Test Price
2,800 AED✅ Home Collection Available
SETX Gene Amyotrophic Lateral Sclerosis Type 4 Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل الجين SETX لمرض التصلب الجانبي الضموري النوع 4 في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Executive Summary | الملخص التنفيذي
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Certified Processing (Cert: INT/EGQ/2509DA/3139).
- Premium Logistics: Paid Hospital-Grade Home Collection via ISO-Certified Cold-Chain Home Collection; VIP Mobile Phlebotomy available 8 AM–11 PM.
- Clinical Guidance: Complimentary telephonic post‑test clinical guidance for result interpretation by DHA‑licensed neurologists.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731; we handle prior approval with major UAE insurers.
يقدم اختبار تسلسل الجينوم من الجيل التالي (NGS) لجين SETX دقة تشخيصية تصل إلى 99.9% وفقًا لمعايير الآيزو 9001:2015. يشمل الخدمة سحب عينات منزلية متميزة مع استشارة ما بعد الفحص. تتوفر الموافقة المباشرة للتأمين عبر واتساب على الرقم 971545488731+.
Overview
The SETX Gene NGS Test identifies pathogenic variants in the senataxin gene associated with ALS Type 4 (juvenile-onsetslow‑progressing ALS), enabling precise diagnosis, prognosis assessment, and informed family planning. This analysis uses next-generation sequencing (NGS) with 99.9% sensitivity, performed in our ISO 9001:2015‑certified diagnostic laboratory in Dubai, UAE.
| Feature | Our NGS SETX Test | Sanger Sequencing (Closest Alternative) |
|---|---|---|
| Method | Next‑Generation Sequencing (NGS) | Sanger Sequencing (targeted) |
| Coverage | Full coding exons ±20 bp flanking regions | Hotspot regions only; may miss novel variants |
| Sensitivity | >99.9% for single nucleotide variants & small indels | >99.5% for targeted sites; cannot detect large rearrangements |
| Turnaround Time | 3–4 Weeks | 2–3 Weeks |
| Clinical Utility | Comprehensive; enables carrier testing & family screening | Limited to known familial mutation follow‑up |
| Price (AED) | 2,800 | 1,800–2,200 |
Physician Insight & Safety Protocol
“As a DHA‑licensed Neurologist, I urge you to remember that a genetic test is a powerful tool, not a standalone verdict. A positive SETX mutation supports a diagnosis of ALS type 4, but it must be interpreted alongside your clinical picture and family history. Your treatment plan should be guided by a specialist; genetic results are one piece of the diagnostic puzzle.”
— Dr. PRABHAKAR REDDY, DHA License 61713011
⚠️ Medication Warning:
Do not discontinue prescribed medication or alter your treatment based solely on this test result. Always consult your managing physician before making any changes.
Safety Information & Exclusion Criteria
- Not suitable for patients with acute febrile illness or severe anaemia (Hb <8 g/dL) that may compromise sample quality.
- Minors must be accompanied by a legal guardian; parental consent is mandatory per UAE CDS Law 2026.
- Individuals unable to understand and provide informed consent must have a legally authorised representative.
- Emergency Red Flags: If you experience sudden limb weakness, difficulty breathing, choking, or rapid worsening of symptoms, do not wait for test results — seek emergency medical care immediately.
Pre‑Test Essentials
A pre‑test genetic counselling session is mandatory. Our genetic counsellors will draw a detailed three‑generation pedigree chart, review your clinical history, and explain possible outcomes, ensuring fully informed consent. No fasting is required for blood draw. Sample options: 2 mL of whole blood (EDTA tube), extracted DNA (≥1 µg), or a dried blood spot (one drop on FTA card).
Patient FAQ & Clinical Guidance
1. What is the SETX Gene ALS Type 4 NGS Test used for?
Snippet answer: This test detects mutations in the senataxin gene responsible for juvenile-onset amyotrophic lateral sclerosis type 4, aiding definitive diagnosis, prognosis, and family risk assessment. Further: It is recommended for individuals with early‑onset, slowly progressive motor neuron disease or a family history of ALS. A positive result confirms the genetic subtype and may guide targeted research or future therapies. We use full‑gene sequencing to identify both known and novel variants. If you are asymptomatic but have a family mutation, this test can determine carrier status.
السؤال: ما هو اختبار تسلسل الجين SETX للكشف عن التصلب الجانبي الضموري النوع 4؟
الإجابة: يكشف هذا الاختبار عن الطفرات في جين السيناتاكسين المسؤول عن الشكل اليفعي من التصلب الجانبي الضموري النوع 4، مما يساعد في التشخيص الدقيق وتقييم خطورة المرض والتخطيط العائلي.
2. How is the test performed and what sample is required?
Snippet answer: A simple blood draw, extracted DNA sample, or a single drop of dried blood on an FTA card is collected by a certified phlebotomist at your home or our clinic. The sample is transported under strict cold‑chain conditions to our ISO‑certified laboratory. Sequencing is performed using NGS, and results are interpreted by board‑certified clinical geneticists. Turnaround time is 3 to 4 weeks. You need to complete a pre‑test genetic counselling session to ensure appropriate sample selection and documentation.
السؤال: كيف يتم إجراء الاختبار وما نوع العينة المطلوبة؟
الإجابة: يمكن جمع عينة دم وريدي بسيطة أو عينة من الحمض النووي المستخلص أو قطرة دم جافة على بطاقة FTA عبر ممرض متخصص في المنزل أو في العيادة، مع الالتزام بسلسلة التبريد المعتمدة.
3. Can this be used for asymptomatic family members?
Snippet answer: Yes, once a disease‑causing mutation is identified in the family, asymptomatic relatives can be tested to clarify carrier status and reproductive risks. Predictive testing requires extensive counselling and strict adherence to UAE PDPL data privacy regulations. For minors, testing is only permitted with parental consent and a clear clinical benefit, in line with CDS Law 2026. Our genetic counsellors will guide you through the ethical and psychological considerations before any sample is taken.
السؤال: هل يمكن إجراء هذا الاختبار لأفراد العائلة غير المصابين بأعراض؟
الإجابة: نعم، بعد تحديد الطفرة المسببة للمرض في العائلة، يمكن فحص الأقارب غير المصابين لتحديد ما إذا كانوا حاملين للطفرة وتقييم المخاطر الإنجابية، مع الالتزام بقوانين حماية البيانات الشخصية.
✅ Licensed by Dubai Health Authority (DHA) – Facility License: 9834453
✅ Certified: ISO 9001:2015 (Cert: INT/EGQ/2509DA/3139)
✅ Compliant with Federal Decree‑Law No. 41 of 2024 on Medical Liability (Art. 87), UAE CDS Law 2026 (child data protection & consent), and UAE Personal Data Protection Law (PDPL).
✅ Primary Specialists Involved: Neurologist, Clinical Geneticist, Genetic Counsellor
*Price is indicative and may vary based on sample type and insurance coverage. Always consult a qualified healthcare professional for personal medical advice.
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Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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All reports reviewed by DHA-Certified physicians