Test Price
2,800 AED✅ Home Collection Available
CHGB Gene ALS Risk Factor Genetic Test in UAE | 2800 AED | DHA Licensed
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited NGS Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation by certified specialists.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The CHGB (Chromogranin B) gene NGS test screens for pathogenic variants linked to increased susceptibility to Amyotrophic Lateral Sclerosis (ALS). This advanced genetic analysis, performed via Next Generation Sequencing, provides critical insights for neurological risk assessment and family planning.
| Feature | Our Test (NGS) | Alternative (Sanger Sequencing) |
|---|---|---|
| Precision | 100% coding region coverage, 99.9% analytical sensitivity | ~98% coverage, lower variant detection rate |
| Method | Next Generation Sequencing (NGS) | Capillary Sanger Sequencing |
| Speed | 3–4 weeks | 6–8 weeks |
| Validation | ISO 9001:2015 accredited, DHA-compliant | Research-grade only |
Physician Insight & Safety Protocols
"Genetic testing for ALS risk must be interpreted within the broader clinical picture, including family history and symptom onset. A positive result suggests increased susceptibility, not a definitive diagnosis, and should prompt specialist monitoring. I strongly recommend discussing all findings with your neurologist or genetic counsellor."
Medication Advisory
Do not discontinue any prescribed medication without consulting your doctor. Genetic results are not a substitute for ongoing medical management.
Safety: Exclusion Criteria & Emergency Red Flags
- Exclusion: Known non-ALS genetic syndromes, inability to provide informed consent, minors without legal guardian consent.
- Exclusion: Active severe coagulopathy or inability to collect blood sample via aseptic technique.
- ER Red Flags: Rapidly progressing muscle weakness, difficulty breathing or swallowing, sudden speech loss – seek immediate emergency care.
Patient FAQ & Clinical Guidance
1. What is the CHGB gene test for ALS risk?
Answer: The CHGB gene test analyzes your DNA for mutations that raise your lifetime risk of Amyotrophic Lateral Sclerosis using high-throughput NGS technology. This test targets the full coding sequence of the Chromogranin B gene, which plays a role in neuronal secretion; variants here have been associated with familial and sporadic ALS susceptibility. A positive result indicates a higher risk but not certainty of developing the disease, and results are best interpreted with genetic counselling.
2. How accurate is this ALS genetic test and how does it compare to other methods?
Answer: With ISO 9001:2015 accredited NGS at 99.9% analytical sensitivity, our test far exceeds the reliability of single‑gene Sanger sequencing in detecting CHGB variants. NGS simultaneously reads millions of DNA fragments, delivering deep coverage of the entire gene with variant allele frequencies as low as 5%, while traditional methods often miss low‑level mosaicism. The laboratory follows DHA guidelines and UAE PDPL, ensuring your genetic data is securely handled and clinically actionable.
3. What should I expect after receiving the test results?
Answer: After receiving your CHGB NGS report, a specialist neurologist or genetic counsellor will provide a telephonic clinical guidance session to explain your result. You will learn whether a pathogenic variant was found, its possible implications for your health and family, and receive recommendations for follow‑up with a neurologist. If no variant is detected, your ALS risk from CHGB remains low, but genetic counselling may still address family history. We also support insurance direct billing via WhatsApp.
UAE Regulatory & Data Privacy Adherence
Compliance Framework
This genetic test is performed under DHA Facility License Number 1143 and adheres to Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All clinical safety and patient consent protocols follow Federal Decree-Law No. 4 of 2016 on Medical Liability. Samples are processed in ISO 9001:2015 accredited laboratories. Data privacy and informed consent are strictly maintained.
Clinical & Logistical Metadata
| Test Name | CHGB Gene ALS Risk Factor Genetic Test (NGS) |
| Price (AED) | 2,800 |
| Turnaround Time | 21–28 Business Days |
| Sample Type / Matrix | Peripheral Whole Blood |
| Methodology Used | Next Generation Sequencing (NGS) |
| ICD-10-CM Code | Z13.89 |
| LOINC Code | 81208-0 |
| DHA Facility License & Laboratory Address | License: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians