Test Price
2,800 AED✅ Home Collection Available
SMN1 Gene Sequencing (SMA Type 3) – Genetic Test in Dubai Healthcare City | 2800 AED
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Certified Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (daily 8 AM – 11 PM).
- Clinical Guidance: Telephonic Post-Test Genetic Counselling with a DHA-licensed Consultant Medical Geneticist.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The SMN1 Gene Sequencing test utilizes high-coverage Next-Generation Sequencing (NGS) with integrated dosage analysis to detect copy number variations (exon 7/8 deletions or duplications) and point mutations. This confirms a clinical diagnosis of Spinal Muscular Atrophy Type 3 (Kugelberg‑Welander disease) and guides carrier screening and family planning. The test also evaluates SMN2 modifier copy number, improving prognostic accuracy.
| Feature | Our SMN1 NGS Test | Closest Alternative (Standard MLPA Only) |
|---|---|---|
| Precision & Scope | Simultaneous detection of exon 7/8 copy number, point mutations, and SMN2 modifier copy number | Only exon 7/8 deletion/duplication – misses 5–10% of cases with intragenic mutations |
| Methodology | High‑coverage NGS with dosage analysis (ISO 9001:2015 certified pipeline) | MLPA with limited point‑mutation analysis |
| Turnaround Time | 3 to 4 Weeks | 4 to 6 Weeks |
| Regulatory & Accreditation | ISO 9001:2015, UAE PDPL, Federal Law No. 2 of 2019 on ICT in Health | Often limited to basic CAP accreditation |
| Price | 2800 AED | 2500–3200 AED (variable, less comprehensive) |
Physician Insight & Safety Protocols
“As a Consultant Medical Geneticist, I emphasise that this test provides definitive molecular confirmation for SMA type 3 when correlated with clinical and electromyographic findings. A negative result does not exclude other motor neuron disorders; all findings must be integrated by a specialist before initiating therapy. Tele‑genetic counselling is available for result interpretation.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Important Clinical Advisory
Medication Warning: Do not discontinue prescribed medication without consulting your doctor. This test does not replace ongoing neurological care.
Emergency Red Flags: If during the testing process you experience sudden muscle weakness, respiratory difficulty, or swallowing problems, seek immediate medical attention at the nearest emergency department. These signs may indicate unrelated acute neuromuscular compromise.
Exclusion Criteria
This test is not indicated for asymptomatic individuals without a family history of SMA unless as part of a formal genetic counselling programme. It is not designed for forensic, paternity, or prenatal diagnosis without prior specialist referral.
Patient FAQ & Clinical Guidance
1. What is the diagnostic accuracy of the SMN1 NGS test for SMA type 3?
The test achieves 99.9% diagnostic sensitivity by simultaneously detecting exon 7/8 deletions, point mutations, and SMN2 copy number modifiers using high-coverage NGS. This comprehensive approach minimises false negatives and clarifies prognosis by assessing the SMN2 gene dosage, which influences disease severity. All results are reviewed by a DHA‑licensed clinical geneticist before release.
2. How long does it take to receive my results, and what does the home collection involve?
You will receive your comprehensive report within 3 to 4 weeks after a premium home blood draw performed by a certified phlebotomist between 8 AM and 11 PM, using ISO‑certified cold‑chain transport. A pre‑test genetic counselling session ensures proper family pedigree documentation; a single tube of whole blood or extracted DNA is accepted.
3. Is this test covered by insurance and are there legal requirements in the UAE?
We offer direct insurance billing verification via WhatsApp. This genetic test strictly adheres to the UAE Personal Data Protection Law (PDPL) and Federal Law No. 2 of 2019 concerning the use of ICT in health fields. Explicit consent is required for genetic data processing, including a tele‑counselling session. The laboratory holds ISO 9001:2015 accreditation and DHA facility license 1143.
UAE Regulatory & Data Privacy Adherence
DNA Labs UAE operates under strict compliance with UAE Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and patient consent are governed by Federal Decree-Law No. 4 of 2016 on Medical Liability. All genetic data is processed with explicit consent and stored securely. The facility is fully licensed by the Dubai Health Authority (DHA License No. 1143).
Clinical & Logistical Metadata
| Test Name | SMN1 Gene Sequencing (SMA Type 3) – NGS with Dosage Analysis |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type / Matrix | Whole Blood (Peripheral) or Extracted DNA – VIP Mobile Phlebotomy Home Collection Available |
| Methodology Used | Next-Generation Sequencing (NGS) with integrated dosage analysis (exon 7/8 CNV and point mutations) |
| ICD-10-CM Code | G12.1 |
| LOINC Code | 81378-8 |
| DHA Facility License & Laboratory Address Invariants | DHA License No: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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