Test Price
2,800 AED✅ Home Collection Available
RNF216 Gene (Gordon Holmes Syndrome) Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل جين RNF216 (متلازمة جوردون هولمز) في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Executive Summary – 2800 AED All‑Inclusive
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO‑Accredited Processing.
- Premium Logistics: Hospital‑Grade Home Collection (8 AM–11 PM) with cold‑chain transport.
- Clinical Guidance: Telephonic post‑test result interpretation by a DHA‑licensed clinician.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
يضمن هذا التحليل دقة تشخيصية بنسبة 99.9% عبر مختبر معتمد من ISO، مع خدمة سحب منزلي معتمدة.
Complying with UAE Federal Decree‑Law No. 41 of 2024, Art. 87; CDS Law 2026 (Minors); UAE PDPL. ISO 9001:2015 Cert: INT/EGQ/2509DA/3139.
Overview – Single‑Gene NGS Test for Gordon Holmes Syndrome
This Genetic Test analyses the entire coding region and exon‑intron boundaries of the RNF216 gene to confirm Gordon Holmes syndrome, a rare autosomal recessive neurodegenerative disorder. (يكتشف تحليل تسلسل الجين الكامل طفرات جين RNF216 المسؤولة عن متلازمة جوردون هولمز.)
| Feature | Our Test (NGS) | Closest Alternative (Sanger Sequencing) |
|---|---|---|
| Methodology | Next‑Generation Sequencing (NGS) | Sanger sequencing |
| Genomic Coverage | Complete coding region + splice sites | Targeted known mutation only |
| Turnaround Time | 3–4 Weeks | 2–3 Weeks |
| Diagnostic Yield | >99% against reference | ~95% for single variant |
| Price (AED) | 2800 | ~2400 |
ICD‑10‑CM (2026): G31.8 (Other degenerative diseases of nervous system), E23.3 (Hypothalamic dysfunction), Z13.79 (Encounter for genetic screening) | LOINC: 101649‑4
Physician Insight & Safety Protocol
Dr. PRABHAKAR REDDY – DHA License No. 61713011
“A positive RNF216 result must be correlated with clinical manifestations of progressive cerebellar ataxia, hypogonadotropic hypogonadism, and cognitive decline. Genetic counselling is essential before and after testing, as early identification can guide family planning and symptomatic management.”
Safety & Exclusion Criteria
- ER Red Flags (seek immediate care): Acute neurological deterioration, severe unexplained headache with vision loss, new‑onset seizures, or loss of consciousness.
- Exclusion Criteria: Inability to provide informed consent; severe uncorrected coagulopathy (for blood draw); febrile illness on day of collection.
- Medication Warning: Do not discontinue prescribed medication without consulting your doctor. This test does not replace neurologic follow‑up.
- Minors require explicit consent from a legal guardian in compliance with UAE CDS Law 2026.
Patient FAQ & Clinical Guidance
1. What is the purpose of this RNF216 gene test?
This test identifies pathogenic variants in the RNF216 gene to confirm Gordon Holmes syndrome diagnosis in patients with progressive neurological decline and hypogonadism. It aids in distinguishing the condition from other ataxia syndromes and provides crucial information for family risk assessment and reproductive options.
يحدد هذا التحليل الطفرات الممرضة في جين RNF216 لتأكيد تشخيص متلازمة جوردون هولمز لدى المرضى الذين يعانون من تدهور عصبي مترقٍ وقصور الغدد التناسلية.
2. Which sample types are accepted and how is the collection done?
We accept whole blood, extracted DNA, or a dried blood spot on FTA card, allowing flexible home collection with cold‑chain transport. A certified phlebotomist arrives at your doorstep (8 AM–11 PM) and follows strict ISO‑certified protocols; the sample is immediately stabilized and shipped to our central lab.
نقبل الدم الكامل أو الحمض النووي المستخلص أو بقعة دم جافة على بطاقة FTA، مما يتيح سحبًا منزليًا مرنًا مع نقل مبرد.
3. How long does it take to receive results and what support is provided?
Results are typically reported within 3 to 4 weeks, with genetic counselling available upon request through our telephonic post‑ guidance. A board‑certified genetic counsellor will explain the findings, interpret variant significance, and discuss implications for family members.
تتوفر النتائج خلال 3 إلى 4 أسابيع مع استشارات وراثية عند الطلب عبر التوجيه الهاتفي بعد الفحص.
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توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
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All reports reviewed by DHA-Certified physicians