Test Price
2,800 AED✅ Home Collection Available
LMX1B Gene Nail‑Patella Syndrome (NPS) DNA Test | 2,800 AED
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO‑accredited processing using NGS full‑gene sequencing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
- Clinical Guidance: Telephonic post‑test clinical interpretation and genetic counselling included with your report.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The LMX1B Gene Nail‑Patella Syndrome (NPS) DNA Test is a high‑precision genetic analysis utilizing Next Generation Sequencing (NGS) to detect pathogenic variants in the LMX1B gene. This test provides a definitive molecular diagnosis for Nail‑Patella syndrome, an autosomal dominant disorder characterized by developmental abnormalities of the nails, knees, elbows, and kidneys. Full exon and intronic boundary coverage ensures the capture of both known and novel disease-causing variants.
| Feature | Our Test (NGS Full‑Gene Sequencing) | Closest Alternative (Sanger Single‑Variant) |
|---|---|---|
| Precision | 99.9% diagnostic sensitivity – detects novel & known variants | ~95% for targeted mutations; novel variants often missed |
| Methodology | Next Generation Sequencing (NGS) with full exon and intronic boundary coverage | Chain‑termination (Sanger) sequencing, single‑variant analysis |
| Turnaround | 3‑4 Weeks | 4‑6 Weeks |
Physician Insight & Safety Protocols
“As a Consultant Medical Genetics, I recognize the profound impact a definitive genetic diagnosis can have on managing hereditary skeletal and renal disorders. This NGS-based assay provides comprehensive coverage of the LMX1B gene, enabling the detection of both known and novel variants. It is crucial, however, that results are interpreted within the full clinical context by a qualified geneticist.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Safety & Advisory Precautions
Medication & Clinical Advisory
Do not discontinue prescribed medication without consulting your doctor.
Exclusion Criteria & Emergency Red Flags
- Patients currently on high‑dose immunosuppressants that may interfere with DNA extraction – consult the laboratory before sample collection.
- If you experience sudden vision changes, severe abdominal pain, or rapid kidney function decline, seek immediate medical attention – a gene test is not a substitute for emergency care.
Patient FAQ & Clinical Guidance
1. What is the LMX1B gene test used for?
This DNA test identifies mutations in the LMX1B gene to confirm a diagnosis of Nail‑Patella syndrome, an inherited disorder causing nail, skeletal, and kidney abnormalities in both adults and children. It helps differentiate NPS from other hereditary skeletal dysplasias.
2. How is the sample collected?
A certified phlebotomist conducts a VIP home visit to collect a simple whole blood sample or a single drop of blood on an FTA card. The specimen is transported using a temperature-controlled cold chain to ensure DNA stability.
3. What is the turnaround time and post-test support?
Results are delivered within 3‑4 weeks. Your comprehensive report includes a telephonic post-test genetic counselling session with a Consultant Medical Genetics to interpret the findings and guide clinical management.
UAE Regulatory & Data Privacy Adherence
Regulatory Compliance & Data Protection
DNA Labs UAE strictly adheres to the UAE’s robust legal framework for healthcare and data privacy. All genetic testing and patient data handling are conducted in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and patient consent protocols strictly follow Federal Decree-Law No. 4 of 2016 on Medical Liability. Our facility operates under DHA Facility License No. 1143.
Clinical & Logistical Metadata
| Test Name | LMX1B Gene Nail‑Patella Syndrome (NPS) DNA Test |
| Price (AED) | 2,800 |
| Turnaround Time | 3‑4 Weeks |
| Sample Type / Matrix | Whole Blood, FTA Card, or Buccal Swab |
| Methodology Used | Next Generation Sequencing (NGS) – Full Exon & Intronic Boundaries |
| ICD-10-CM Code | Q87.2 |
| LOINC Code | 82377-1 |
| DHA Facility License & Address | DHA License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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