Test Price
2,800 AED✅ Home Collection Available
KCNC3 Gene Spinocerebellar Ataxia Type 13 (SCA13) Genetic Test in UAE | 2,800 AED
Executive Summary & Core Metrics
Diagnostic Precision Guaranteed – 99.9% analytical sensitivity and specificity via Next Generation Sequencing (NGS) in an ISO 15189‑aligned laboratory.
VIP Mobile Phlebotomy & Cold-Chain Home Collection – Available daily across all UAE emirates from 8 AM to 11 PM. Samples accepted: whole blood (EDTA), extracted DNA, or FTA card blood spots.
Post‑Test Clinical Guidance – Complimentary pre- and post-test genetic counseling session with our DHA‑licensed Consultant Medical Geneticist.
Insurance & Billing – Direct billing verification via WhatsApp: +971 54 548 8731.
Test Overview & Methodology
This single‑gene test sequences the entire coding region of KCNC3 using Next Generation Sequencing (NGS) to confirm or exclude a pathogenic variant responsible for autosomal dominant Spinocerebellar Ataxia Type 13 (SCA13). Comprehensive coverage of exons and flanking intronic regions ensures highly accurate variant detection.
| Parameter | This Test (NGS) | Alternative (Sanger) |
|---|---|---|
| Analytical Sensitivity | >99.9% (SNVs, small indels) | ~99% per exon (misses deep intronic variants) |
| Turnaround Time | 3 – 4 weeks | 4 – 6 weeks |
| Variant Detection | Full gene coverage (exons ±15 bp flanking introns) | Targeted Sanger of known exons only |
Physician Insight & Safety Protocols
“This KCNC3 genetic test provides definitive molecular confirmation for SCA13 and enables accurate familial risk stratification. However, genetic results must always be interpreted in the full context of the patient’s neurological examination, family pedigree, and symptom progression. A negative result does not exclude other hereditary or sporadic ataxias. Predictive testing for asymptomatic adult relatives should be accompanied by comprehensive genetic counseling to ensure informed decision-making.”
– Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Clinical Advisory & Pre-test Requisites
- Informed Consent: A signed genetic testing consent form is mandatory prior to sample collection, outlining the scope of testing, implications for family members, and data handling policies.
- Medication Review: Please inform the geneticist about any ongoing treatments. Do not alter prescribed therapies solely based on genetic findings without consulting your specialist.
Exclusion Criteria & Sample Integrity
- Acute Neurological Emergency: New onset of severe dysphagia, respiratory distress, or altered consciousness requires immediate emergency medical care (call 998 in UAE). This test is a stable elective diagnostic procedure, not an acute diagnostic panel.
- Hematopoietic Stem Cell Transplant (HSCT) Recipients: Genetic testing on peripheral blood may reflect donor DNA rather than the patient’s germline. Please advise the laboratory if the patient has a history of HSCT. An alternative specimen like a buccal swab may be required.
- Recent Blood Transfusion: Patients who have received a blood transfusion within the past 8 weeks should postpone collection to avoid chimerism confounders, or provide a pre-transfusion specimen.
Patient FAQ & Clinical Guidance
1. What does a positive KCNC3 variant mean for my health and family?
A confirmed pathogenic variant in KCNC3 establishes a molecular diagnosis of Spinocerebellar Ataxia Type 13 (SCA13). This is an autosomal dominant condition, meaning each biological child has a 50% risk of inheriting the variant. Clinical progression typically involves progressive gait and limb incoordination over decades. Penetrance and expressivity can vary, making genetic counseling essential for all at-risk family members.
2. How is the sample collected and is home service available in Dubai and Abu Dhabi?
We offer VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection across all emirates, daily from 8 AM to 11 PM. Acceptable specimens include whole blood (EDTA tube), extracted DNA, or a single drop of blood on an FTA card. The sample is processed in a DHA-licensed, ISO 15189 aligned facility (DNA Labs UAE).
3. Is genetic counseling mandatory before and after this test in the UAE?
Yes. In alignment with UAE health regulations governing predictive genetic testing (Federal Law No. 2 of 2019), pre- and post-test genetic counseling with a qualified professional is mandatory. This ensures fully informed consent, addresses psychological implications, and facilitates tailored risk communication for the patient and their family.
UAE Regulatory & Data Privacy Adherence
Regulatory & Data Privacy Governance
DNA Labs UAE strictly adheres to Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Your genetic data is encrypted, access‑controlled, and processed solely for the purpose of diagnostic reporting. It is never shared with third parties without explicit written consent. Clinical safety and patient consent protocols are conducted in accordance with Federal Decree-Law No. 4 of 2016 on Medical Liability.
As a DHA‑licensed facility (License No: 1143), we uphold the highest standards of confidentiality and laboratory practice.
Clinical & Logistical Metadata
| Test Name | KCNC3 Gene Spinocerebellar Ataxia Type 13 (SCA13) Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 weeks |
| Sample Type / Matrix | Whole Blood (EDTA), Extracted DNA, or FTA Card Blood Spot |
| Methodology Used | Next Generation Sequencing (NGS) – Full Gene Coverage |
| ICD-10-CM Code | G11.8 |
| LOINC Code | 55233-1 |
| DHA Facility License & Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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