Test Price
2,800 AED✅ Home Collection Available
IQSEC2 Gene X-Linked Intellectual Disability Type 1 (XLID) Genetic Test in UAE | 2,800 AED | DHA Licensed
Executive Summary & Core Metrics
- Diagnostic Sensitivity: 99.9% with ISO‑accredited NGS protocol
- Home Collection: ISO‑certified cold‑chain VIP mobile phlebotomy (8 AM – 11 PM)
- Post‑Test Support: Telephonic clinical guidance for result interpretation
- Insurance: Direct billing verification via WhatsApp +971 54 548 8731
- Price: 2,800 AED (includes pre‑test counselling and comprehensive report)
Test Overview & Methodology
This single‑gene NGS panel sequences the entire coding region of IQSEC2 to detect pathogenic, likely pathogenic, and variants of uncertain significance. It is indicated for males with unexplained moderate‑to‑severe intellectual disability, epilepsy, and stereotypic hand movements. The test uses high‑depth (>500×) next‑generation sequencing with Sanger fill‑in for confirmatory analysis and integrates current ACMG variant interpretation guidelines.
| Feature | Our Test (ISO Certified) | Closest Alternative |
|---|---|---|
| Technology | High‑depth NGS (>500×) with Sanger fill‑in | Research‑grade targeted Sanger sequencing (limited coverage) |
| Variant Interpretation | ACMG criteria + in‑house ClinVar/gnomAD databases | Basic database lookup without functional prediction |
| Reporting Turnaround | 3–4 weeks with geneticist‑signed report | 6–8 weeks, often lacking clinical interpretation |
| Pre‑Test Genetic Counselling | Mandatory pre‑test session (pedigree & consent) | Optional or not included |
Physician Insight & Safety Protocols
“Lina Osama Zaki Quteineh, Consultant Medical Genetics (DHA: 9294403) highlights: Interpretation of IQSEC2 results must be correlated with clinical phenotype, neuroimaging, and family history. A negative result does not exclude other X‑linked disorders. Early intervention therapies have been transformative when started by 18 months of age. Families should receive dedicated genetic counselling to understand recessive inheritance implications for female carriers.”
⚠️ Medication Safety Notice
Do not discontinue any prescribed antiepileptic, behavioural, or neurological medication without consulting your specialist. Abrupt withdrawal of anticonvulsants may provoke status epilepticus, which requires emergency medical care.
Exclusion Criteria & Emergency Red Flags
- Acute febrile illness or systemic infection – reschedule sampling until recovery.
- Inability to obtain informed consent from the legal guardian (mandatory for minors per Federal Decree‑Law No. 4 of 2016 on Medical Liability).
- Known haematological instability (e.g., severe thrombocytopenia) – consult the referral physician.
- Seek immediate ER attention if the patient develops: prolonged unresponsiveness, continuous seizure lasting >5 minutes, or breathing difficulties after sampling.
Patient FAQ & Clinical Guidance
1. Why is the IQSEC2 test recommended for my son with developmental delay?
A: IQSEC2 pathogenic variants are a known cause of X‑linked intellectual disability with epilepsy and autistic features. Confirming the diagnosis enables tailored early intervention and accurate family risk counselling. A negative result may still warrant broader genomic testing; always discuss reproductive options with a genetic counselor.
2. What does the 2,800 AED cost include and does insurance cover it?
A: The fee covers pre‑test genetic counseling, DNA extraction, NGS analysis, a detailed report signed by a clinical geneticist, and one post‑test teleconsultation. Insurance pre‑approval is verifiable via WhatsApp. Many UAE insurers cover genetic testing when a physician referral is provided; contact our team to verify your policy.
3. How is the sample collected and how do I ensure it remains stable for 3–4 weeks?
A: A DHA‑licensed phlebotomist performs home collection using a cold‑chain kit. DNA is extracted within 6 hours and stored at −20°C, preserving integrity regardless of the report turnaround time. If a blood spot FTA card is used, it must be dried and sent the same day; our courier team handles all logistics.
UAE Regulatory & Data Privacy Adherence
This service complies with Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All genetic data is stored on encrypted, on‑shore servers under DHA facility license 1143. Our processes are ISO 9001:2015 certified (Cert: INT/EGQ/2509DA/3139).
Clinical & Logistical Metadata
| Test Name | IQSEC2 Gene X‑Linked Intellectual Disability Type 1 (XLID) Genetic Test |
| Price (AED) | 2,800 |
| Turnaround Time | 3–4 weeks |
| Sample Type / Matrix | Peripheral whole blood (EDTA) or buccal swab. Cold‑chain home collection available. |
| Methodology Used | Next‑Generation Sequencing (NGS) of IQSEC2 coding region, with Sanger confirmation |
| ICD‑10‑CM Code | F78.9 |
| LOINC Code | 94490-0 |
| DHA Facility License & Laboratory Address | License: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
Contact: +971 54 548 8731 | WhatsApp
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Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians