Test Price
600 AED✅ Home Collection Available
Anti‑Nuclear Antibody (ANA) / Anti‑Nuclear Factor (ANF) by IFA (HEp‑2) with Reflex to ENA Profile in UAE | 600 AED
Executive Summary & Core Metrics
Core Metrics
- Diagnostic Sensitivity: Exceeding 99.9% for ANA detection on HEp‑2 IFA, with automatic reflex to ENA immunoblot for positive results.
- Accreditation: ISO 9001:2015 certified (Cert: INT/EGQ/2509DA/3139) processing ensures standardized quality.
- Logistics: VIP mobile phlebotomy with temperature-controlled cold-chain transport, available 8 AM – 11 PM daily.
- Clinical Support: Complimentary post-test telephone interpretation with a DHA-licensed general practitioner.
- Insurance: Direct billing verification via WhatsApp at +971 54 548 8731.
Test Overview & Methodology
The Anti‑Nuclear Antibody (ANA) / Anti‑Nuclear Factor (ANF) by Indirect Immunofluorescence Assay (IFA) on HEp‑2 cells with reflex to Extractable Nuclear Antigen (ENA) profile is the gold‑standard screening tool for autoimmune connective tissue diseases. A positive ANA pattern triggers automatic immunoblot confirmation for specific ENA autoantibodies (e.g., anti‑dsDNA, anti‑Ro, anti‑La, anti‑RNP, anti‑Sm, anti‑Scl‑70), enabling precise rheumatologic diagnosis within one unified workflow.
| Feature | Our Test (DHA‑Compliant) | Closest Alternative |
|---|---|---|
| Methodology | IFA on HEp‑2 substrate (titer + pattern) with reflex immunoblot for ENA profile | Standalone ANA ELISA (no pattern/titer) |
| Clinical Precision | 99.9% sensitivity; identifies subset auto‑antibodies for SLE, Sjögren’s, MCTD | Limited specificity, often requires retesting |
| Turnaround / Reflex | Report next working day; automatic ENA reflex eliminates second sample collection | Manual add‑on, delayed diagnosis |
Physician Insight & Safety Protocols
“A positive ANA is not a diagnosis; it is a laboratory finding that requires correlation with the patient’s clinical presentation, titer, HEp‑2 pattern, and full ENA panel. Always interpret these results together with a thorough history and physical exam. Never alter or discontinue prescribed medications without consulting your treating physician.” — Dr. Ajay Singh, General Practitioner, DHA License No. 36234132
Medication Advisory
Important: Do not stop, start, or change any medication, including hydroxychloroquine, corticosteroids, or immunosuppressants, based solely on this test result. Any therapeutic adjustment must be supervised by your treating physician to avoid disease flares or adverse effects.
Exclusion Criteria & Red Flags
- Active febrile illness or acute infection — postpone blood draw until afebrile for 48 hours.
- Known severe haemodynamic instability — seek immediate medical attention.
- Emergency signs: pleuritic chest pain, sudden vision loss, major organ thrombosis, or acute renal impairment; proceed to the nearest emergency department immediately.
Patient FAQ & Clinical Guidance
1. What is the ANA/ANF HEp‑2 IFA with reflex test and why is it preferred?
The ANA/ANF test using IFA on HEp‑2 cells is the gold standard for screening autoimmune connective tissue diseases because it detects the full spectrum of nuclear and cytoplasmic autoantibodies with pattern recognition. When positive, an automatic reflex to the ENA immunoblot identifies specific antibodies (e.g., anti‑dsDNA, anti‑Ro, anti‑La) without requiring a second blood draw, enabling rapid diagnosis.
2. How should I prepare for the blood test and when will I receive results?
Overnight fasting is preferred but not mandatory. A single 2 mL serum sample in a standard SST tube is sufficient. Specimens are processed Monday to Saturday until 11 AM, and the final report including any reflex testing is delivered the next working day.
3. Is this test covered by UAE insurance and can home collection be arranged?
Most UAE insurance plans support direct billing; send your Emirates ID and policy details via WhatsApp for verification. Our DHA‑licensed mobile phlebotomists provide home collection from 8 AM to 11 PM daily, with temperature‑controlled transport ensuring sample integrity.
UAE Regulatory & Data Privacy Adherence
Data Protection & Health Information Governance: All patient data is processed in compliance with Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and patient consent adhere to Federal Decree‑Law No. 4 of 2016 on Medical Liability. Your test results are handled with strict confidentiality and stored on secure, UAE‑based servers.
Clinical & Logistical Metadata
| Test Name | Anti‑Nuclear Antibody (ANA) / Anti‑Nuclear Factor (ANF) by IFA (HEp‑2) with Reflex to ENA Profile |
| Price (AED) | 600 AED |
| Turnaround Time | Next working day (including reflex testing) |
| Sample Type / Matrix | Serum (2 mL SST) |
| Methodology Used | Indirect Immunofluorescence Assay (IFA) on HEp‑2 cells with immunoblot reflex for ENA profile |
| ICD-10-CM Code | R76.9 (Abnormal immunological finding in serum) |
| LOINC Code | 43188-8 (ANA IFA pattern and titer) |
| DHA Facility License & Laboratory Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE (DNA Labs UAE) |
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