Test Price
220 AED✅ Home Collection Available
Smooth Muscle Antibody (ASMA) Serology Test in UAE | AED 220 | DNA Labs UAE
Executive Summary & Core Metrics
DNA Labs UAE offers the gold-standard Immunofluorescence Assay (IFA) for Smooth Muscle Antibody (ASMA) serology, a critical biomarker for diagnosing Autoimmune Hepatitis Type 1. Our DHA-licensed facility (License 1143) ensures 99.9% diagnostic sensitivity through ISO 9001:2015 accredited processes, providing same-day results for early clinical intervention.
Test Overview & Methodology
The Smooth Muscle Antibody (ASMA) test, also known as anti‑actin or anti‑smooth muscle antibody, detects autoantibodies targeting smooth muscle actin, a key serological marker for autoimmune hepatitis (type 1). It is primarily ordered by Gastroenterologists, Hepatologists, and Clinical Immunologists to differentiate autoimmune liver disease from viral or toxic hepatitis, often alongside ANA and LKM-1 panels.
| Feature | Our Test (IFA Gold Standard) | Closest Alternative (ELISA) |
|---|---|---|
| Methodology | Immunofluorescence Assay (IFA) on rodent tissue substrate | Enzyme‑Linked Immunosorbent Assay (anti‑actin IgG) |
| Sensitivity | ≥95% (confirms pattern specificity) | ~85–90% (may miss atypical patterns) |
| Turnaround | Same day (if sample received by 9 AM) | 24–48 hours |
| Reimbursement | Direct insurance billing supported | Often out‑of‑pocket |
Physician Insight & Safety Protocols
Clinical Correlation Note from Dr. Ajay Singh (DHA License: 36234132):
“In my clinical practice, a positive ASMA result serves as a key serological cornerstone for diagnosing autoimmune hepatitis type 1. It is imperative to correlate this finding with liver function tests and IgG levels. At DNA Labs UAE, our integrated approach ensures patients receive comprehensive support from sample collection to result interpretation.”
Medication & Safety Advisory
Do not discontinue prescribed corticosteroids, azathioprine, or any other immunosuppressant without explicit instruction from your treating physician. Abrupt cessation may trigger a life‑threatening autoimmune flare.
Exclusion Criteria & ER Red Flags
- Absolute contraindications to venipuncture (e.g., severe hemophilia A with unmodified coagulation, active bloodstream infection).
- Known allergy to latex or chlorhexidine (alternative phlebotomy kit available).
- Red Flags: Sudden onset of jaundice, severe right upper quadrant pain, ascites, or confusion — seek emergency care immediately; these may indicate acute liver failure independent of ASMA status.
- Minors: In compliance with Federal Decree-Law No. 4 of 2016 on Medical Liability, guardians must provide explicit consent; pediatric samples require smaller volume (1 mL serum).
Patient FAQ & Clinical Guidance
1. What is the purpose of the Smooth Muscle Antibody (ASMA) test?
This test detects autoantibodies directed against smooth muscle actin, providing strong serological support for confirming a diagnosis of Autoimmune Hepatitis Type 1. An elevated ASMA titer (≥1:40) is a powerful vital indicator, provided other causes of elevated liver enzymes are excluded.
2. How is the ASMA test performed, and why is fasting required?
A venous blood sample is drawn after overnight fasting to avoid lipemic interference that can obscure the immunofluorescence pattern. The serum is then incubated on a tissue substrate, and a specialist pathologist interprets the characteristic smooth muscle staining pattern under a fluorescence microscope.
3. What does a positive ASMA test result indicate?
A positive result (titer ≥1:40) strongly suggests Autoimmune Hepatitis Type 1, but it must be interpreted alongside liver function tests and other serological markers such as ANA and IgG. Follow-up with a hepatologist or gastroenterologist is essential to establish an appropriate treatment plan.
UAE Regulatory & Data Privacy Adherence
DNA Labs UAE strictly adheres to Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All patient data is encrypted and processed with the highest level of confidentiality. Clinical safety and patient consent protocols are governed by Federal Decree-Law No. 4 of 2016 on Medical Liability. Our laboratory is ISO 9001:2015 certified (Certification ID: INT/EGQ/2509DA/3139).
Clinical & Logistical Metadata
| Test Name | Smooth Muscle Antibody (ASMA) Serology |
| Price (AED) | 220 |
| Turnaround Time | Same Day (if sample received by 9 AM) |
| Sample Type / Matrix | Serum (VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily 8 AM – 11 PM) |
| Methodology Used | Immunofluorescence Assay (IFA) on rodent tissue substrate |
| ICD-10-CM Code | K75.4 (Autoimmune hepatitis), K73.2 (Chronic active hepatitis, not elsewhere classified), Z15.89 (Genetic susceptibility to other specified disease) |
| LOINC Code | 16108-8 (Smooth muscle Ab [Titer] in Serum by Immunofluorescence) |
| DHA Facility License & Laboratory Address | License 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians