Test Price
2,800 AED✅ Home Collection Available
LONP1 Gene Sequencing for CODAS Syndrome (Genetic Test in UAE | 2800 AED | DHA Licensed Laboratory)
Executive Summary & Core Metrics
- ✓ Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015‑accredited next‑generation sequencing and bioinformatics pipeline.
- ✓ Premium Logistics: VIP Mobile Phlebotomy & Temperature‑Controlled Cold‑Chain Home Collection (Available daily from 8 AM to 11 PM).
- ✓ Clinical Guidance: Complimentary post‑test telephonic result interpretation by a DHA‑licensed genetic counsellor.
- ✓ Insurance: Direct billing verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
This advanced next‑generation sequencing (NGS) test screens the entire coding region of the LONP1 gene, diagnosing autosomal recessive CODAS syndrome (Cerebral, Ocular, Dental, Auricular, Skeletal anomalies). The test is performed on peripheral whole blood using an ISO‑certified NGS platform with ≥ 99.9% analytical sensitivity for single‑nucleotide variants and small insertions/deletions.
| Feature | Our Test (NGS) | Closest Alternative |
|---|---|---|
| Technology | Full Gene Sequencing (NGS) | Single‑variant PCR / panel |
| Coverage | All coding exons ±10 bp splice sites | Limited to known hotspot mutations |
| Turnaround Time | 3 – 4 Weeks | 4 – 6 Weeks |
| Clinical Validity | ≥ 99.9% sensitivity for pathogenic SNVs/indels | May miss novel mutations |
Physician Insight & Safety Protocols
“CODAS syndrome embodies a unique constellation of multi‑system anomalies, and LONP1 molecular confirmation is essential for accurate prognosis and familial recurrence risk estimation. I urge every patient to pair this test with formal genetic counselling and clinical correlation, as genotype‑phenotype variability exists.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics | DHA Registration ID: 9294403
Advisory: Medication & Treatment Continuation
Do not discontinue prescribed medication or alter treatment without consulting your physician.
Exclusion Criteria & Emergency Red Flags
- Unable to provide informed consent (mandatory genetic counselling session required).
- Severe coagulopathy or active bleeding that contraindicates venipuncture.
- Acute febrile illness – postpone collection until 48 hours symptom‑free.
- ER Warning: If a pathogenic variant is reported and the patient develops new‑onset seizures, encephalopathy, or acute visual/hearing loss, seek immediate paediatric neurology/ophthalmology evaluation.
Patient FAQ & Clinical Guidance
1. What exactly does the LONP1 NGS test detect?
Snippet: This test sequences all coding exons of the LONP1 gene to identify pathogenic single‑nucleotide variants and small insertions/deletions responsible for CODAS syndrome, with ≥ 99.9% analytical sensitivity.
2. Who should consider this test?
Snippet: Ideal candidates include paediatric patients with clinical features of CODAS syndrome, unaffected siblings of a proband, couples planning pregnancy with a family history, and individuals seeking carrier status clarification.
3. What sample is required and how is it collected?
Snippet: A whole blood sample in an EDTA tube (or an FTA card dried blood spot) is collected by our DHA‑licensed phlebotomists during the home visit; no fasting or special preparation is needed. Mobile phlebotomy is available daily from 8 AM to 11 PM.
UAE Regulatory & Data Privacy Adherence
Regulatory Compliance & Data Privacy
This test is performed in strict accordance with:
- Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) – all patient data processed within the UAE.
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields – ensuring secure handling of electronic health records.
- Federal Decree‑Law No. 4 of 2016 on Medical Liability – governing clinical testing safety and patient consent.
- ISO 9001:2015 Certified (Cert: INT/EGQ/2509DA/3139) – guaranteeing quality‑managed laboratory processes.
Clinical & Logistical Metadata
| Test Name | LONP1 Gene Sequencing (CODAS Syndrome) |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3 – 4 Weeks |
| Sample Type / Matrix | Whole blood (EDTA) or FTA card dried blood spot |
| Methodology Used | Next‑Generation Sequencing (NGS) – full coding exons ±10 bp splice sites |
| ICD-10-CM Code | Q87.8, Z13.71 |
| LOINC Code | 21636-6 |
| DHA Facility License & Lab Address | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | License: 1143 | DNA Labs UAE |
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Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians