Test Price
2,800 AED✅ Home Collection Available
POMP Gene Keratosis Linearis with Ichthyosis Congenita and Sclerosing Keratoderma Genetic Test in UAE 2,800 AED – Verified Pricing
Executive Summary & Core Metrics
This NGS-based genetic test achieves 99.9% diagnostic sensitivity for pathogenic variants in the POMP gene associated with KLICK syndrome. The service is performed in an ISO 9001:2015 accredited laboratory with temperature-controlled cold-chain logistics for home sample collection. Post-test telephonic clinical guidance is provided by a Consultant Medical Geneticist. Insurance pre‑authorization and billing verification are available via WhatsApp.
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (daily 8 AM – 11 PM).
- Clinical Guidance: Telephonic Post-Test Clinical Guidance for result interpretation by our genetics specialist.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
This advanced next‑generation sequencing (NGS) test detects pathogenic variants in the POMP gene responsible for Keratosis linearis with ichthyosis congenita and sclerosing keratoderma (KLICK syndrome). The methodology covers 100% of the coding region plus intron‑exon boundaries, enabling detection of single nucleotide variants (SNVs), small insertions/deletions, and copy number variations (CNVs).
| Feature | Our POMP NGS Test | Closest Alternative (Sanger Sequencing) |
|---|---|---|
| Precision & Sensitivity | 99.9% diagnostic sensitivity for full gene variants | ~95% limited to known regions |
| Methodology | NGS – 100% coding region + intron boundaries | Capillary sequencing – exon‑by‑exon, slower |
| Turnaround Time | 3–4 weeks | 6–8 weeks |
| Variant Types Detected | SNVs, indels, CNVs | SNVs, small indels only |
Physician Insight & Safety Protocols
“For rare genodermatoses like KLICK syndrome, a molecular diagnosis through comprehensive POMP gene analysis is essential. It clarifies prognosis, guides surveillance, and enables family counseling. However, results must always be integrated with clinical findings from a dermatologist and a clinical geneticist.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Pre-Test Advisory & Consent
Clinical Notice
Prior to sample collection, a detailed family history and a three‑generation pedigree chart are required. A physician’s referral and written informed consent are mandatory. For minors under 18, consent must be provided by a legal guardian in accordance with UAE Federal Decree‑Law No. 4 of 2016 on Medical Liability. Please continue all prescribed medications; do not alter your regimen without consulting your doctor.
Exclusion Criteria & Emergency Red Flags
Exclusion Criteria & Emergency Red Flags
- Exclusion: Presence of active skin infection at the intended venipuncture site.
- Exclusion: Inability to provide informed consent or a known contraindication to venipuncture (severe bleeding disorder, lack of suitable veins).
- Red Flags: If you experience severe dizziness, excessive bleeding, or signs of infection (redness, swelling, fever) after collection, seek immediate medical attention.
- Red Flags: Sudden worsening of skin lesions accompanied by fever requires urgent dermatology evaluation.
Patient FAQ & Clinical Guidance
1. What is the POMP gene test for?
This NGS test analyzes the entire POMP gene to confirm or exclude a genetic cause of KLICK syndrome. It detects point mutations, deletions, duplications, and helps distinguish this condition from other ichthyoses and palmoplantar keratodermas.
2. How accurate is this test?
Diagnostic sensitivity exceeds 99.9% for germline variants, validated under ISO 9001:2015 protocols. Accuracy is ensured through bidirectional sequencing and rigorous bioinformatics pipelines adhering to ACMG guidelines.
3. What is the turnaround time and sample requirement?
Results are available within 3 to 4 weeks from a simple blood draw (peripheral whole blood) or a dried blood spot on an FTA card. No fasting is necessary. Our VIP mobile phlebotomy team can collect the sample at your home with temperature-controlled cold-chain transport.
UAE Regulatory & Data Privacy Adherence
Legal and Data Protection Framework
All genetic data is processed in strict compliance with UAE Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and patient consent are governed by Federal Decree-Law No. 4 of 2016 on Medical Liability. The laboratory holds a valid DHA facility license and operates under ISO 9001:2015 certification.
Clinical & Logistical Metadata
| Test Name | POMP Gene Keratosis Linearis with Ichthyosis Congenita and Sclerosing Keratoderma Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3-4 Weeks |
| Sample Type / Matrix | Peripheral Whole Blood or Dried Blood Spot (FTA Card) |
| Methodology Used | Next-Generation Sequencing (NGS) – Full Gene Sequencing |
| ICD-10-CM Code | Q80.8 (Other congenital ichthyosis) |
| LOINC Code | 21647-1 (Gene rearrangement analysis, Blood or Tissue) |
| DHA Facility License & Laboratory Address | DHA License: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | Corporate Lab: DNA Labs UAE |
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ISMS 27001:2022
ISO Accredited
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