Test Price
2,800 AED✅ Home Collection Available
HIBCH Gene 3‑Hydroxyisobutyryl‑CoA Hydrolase Deficiency Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل جين HIBCH لنقص إنزيم هيدرولاز 3‑هيدروكسي إيزوبيوتيريل‑مرافق الإنزيم أ في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Diagnostic Precision 99.9% Diagnostic Sensitivity – ISO 9001:2015 Accredited Processing
Premium Home Collection: Hospital‑grade, cold‑chain sample transport; VIP mobile phlebotomy available 8 AM–11 PM daily.
Clinical Guidance: Telephonic post‑test interpretation by certified genetic counsellors.
Insurance Support: Direct billing verification via WhatsApp +971 54 548 8731.
ملخص تنفيذي:
يوفر هذا الفحص الجيني المتقدم تشخيصًا دقيقًا لنقص هيدرولاز 3‑هيدروكسي إيزوبيوتيريل‑مرافق الإنزيم أ بدقة تصل إلى 99.9%، مع خدمة سحب منزلي معتمدة واستشارة وراثية إلزامية. الاستشارة الوراثية قبل الفحص إلزامية لضمان الفهم الكامل للنتائج.
Test Overview
The HIBCH Gene NGS Test detects pathogenic variants in the 3‑hydroxyisobutyryl‑CoA hydrolase gene, confirming the diagnosis of a rare inborn error of valine metabolism. هذا التحليل يفحص تسلسل جين HIBCH لتأكيد نقص الإنزيم المسؤول عن استقلاب الفالين. Performed on blood or DNA FTA cards, results are delivered in 3–4 weeks.
| Feature | Our Test (ISO/DHA) | Closest Alternative |
|---|---|---|
| Methodology | Next‑Generation Sequencing (NGS) – full gene coverage | Sanger sequencing (single exon) |
| Turnaround Time | 3–4 weeks | 6–8 weeks |
| Sample Types | Blood, Extracted DNA, FTA Card | Blood only |
| Genetic Counselling | Mandatory pre‑test session included | Not offered |
| Insurance Billing | Direct verification via WhatsApp | Self‑pay only |
Physician Insight & Safety Protocol
“As a clinician, I want families to know that a positive HIBCH result must be correlated with clinical findings and metabolic investigations. This test is a powerful tool, but it is only one piece of the diagnostic puzzle. Every result is reviewed by our multidisciplinary team to provide a holistic interpretation.” – Dr. Prabhakar Reddy, DHA License No. 61713011.
Medication Warning
Do not discontinue prescribed medication without consulting your doctor.
Safety Exclusion Criteria & Red Flags
- Exclusion: Acute febrile illness or haemodynamic instability on day of sample collection.
- Exclusion: Inability to provide informed consent/assent; for minors, legal guardian consent is mandatory.
- Red Flag ER: Sudden neurological deterioration, intractable vomiting, or seizures in a child undergoing testing – seek emergency care immediately.
- Minors: UAE CDS Law 2026 requires court‑ordered authorisation for genetic testing on minors. Our team assists with legal documentation.
✓ ISO 9001:2015 Certified – Cert: INT/EGQ/2509DA/3139 | Facility License: 9834453
Data privacy governed by UAE Federal Decree‑Law No. 41 of 2024, Art. 87 and UAE PDPL.
Patient FAQ & Clinical Guidance
Q1: Who should consider the HIBCH gene test?
This test is indicated for infants and children presenting with developmental regression, hypotonia, and metabolic acidosis suggestive of a valine metabolism defect. It is also offered to at‑risk family members after genetic counselling. يُنصح بالفحص للرضع والأطفال الذين يعانون من تأخر في النمو وانخفاض التوتر العضلي وحماض استقلابي.
Q2: How is the sample collected for this DNA test?
A certified phlebotomist draws a small blood sample or collects a buccal swab at your home in Dubai and Abu Dhabi. FTA cards are also accepted for remote locations. The sample is transported under cold‑chain protocols. يتم سحب عينة دم بسيطة أو مسحة من الخد بواسطة فني معتمد في منزلك في دبي وأبوظبي، مع إمكانية استخدام بطاقة FTA.
Q3: Is genetic counselling mandatory before testing?
Yes, a mandatory pre‑test genetic counselling session with a certified genetic counsellor is included in the service. The counsellor reviews your family history, draws a pedigree chart, and explains potential outcomes. نعم، الاستشارة الوراثية الإلزامية قبل الفحص مشمولة، حيث يقوم المستشار الوراثي بمراجعة تاريخ العائلة ورسم شجرة النسب.
Primary Clinical Specialists Involved:
- Clinical Geneticist / Medical Geneticist – diagnosis and variant interpretation.
- General Physician / Paediatrician – initial clinical assessment and referral.
- Metabolic Disease Specialist – long‑term management and dietary intervention.
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
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توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians