Test Price
2,800 AED✅ Home Collection Available
LONP1 Gene Sequencing for CODAS Syndrome (Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل جين LONP1 لمتلازمة CODAS في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
📌 Executive Summary – Trust Indicators
- ✓ Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015‑accredited next‑generation sequencing and bioinformatics pipeline.
- ✓ Premium Logistics: Paid Hospital‑Grade Home Collection using ISO‑certified cold‑chain transport & VIP Mobile Phlebotomy (8 AM–11 PM).
- ✓ Clinical Guidance: Complimentary post‑test telephonic result interpretation by a DHA‑licensed genetic counsellor.
- ✓ Insurance: Direct billing verification via WhatsApp +971 54 548 8731.
ضمان الدقة بنسبة 99.9% مع التجميع المنزلي المعتمد، والتوجيه السريري الهاتفي، والتحقق من التأمين عبر الواتساب.
Test Overview
This advanced next‑generation sequencing (NGS) test screens the entire coding region of the LONP1 gene, diagnosing autosomal recessive CODAS syndrome (Cerebral, Ocular, Dental, Auricular, Skeletal anomalies). يكشف التحليل الجيني عن الطفرات المسببة لمتلازمة CODAS النادرة، ويخدم التشخيص السابق للولادة وحاملي المرض.
| Feature | Our Test (NGS) | Closest Alternative |
|---|---|---|
| Technology | Full Gene Sequencing (NGS) | Single‑variant PCR / panel |
| Coverage | All coding exons ±10 bp splice sites | Limited to known hotspot mutations |
| Turnaround Time | 3 – 4 Weeks | 4 – 6 Weeks |
| Clinical Validity | ≥ 99.9% sensitivity for pathogenic SNVs/indels | May miss novel mutations |
Physician Insight & Safety Protocol
“CODAS syndrome embodies a unique constellation of multi‑system anomalies, and LONP1 molecular confirmation is essential for accurate prognosis and familial recurrence risk estimation. I urge every patient to pair this test with formal genetic counselling and clinical correlation, as genotype‑phenotype variability exists.”
— Dr. PRABHAKAR REDDY, DHA License 61713011
⛔ Do not discontinue prescribed medication or alter treatment without consulting your physician.
Exclusion Criteria & Emergency Red Flags
- Unable to provide informed consent (mandatory genetic counselling session required).
- Severe coagulopathy or active bleeding that contraindicates venipuncture.
- Acute febrile illness – postpone collection until 48 hours symptom‑free.
- ER Warning: If a pathogenic variant is reported and the patient develops new‑onset seizures, encephalopathy, or acute visual/hearing loss, seek immediate paediatric neurology/ophthalmology evaluation.
UAE Regulatory Compliance & Data Privacy
This test is performed in strict accordance with:
- Federal Decree‑Law No. 41 of 2024 on Genetic Data & Biobanks (Article 87 – genetic test consent & confidentiality).
- CDS Law 2026 – explicit parental/guardian consent required for minors.
- UAE PDPL (Federal Decree‑Law No. 45 of 2021) – all patient data processed within the UAE.
- ISO 9001:2015 Certified (Cert: INT/EGQ/2509DA/3139) – guaranteeing quality‑managed laboratory processes.
Patient FAQ & Clinical Guidance
1. What exactly does the LONP1 NGS test detect?
Snippet: This test sequences all coding exons of the LONP1 gene to identify pathogenic single‑nucleotide variants and small insertions/deletions responsible for CODAS syndrome, with ≥ 99.9% analytical sensitivity.
يكشف التحليل الطفرات المسببة لمتلازمة CODAS بفحص جميع الإكسونات المشفرة لجين LONP1 بدقة تتجاوز 99.9%.
2. Who should consider this?
Snippet: Ideal candidates include paediatric patients with clinical features of CODAS syndrome, unaffected siblings of a proband, couples planning pregnancy with a family history, and individuals seeking carrier status clarification.
ينصح به للأطفال المصابين بأعراض متلازمة CODAS وللأقارب حاملي الطفرة وللأزواج الذين يخططون للحمل مع تاريخ عائلي.
3. What sample is required and how is it collected?
Snippet: A whole blood sample in an EDTA tube (or an FTA card dried blood spot) is collected by our DHA-licensed phlebotomists during the home visit; no fasting or special preparation is needed.
يتم جمع عينة دم كاملة أو نقطة دم على بطاقة FTA خلال الزيارة المنزلية، دون الحاجة لتحضيرات خاصة.
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians