Test Price
2,800 AED✅ Home Collection Available
IGF1R Gene Insulin-Like Growth Factor Resistance Genetic Test in UAE
Executive Summary & Core Metrics
- ✓Accuracy Guarantee: 99.9% diagnostic sensitivity via ISO 9001:2015 accredited NGS processing covering all exons and intron-exon boundaries.
- ✓Premium Logistics: VIP mobile phlebotomy with temperature-controlled cold-chain home collection available daily 8 AM to 11 PM across all UAE emirates.
- ✓Clinical Guidance: Post-test telephonic result interpretation with a DHA-licensed Consultant Medical Geneticist.
- ✓Insurance: Direct billing verification via WhatsApp at +971 54 548 8731.
Test Overview & Methodology
The IGF1R Gene Insulin-Like Growth Factor Resistance Genetic Test identifies pathogenic variants in the IGF1R gene that cause insulin-like growth factor-1 resistance, leading to severe pre- and postnatal growth retardation, microcephaly, and metabolic abnormalities. Using next-generation sequencing with deletion and duplication analysis, this test delivers a definitive molecular diagnosis for patients under investigation for syndromic short stature and informs targeted endocrine therapy decisions.
| Feature | Our Test (NGS Panel) | Closest Alternative (Sanger Sequencing) |
|---|---|---|
| Precision | >99.9% diagnostic sensitivity – all exons and flanking regions covered | ~95% for targeted point mutations only |
| Method | Next-generation sequencing with deletion and duplication analysis (CNV detection) | Single-gene Sanger sequencing; large rearrangements undetected |
| Turnaround Time | 3–4 weeks with fast-track option available | 4–6 weeks |
| Total Cost | 2,800 AED inclusive of pre- and post-test genetic counselling | 2,600–3,200 AED with additional counselling fees often separate |
Physician Insight & Safety Protocols
"The IGF1R gene test is a critical tool for differentiating primary growth factor resistance from secondary causes of short stature. A definitive molecular diagnosis empowers families and clinicians to pursue tailored growth hormone-sparing strategies. Always correlate genetic findings with auxological parameters and baseline IGF-1 levels before initiating therapy."
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
⚠️ Medication Advisory
Do not discontinue any prescribed growth hormone therapy, insulin, or corticosteroid regimen without explicit consultation with the managing endocrinologist. Abrupt cessation may precipitate metabolic decompensation.
Safety Exclusion Criteria & Emergency Red Flags
- Exclusion: Do not collect blood during acute febrile illness, while the patient is receiving high-dose corticosteroids, or in the presence of dehydration that may alter IGF-1 levels.
- Exclusion: This test is not validated for prenatal diagnosis; consult a Maternal-Fetal Medicine specialist for such indications.
- Emergency Red Flags: Seek immediate medical attention if the patient develops persistent vomiting, severe lethargy, altered consciousness, or fasting hypoglycemia.
Patient FAQ & Clinical Guidance
1. What is the purpose of the IGF1R gene test and what conditions does it identify?
This test detects disease-causing mutations in the IGF1R gene responsible for insulin-like growth factor-1 resistance. The condition manifests as severe growth restriction before and after birth, small head circumference, and metabolic disturbances. Establishing a genetic diagnosis enables targeted management and appropriate family counselling.
2. How is the sample collected and can home collection be arranged?
A standard peripheral whole blood sample is required. DNA Labs UAE offers VIP mobile phlebotomy with temperature-controlled cold-chain home collection available seven days a week from 8 AM to 11 PM across all emirates. Alternatively, samples may be provided at any of our patient service centres.
3. What is the turnaround time and total cost of the test?
The complete NGS analysis and clinical interpretation is reported within 3 to 4 weeks. The fixed all-inclusive price is 2,800 AED covering pre-test genetic counselling, sample processing, bioinformatic analysis, and a post-test telephonic consultation with a Consultant Medical Geneticist.
UAE Regulatory & Data Privacy Adherence
ISO 9001:2015 Certified – Cert No. INT/EGQ/2509DA/3139
All genetic data handling and processing strictly comply with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and patient consent procedures adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability.
Clinical & Logistical Metadata
| Test Name | IGF1R Gene Insulin-Like Growth Factor Resistance Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Peripheral Whole Blood — VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection |
| Methodology Used | Next-Generation Sequencing (NGS) with deletion and duplication analysis |
| ICD-10-CM Code | E34.3 (Short stature due to endocrine disorder) |
| LOINC Code | 21636-6 (Gene mutations found in Blood by Molecular genetics method) |
| DHA Facility License & Laboratory Address | DHA License No. 1143 — Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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