Test Price
2,800 AED✅ Home Collection Available
LHX4 Gene Sequencing for Combined Pituitary Hormone Deficiency Type 4 (NGS) in UAE | 2,800 AED | DHA Licensed Diagnostics
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139).
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
- Clinical Guidance: Telephonic Post-Test Clinical Guidance from DHA-Licensed Consultant Medical Geneticists.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
- Full Legal Compliance: Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields.
Test Overview & Methodology
The LHX4 gene test uses Next-Generation Sequencing (NGS) to detect pathogenic variants in the LHX4 gene, which cause Combined Pituitary Hormone Deficiency Type 4 – a rare endocrine disorder characterized by insufficient production of multiple pituitary hormones. This test is essential for confirming the diagnosis, guiding lifelong hormone replacement, and enabling genetic counselling for families.
| Feature | Our LHX4 NGS Test | Standard Single-Gene Sanger Sequencing |
|---|---|---|
| Technology | NGS (Full Gene Coverage) | Sanger Sequencing (Limited Exons) |
| Turnaround Time | 3–4 Weeks | 6–8 Weeks |
| Sensitivity | >99.9% for SNVs/Indels | ~95% for known variant hotspots |
| Pre/Post Genetic Counselling | Included (Board-Certified Genetic Counsellor) | Often Not Included |
| Price (UAE) | 2,800 AED | 3,800–4,500 AED |
Physician Insight & Safety Protocols
“A definitive molecular diagnosis through LHX4 sequencing empowers families and clinicians to implement targeted surveillance and personalized endocrine management. This NGS-based test is the gold standard for establishing the genetic etiology of combined pituitary hormone deficiency.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Medication Advisory: Hormone Replacement Continuity
Important: Do not discontinue or modify prescribed hormone replacement therapy without explicit consultation with your managing endocrinologist. Abrupt cessation of pituitary-dependent hormones can precipitate life-threatening adrenal insufficiency.
Patient Safety Exclusion & Emergency Red Flags
- Exclusion Criteria: Active systemic infection, recent blood transfusion (<3 weeks), or inability to provide informed consent.
- ER Red Flags: Sudden severe headache, visual field defects, or signs of adrenal crisis (vomiting, hypotension, confusion) require immediate emergency care.
Patient FAQ & Clinical Guidance
1. What is the LHX4 gene test and who should consider it?
This precise NGS analysis detects LHX4 mutations causing combined pituitary hormone deficiency type 4, guiding lifelong treatment. It is recommended for children and adults presenting with growth failure, delayed puberty, central hypothyroidism, or adrenal insufficiency of unknown origin. It is also critical for family planning when a parent carries a known pathological variant.
2. How is the test performed and what sample is required?
A simple blood draw, FTA card spot, or extracted DNA is all that is needed, collected via VIP Mobile Phlebotomy. After scheduling, a certified phlebotomist visits your home (8 AM – 11 PM) using temperature-controlled cold-chain transport. No fasting required. Results are ready in 3–4 weeks.
3. Are the results confidential and will my insurance cover the cost?
Results are fully protected under UAE PDPL (Federal Decree-Law No. 45 of 2021), and we facilitate direct insurance verification via WhatsApp +971 54 548 8731. Genetic data is stored on secure, encrypted servers compliant with ISO 9001:2015. Most UAE insurance plans with genetic testing riders cover this test; we assist with pre-authorization.
UAE Regulatory & Data Privacy Adherence
Your Data, Protected by Law
DNA Labs UAE strictly adheres to Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All genetic and personal data are encrypted, access-controlled, and processed exclusively within our DHA-licensed facility (DHA License: 1143) located in Dubai Healthcare City.
Clinical & Logistical Metadata
| Test Name | LHX4 Gene Sequencing for Combined Pituitary Hormone Deficiency Type 4 (NGS) |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Peripheral Whole Blood, FTA Card Spot, or Extracted DNA |
| Methodology Used | Next-Generation Sequencing (NGS) – Full Gene Coverage |
| ICD-10-CM Code | E23.0 |
| LOINC Code | 21636-6 |
| DHA Facility License & Laboratory Address | DHA License: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians