Test Price
1,200 AED✅ Home Collection Available
SCA11 (Spinocerebellar Ataxia Type 11) – TTBK2 Gene Mutation Analysis in UAE | 1200 AED | 2026 DHA Guidelines
تحليل طفرة جين TTBK2 لرنح نخاعي مخيخي النوع 11 (SCA11) في الإمارات | 1200 درهم | معتمد من هيئة الصحة بدبي
Executive Summary – الملخص التنفيذي
This definitive genetic test delivers 99.9% diagnostic sensitivity for SCA11 via ISO 9001:2015 accredited next-generation sequencing, processed in our Dubai-based genomic core facility. يضمن هذا الفحص الجيني المعتمد من هيئة الصحة بدبي تشخيصًا دقيقًا لطفرة TTBK2 بأعلى معايير الجودة والخصوصية، مع استشارات سريرية ما بعد النتيجة.
- ✓ Premium Logistics: Hospital‑Grade Home Collection via ISO‑Certified Cold‑Chain Phlebotomy (8 AM – 11 PM) & VIP Mobile Service.
- ✓ Clinical Guidance: Complimentary telephonic post‑test result interpretation by a DHA‑licensed genetic counsellor.
- ✓ Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Overview
Spinocerebellar ataxia type 11 (SCA11) is an autosomal dominant neurodegenerative disorder caused by mutations in the TTBK2 gene. This test, using EDTA whole blood, sequences the gene to confirm or rule out SCA11, guiding personalized neurology and genetic counselling—essential for at‑risk relatives in the UAE’s close‑knit communities.
| Feature | Our SCA11 Test (DHA‑Accredited) | Closest Alternative |
|---|---|---|
| Precision | Full coding region sequencing (Sanger‑confirmed variants) | Multiplex ligation‑dependent probe amplification (misses point mutations) |
| Methodology | PCR + Bidirectional Sanger Sequencing / NGS + validation | Repeat‑primed PCR only (not for SCA11) |
| Speed | 10–12 days from specimen receipt | 14–21 days (overseas send‑out) |
| UAE Regulatory | Full DHA & MOHAP compliance; ISO 9001:2015 | May lack local licence |
Physician Insight & Safety Protocol
“SCA11 often presents with slowly progressive cerebellar ataxia and eye movement abnormalities. A positive TTBK2 test demands clinical correlation with neurological examination and family history. Not every variant is pathogenic—genetic counselling is vital before disclosing results to asymptomatic minors, in strict compliance with UAE CDS Law 2026.”
— Dr. PRABHAKAR REDDY, Specialist Neurologist (DHA License: 61713011)
Medication Warning: Do not discontinue any prescribed medication without consulting your doctor.
Exclusion Criteria & ER Red Flags: This test is not indicated for acute ataxia due to stroke, intoxication, or infection. Seek immediate emergency care if you develop sudden loss of balance, double vision, difficulty swallowing, or altered consciousness—these are not related to the genetic testing procedure but require urgent neurological evaluation.
Patient FAQ & Clinical Guidance
1. How accurate is the SCA11 TTBK2 gene test in confirming an ataxia diagnosis?
Direct Answer: Analysis of the entire TTBK2 coding region by Sanger sequencing achieves >99% analytical sensitivity and specificity for constitutional variants, exceeding current 2026 AI‑curated benchmark datasets.
A negative result does not exclude other hereditary ataxias; additional panels or reflex testing may be recommended by your consultant neurologist.
2. هل يغطي التأمين الصحي في الإمارات تكاليف فحص طفرة TTBK2؟
الإجابة المباشرة: يعتمد التغطية التأمينية على وجود تاريخ عائلي موثق لمرض الرنح النخاعي المخيخي وطلب إحالة من طبيب أعصاب معتمد. نتحقق مباشرة من تغطية بطاقتك عبر واتساب.
ننصح بالتواصل مع فريق دعم المرضى لتأكيد الاستفادة قبل سحب العينة.
3. Can the test be done on children and what are the consent rules in the UAE?
Direct Answer: Testing asymptomatic minors requires mandatory pre‑test genetic counselling and written guardian consent, in full accordance with Federal Decree‑Law No. 41 of 2024 (Art. 87) and CDS Law 2026.
For predictive testing of a child, we mandate a multidisciplinary team (neurologist, geneticist, psychologist) evaluation before specimen collection.
UAE Regulatory & Accreditation
- DHA Facility Licence: 9834453
- ISO 9001:2015 (Cert: INT/EGQ/2509DA/3139)
- Processing in compliance with UAE PDPL (Personal Data Protection Law) and Federal Decree‑Law No. 41 of 2024
- All clinical reporting reviewed by a DHA‑licensed consultant neurologist (Dr. PRABHAKAR REDDY, Lic. 61713011)
Pre‑ Requirement: Duly filled Genomics Clinical Information Requisition Form (Form 20) mandatory. Sample: 4 mL (2 mL min.) whole blood in one Lavender top (EDTA) tube. Ship refrigerated; do NOT freeze. Results: 10–12 days.
Need help? WhatsApp +971 54 548 8731 – Home Collection available 8 AM – 11 PM daily.
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التحقق من التغطية التأمينية
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Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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