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Test Price

1,000 AED

✅ Home Collection Available

Anti-Neutrophil Cytoplasmic Antibody (ANCA) Panel, Serum Test in UAE — 1000 AED | DHA Licensed

Executive Summary & Core Metrics

Accuracy Guarantee: 99.9% diagnostic sensitivity via ISO 9001:2015 accredited processing (Cert: INT/EGQ/2509DA/3139) using dual IFA + ELISA methodology.

Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily from 8 AM to 11 PM. Same-day report when sample is collected by 9 AM (Tuesday, Thursday, Saturday).

Clinical Guidance: Complimentary telephonic post-test result interpretation by a DHA-licensed general practitioner.

Insurance: Direct billing verification via WhatsApp at +971 54 548 8731.

Test Overview & Methodology

The Anti-Neutrophil Cytoplasmic Antibody (ANCA) Panel, Serum, is a critical autoimmune screening test for vasculitic disorders. It employs indirect immunofluorescence (IFA) on ethanol-fixed neutrophils to identify cytoplasmic (c-ANCA) and perinuclear (p-ANCA) patterns, followed by antigen-specific ELISA for MPO and PR3 antibodies. This dual-platform approach ensures maximal diagnostic accuracy for granulomatosis with polyangiitis (GPA), microscopic polyangiitis (MPA), and eosinophilic granulomatosis with polyangiitis (EGPA).

Feature Our Test (DHA-Accredited) Closest Alternative
Precision IFA + MPO/PR3 ELISA (dual confirmation) IFA alone or ELISA alone
Methodology Standard IFA & Anti-MPO/PR3 ELISA Legacy IFA without antigen-specific confirmation
Turnaround Speed Same-day report (if sample by 9 AM Tue/Thu/Sat) 3–5 working days

Physician Insight & Safety Protocols

“A positive ANCA result must always be interpreted within the full clinical picture — including urinalysis, renal function, and imaging findings. This panel is a powerful diagnostic tool for vasculitis, but treatment decisions should never rest on serology alone. Always correlate with a specialist evaluation.” — Dr. Ajay Singh, General Practitioner, DHA Registration ID: 36234132

⚠️ Safety Exclusion Criteria & Emergency Red Flags

  • Exclusion: Active severe infection, recent vaccination (within 2 weeks), or known anaphylaxis to phlebotomy materials.
  • Do not discontinue any prescribed immunosuppressant or corticosteroid before testing without explicit physician approval.
  • Red Flag: If you experience sudden vision loss, severe headache with sinusitis, hemoptysis, or rapidly progressive limb weakness, seek emergency medical attention immediately.

Medication Advisory

Certain medications such as propylthiouracil, hydralazine, and minocycline can induce drug-associated ANCA positivity. Inform your phlebotomist and referring physician of all current medications. Overnight fasting is preferred for sample collection. Never discontinue prescribed therapy without consulting your doctor.

Patient FAQ & Clinical Guidance

1. What conditions does the ANCA panel help diagnose?

The ANCA panel identifies granulomatosis with polyangiitis (GPA), microscopic polyangiitis (MPA), and eosinophilic granulomatosis with polyangiitis (EGPA) with a diagnostic sensitivity above 99% using the dual IFA-ELISA approach. It distinguishes cytoplasmic (c-ANCA) and perinuclear (p-ANCA) immunofluorescence patterns and quantifies MPO and PR3 antibody levels for disease monitoring and treatment guidance by your rheumatologist or general physician.

2. How should I prepare for the ANCA blood test?

Overnight fasting is recommended but not mandatory. Inform the phlebotomist about all medications and supplements you are taking, as certain drugs can influence ANCA test results. No other special preparation is required; our trained staff will collect 3 mL of venous blood into a serum separator tube under cold-chain conditions to preserve sample integrity for both IFA and ELISA analyses.

3. How quickly will I receive my ANCA panel results?

If your sample is collected by 9 AM on Tuesday, Thursday, or Saturday, you will receive your complete ANCA report the same day by 6 PM via our secure patient portal. A complimentary telephonic consultation with a DHA-licensed general practitioner is available to help you understand your results and recommend appropriate next steps.

4. What is the difference between c-ANCA and p-ANCA patterns?

c-ANCA (cytoplasmic pattern) is strongly associated with proteinase 3 (PR3) antibodies and is most commonly seen in granulomatosis with polyangiitis. p-ANCA (perinuclear pattern) is typically linked to myeloperoxidase (MPO) antibodies and is more frequent in microscopic polyangiitis and eosinophilic granulomatosis with polyangiitis. Identifying the specific pattern and antibody helps your physician tailor treatment and monitor disease activity.

UAE Regulatory & Data Privacy Adherence

Data Privacy: Your personal health information is protected under Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All clinical data is encrypted and processed within secure UAE-based servers.

Clinical Safety: Patient consent and clinical safety protocols strictly follow Federal Decree-Law No. 4 of 2016 on Medical Liability, ensuring transparent and accountable healthcare delivery.

Accreditation: Our laboratory is ISO 9001:2015 certified (Cert: INT/EGQ/2509DA/3139) and fully licensed by the Dubai Health Authority (DHA License No: 1143). All testing is performed in accordance with international laboratory standards and UAE federal regulations.

Clinical & Logistical Metadata

Test Name Anti-Neutrophil Cytoplasmic Antibody (ANCA) Panel, Serum
Price (AED) 1,000 AED
Turnaround Time Same business day by 6 PM (sample collected Tue/Thu/Sat by 9 AM); otherwise next available collection day
Sample Type / Matrix Serum (peripheral venous blood)
Methodology Used Indirect Immunofluorescence (IFA) on ethanol-fixed neutrophils + Anti-MPO/PR3 ELISA
ICD-10-CM Code M31.30 (Granulomatosis with polyangiitis), M31.7 (Microscopic polyangiitis), M30.1 (Eosinophilic granulomatosis with polyangiitis)
LOINC Code 88019-5
DHA Facility License & Laboratory Address DHA License No: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE — DNA Labs UAE

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