Test Price
2,800 AED✅ Home Collection Available
ANO10 Gene Spinocerebellar Ataxia Type 10, Autosomal Recessive Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل جين ANO10 ومرض الرنح النخاعي المخيخي النوع 10، المتنحي جسديًا، بتقنية التسلسل الجيني NGS في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
UAE Clinical Executive Summary
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing.
- Premium Logistics: Paid Hospital-Grade Home Collection via ISO Certified Cold-Chain Home Collection & VIP Mobile Phlebotomy (8 AM - 11 PM).
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation delivered by DHA-licensed genetic counsellors.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
ملخص تنفيذي: يقدم هذا التحليل الجيني المتطور القائم على تقنية التسلسل من الجيل التالي (NGS) تشخيصًا دقيقًا لطفرة جين ANO10 المرتبطة بالرنح النخاعي المخيخي النوع 10 المتنحي جسديًا، وفقًا لإرشادات هيئة الصحة بدبي لعام 2026، مع استشارة وراثية شاملة ودعم لوجستي منزلي معتمد.
Overview
This next-generation sequencing (NGS) test comprehensively analyses the entire ANO10 gene to detect pathogenic variants responsible for autosomal recessive spinocerebellar ataxia type 10 (SCAR10), enabling definitive diagnosis and informed family planning.
يقوم هذا الاختبار القائم على التسلسل الجيني الشامل بتحليل كامل جين ANO10 للكشف عن الطفرات المسببة للمرض، مما يتيح تشخيصًا نهائيًا ويساعد في التخطيط العائلي الدقيق.
| Feature | Our NGS Test (ANO10 Gene) | Conventional Sanger Sequencing |
|---|---|---|
| Precision | >99.9% sensitivity for all coding regions & splice sites | ~98% sensitivity, limited to targeted exons only |
| Methodology | Next Generation Sequencing (NGS) with high-depth coverage | Sanger sequencing (single amplicon per exon) |
| Turnaround Time | 3 to 4 Weeks | 6 to 8 Weeks |
Physician Insight & Safety Protocol
“This genetic test identifies pathogenic ANO10 variants with high confidence, but clinical correlation with neurological examination and family history is essential. A positive result should be interpreted alongside a comprehensive clinical evaluation, and patients should be counselled regarding the autosomal recessive inheritance pattern. I emphasize that genetic testing does not replace clinical judgment; any decision to alter current therapy must be made by the managing neurologist.”
— Dr. Prabhakar Reddy, DHA License: 61713011
Medication Warning:
Do not discontinue any prescribed medication or adjust neurological therapy without consulting your treating physician. Test results are for diagnostic clarification, not immediate treatment change.
Patient Safety – Exclusion Criteria & Emergency Red Flags
Exclusion Criteria (Home Collection): active febrile illness, recent surgery or blood transfusion within 72 hours, known haemoglobin <8 g/dL, or inability to provide informed consent/valid identification.
Emergency Red Flags (Seek Immediate Medical Attention): sudden worsening of ataxia, loss of consciousness, respiratory difficulty, or new-onset seizures. These symptoms require urgent neurological evaluation, not routine genetic testing.
Patient FAQ & Clinical Guidance
Q: How accurate is the ANO10 NGS test in detecting the genetic cause of spinocerebellar ataxia type 10?
The test achieves >99.9% analytical sensitivity and specificity for single nucleotide variants and small indels in the ANO10 gene when using a high-depth NGS platform. Validation data confirm it outperforms conventional methods in detecting deep intronic or mosaic variants, providing a comprehensive mutational analysis.
س: كم تستغرق نتيجة تحليل جين ANO10 وما الخطوات بعد ظهورها؟
تستغرق نتيجة التحليل من 3 إلى 4 أسابيع، ويتبع ذلك جلسة استشارة وراثية هاتفية معتمدة من هيئة الصحة بدبي لتفسير النتيجة. في حال كانت النتيجة إيجابية، يُنصح بفحص باقي أفراد العائلة وفقًا لنمط الوراثة المتنحي الجسدي.
Q: Is a home visit available for sample collection, and how is the sample transported?
Yes, a DHA-compliant premium home collection service is available daily from 8 AM to 11 PM, with ISO-certified cold-chain transport. The phlebotomist draws 2-5 mL of whole blood into a DNA-stabilizing tube, which is immediately placed in a validated cold chain to preserve nucleic acid integrity until processing.
Pre- Information & Logistics
- Clinical history of the patient, including age at onset, neurological symptoms, and family pedigree chart, must be provided.
- A genetic counselling session to draw a detailed pedigree of family members affected by ataxia is mandatory prior to testing.
- Acceptable sample types: Whole Blood, Extracted DNA, or One Drop of Blood on an FTA Card.
- Turnaround Time: 3 to 4 Weeks from receipt of sample in the laboratory.
- Price: 2800 AED inclusive of DHA-mandated genetic counselling support.
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
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Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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