Test Price
2,800 AEDโ Home Collection Available
ALK Gene (Neuroblastoma Type 3, Familial) Susceptibility NGS Test in UAE | 2,800 AED
Executive Summary & Core Metrics
Executive Summary
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139).
- Biocompatible Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
- Clinical Guidance: Telephonic Post-Test Clinical Interpretation Support by DHA-licensed genetics specialists.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
Test Overview
This advanced Next-Generation Sequencing test screens the full coding region of the ALK gene to detect hereditary mutations linked to familial neuroblastoma type 3, providing critical risk stratification for children and guiding early surveillance protocols.
Methodology: Next-Generation Sequencing (NGS)
The assay uses targeted NGS with full coverage of all coding exons and splice junctions, achieving 99.9% sensitivity for single nucleotide variants and small insertions/deletions in the associated region.
| Feature | Our NGS Test | Closest Alternative |
|---|---|---|
| Precision | Full gene NGS with 99.9% sensitivity | Sanger sequencing โ limited to known hotspots |
| Methodology | NGS (Next-Generation Sequencing) | Traditional single-exon analysis |
| Turnaround Time | 12 Business Days | 6 โ 8 Weeks |
| Sample Type | Whole Blood, Extracted DNA, or Fingerpick FTA Card | Blood only |
Physician Insight & Safety Protocols
โThis test provides powerful early insight into hereditary neuroblastoma risk, but a negative result does not eliminate clinical surveillance. Genetic counselling must precede testing and guide result interpretation. Decisions about prophylactic interventions require collaboration with a pediatric oncologist.โ
โ Lina Osama Zaki Quteineh | Consultant Medical Genetics | DHA Registration ID: 9294403
Safety Advisory
Medication Advisory
Do not stop or alter prescribed medications without consulting your treating physician. This genetic risk assessment does not replace ongoing clinical management or emergency care.
Exclusion Criteria & Red Flags
- Exclusion: Individuals without documented family history of neuroblastoma or known ALK-related syndromes; the test may not detect non-coding regulatory variants.
- Exclusion: Children under 5 years of age without a clear clinical indication or prior genetic counselling session. A mandatory pre-test counseling session is required.
- Red Flag โ Seek Immediate Emergency Care If: Sudden limb weakness, severe headaches, uncontrolled eye movements, or rapid abdominal distension develop in the patient. Do not wait for genetic results to seek urgent medical attention.
Patient FAQ & Clinical Guidance
1. What does the ALK gene detect and who should consider it?
Key Answer: It detects inherited pathogenic variants in the ALK gene that cause familial neuroblastoma type 3. It is recommended for families with early-onset tumors, multiple affected relatives, or a known syndrome. Genetic counselling is mandatory prior to testing.
2. How does the home collection service work?
Key Answer: A DHA-licensed phlebotomist arrives at your home (8 AMโ11 PM) with an ISO-certified cold-chain kit. Options include standard blood draw, pre-extracted DNA, or a simple finger-prick on an FTA card. Chain of custody is maintained throughout.
3. What happens after I receive my results?
Key Answer: A telephonic consultation with a DHA-certified genetics specialist explains clinical implications. All genetic data is stored in compliance with UAE PDPL and Federal Law No. 2 of 2019 concerning use of ICT in health fields. You retain full rights over your personal data.
UAE Regulatory & Data Privacy Adherence
Data Protection & Regulatory Compliance
- Privacy Framework: Compliant with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL).
- Health Data Use: Adheres to Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields.
- Medical Liability: All clinical testing and patient consent procedures follow Federal Decree-Law No. 4 of 2016 on Medical Liability.
Clinical & Logistical Metadata
| Test Name | ALK Gene (Neuroblastoma Type 3, Familial) Susceptibility NGS Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 12 Business Days |
| Sample Type / Matrix | Whole Blood, Extracted DNA, or Fingerpick FTA Card |
| Methodology Used | Next-Generation Sequencing (NGS), full gene coverage |
| ICD-10-CM Code | C74.91, Z80.6 |
| LOINC Code | 74057-6, 91822-4 |
| DHA Facility License & Laboratory Address | License No: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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