Test Price
2,800 AED✅ Home Collection Available
WNT10B Gene Split-Hand/Foot Malformation Type 6 Genetic Test in UAE | 2800 AED
Executive Summary & Core Metrics
Executive Summary
- Diagnostic Accuracy: 99.9% analytical sensitivity via ISO‑accredited NGS processing.
- Premium Logistics: ISO‑certified cold‑chain home collection with VIP mobile phlebotomy (daily 8 AM – 11 PM).
- Clinical Guidance: Post‑test telephonic consultation for result interpretation and genetic counseling referral.
- Insurance & Billing: Direct pre‑authorization verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The WNT10B gene NGS test detects pathogenic variants associated with split‑hand/foot malformation type 6 (SHFM6), a rare congenital limb anomaly. This advanced sequencing technology provides a definitive molecular diagnosis, guiding pediatric management, family genetic counseling, and recurrence risk assessment.
| Feature | Our Test (NGS – WNT10B Full Gene) | Closest Alternative (Single‑Site Sanger) |
|---|---|---|
| Precision | 99.9% sensitivity, detects SNVs, indels, CNVs across all coding regions | Lower sensitivity for CNVs; limited to targeted hotspot mutations |
| Methodology | Next‑Generation Sequencing (Illumina® platform) with bioinformatics validation | Sanger sequencing (targeted analysis only) |
| Turnaround Time | 3 to 4 weeks | 2 to 3 weeks |
Physician Insight & Safety Protocols
"As a consultant in medical genetics, I recognize the profound impact a diagnosis of split‑hand/foot malformation type 6 can have on a family and the individual. This NGS‑based test offers definitive molecular confirmation, enabling accurate recurrence risk counseling and informed family planning decisions. However, results must always be correlated with the complete clinical presentation and pedigree analysis."
– Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration No. 9294403
Genetic Counseling Advisory
⚠️ Important Advisory
This test provides diagnostic information only. All results require confirmation and interpretation by a qualified medical geneticist. Genetic counseling is strongly recommended before and after testing for all individuals, including asymptomatic family members, to fully understand implications, inheritance patterns, and available management options.
Exclusion Criteria & Emergency Red Flags
Contraindications & Safety Alerts
- Recent whole‑blood transfusion (within 2 weeks) – may interfere with germline DNA analysis.
- Known active localized infection at phlebotomy site.
- Allogeneic bone marrow transplant within the past 30 days.
- Patients unable to provide legal consent; for minors, parental/guardian consent is mandatory under Federal Decree-Law No. 4 of 2016 on Medical Liability.
🚨 If your child shows respiratory distress, cyanosis, or severe limb anomalies affecting the airway or feeding, seek emergency pediatric surgical consultation before proceeding with this genetic test.
Patient FAQ & Clinical Guidance
1. What is the WNT10B genetic test used for?
WNT10B gene testing identifies pathogenic variants responsible for split‑hand/foot malformation type 6 (SHFM6). It provides a precise molecular diagnosis, enabling tailored clinical management, accurate recurrence risk estimation, and informed family planning for affected individuals and their relatives.
2. How is the test performed and how long do results take?
A peripheral whole‑blood sample or DNA FTA card is collected and processed using next‑generation sequencing on the Illumina® platform. Results are typically reported within 3 to 4 weeks from sample receipt.
3. Is home sample collection available in Dubai and Abu Dhabi?
Yes, ISO‑certified temperature‑controlled cold‑chain home collection is available daily from 8 AM to 11 PM across the UAE, including Dubai and Abu Dhabi, by our VIP mobile phlebotomy team.
UAE Regulatory & Data Privacy Adherence
UAE Compliance: This service adheres strictly to Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL), Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields, and Federal Decree-Law No. 4 of 2016 on Medical Liability. The laboratory holds DHA facility license No. 1143, ISO 9001:2015 certification (Cert: INT/EGQ/2509DA/3139), and follows mandatory genetic counseling protocols before sample collection.
Clinical & Logistical Metadata
| Test Name | WNT10B Gene Split-Hand/Foot Malformation Type 6 Genetic Test (NGS) |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3 to 4 weeks |
| Sample Type / Matrix | Whole Blood or DNA FTA Card |
| Methodology Used | Next‑Generation Sequencing (Illumina® platform) |
| ICD-10-CM Code | Q71.6 (Split-hand/split-foot malformation) |
| LOINC Code | 51966-0 (WNT10B gene mutation analysis) |
| DHA Facility License & Laboratory Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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