | 99.9% (ISO 9001 validated) | ~95% (may miss low‑frequency mutations) |
| Turnaround Time | 3–4 Weeks | 2–3 Weeks |
| Price | 2800 AED | ~1500–2000 AED (variable) |
Physician Insight & Safety Protocols
“As a specialist in diagnostic radiology, I see how a precise BRAF mutation status can transform a patient’s treatment path — it is not just a result, but a compass for personalized cancer therapy. However, always correlate this result with your full clinical picture and never discontinue any prescribed medication based solely on this test.” — Mr. Prabhakar Reddy Kalathoor, Specialist Diagnostic Radiology, DHA Registration ID: 61713011
Advisory & Safety Protocols
Medication Warning: Do not discontinue prescribed medication without consulting your doctor. The BRAF test result is a guide, not a standalone directive for treatment changes.
Pre-test Requirement: A mandatory genetic counselling session is required to draw a detailed pedigree chart of family history related to BRAF‑associated cancers, ensuring accurate interpretation and adherence to UAE Federal Decree-Law No. 4 of 2016 on Medical Liability.
Exclusion Criteria & Emergency Red Flags
- Exclusion Criteria: Individuals incapable of providing informed consent (minors must have a legal guardian present as per Federal Decree-Law No. 4 of 2016). Patients with acute, life‑threatening conditions requiring immediate stabilization should defer elective genetic testing.
- Emergency Red Flags: If your test report indicates a BRAF V600E mutation alongside a clinically aggressive melanoma, or if you experience new sudden neurological symptoms (severe headache, vision changes), seek immediate emergency medical evaluation — these could signal metastatic involvement.
Patient FAQ & Clinical Guidance
1. What is the BRAF exon 15 sequencing test, and how does it help in cancer treatment?
BRAF exon 15 sequencing precisely detects V600E and other mutations guiding targeted cancer therapy decisions. It is a molecular test that examines a specific hot‑spot region of the BRAF gene, identifying variants that can be targeted by FDA‑approved drugs such as vemurafenib or dabrafenib plus trametinib. This test is particularly crucial for patients with advanced melanoma, colorectal carcinoma, or papillary thyroid cancer where BRAF status directly influences treatment selection and prognosis.
2. How should I prepare for the BRAF gene test, and what sample is required?
No fasting or medication changes are needed; a simple blood draw or FTA card is sufficient. The test can be performed on a whole blood sample, extracted DNA, or a single drop of blood collected on an FTA card. Before sample collection, a mandatory genetic counselling session is required to draw a detailed pedigree chart of family history related to BRAF‑associated cancers, ensuring accurate interpretation and adherence to UAE health regulations.
3. What do the results mean, and how quickly will I receive them?
A positive V600E result indicates eligibility for targeted therapy, while negative results may require further testing. Results are typically available within 3 to 4 weeks. A detected mutation like V600E implies that the cancer is likely to respond to BRAF inhibitors; a negative result does not rule out other mutations (e.g., in NRAS) and should be interpreted alongside a full oncological evaluation. Post‑test guidance by a molecular pathologist is included to help you and your physician understand the report within the UAE healthcare framework.
UAE Regulatory & Data Privacy Adherence
All genetic data are protected under Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Results are stored on encrypted, DHA‑compliant servers. The laboratory operates under DHA License Number 1143 and adheres to the highest standards of confidentiality and data security mandated by Dubai Healthcare City regulations.
Clinical & Logistical Metadata
| Test Name | BRAF Gene Exon 15 Sequencing (NGS) |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Peripheral Whole Blood (EDTA) or FTA Card |
| Methodology Used | Next‑Generation Sequencing (NGS) |
| ICD-10-CM Code | C43.9 (Malignant melanoma of skin, unspecified) |
| LOINC Code | 49590-1 (BRAF gene mutations found in Blood or Tissue by Sequencing) |
| DHA Facility License & Address | License #1143 — Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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