Test Price
2,800 AED✅ Home Collection Available
FXYD2 Gene Hypomagnesemia Type 2 Genetic Test in UAE | AED 2800 | DHA Licensed
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily from 8 AM to 11 PM.
- Clinical Guidance: Telephonic Post-Test Clinical Guidance for personalised result interpretation and genetic counselling referral.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
- Regulatory Compliance: Full adherence to UAE PDPL and DHA health data protection standards.
Test Overview & Methodology
This targeted genetic test provides comprehensive analysis of the FXYD2 gene responsible for autosomal dominant renal hypomagnesemia type 2, enabling precise molecular diagnosis and guiding targeted clinical management. Our advanced NGS (Next Generation Sequencing) platform delivers superior coverage and analytical sensitivity compared to conventional single-gene Sanger assays, with complete gene analysis inclusive of all coding exons, splice junctions, and promoter regions.
| Feature | Our Test (NGS Full Gene) | Closest Alternative (Sanger Sequencing) |
|---|---|---|
| Coverage | Exons, splice sites, promoter – complete gene | Targeted exons only (often 80–90% coverage) |
| Sensitivity | >99.9% analytical sensitivity for SNVs & indels | ~98% for covered regions |
| Turnaround | 3–4 weeks with expedited options | 4–6 weeks typically |
| Post-Test Support | Telephonic interpretation & genetic counselling referral | Report only |
Physician Insight & Safety Protocols
Clinical Insight from Lina Osama Zaki Quteineh, Consultant Medical Genetics (DHA ID: 9294403): "This NGS test offers high clinical utility for identifying pathogenic FXYD2 variants, but it is essential to correlate findings with serum magnesium, urinary magnesium excretion, renal ultrasound, and a detailed family pedigree. I strongly recommend pre- and post-test genetic counselling to ensure informed decision-making and appropriate clinical integration."
Advisory & Safety Protocols
⚠️ Medication Advisory: Do not discontinue any prescribed medication, including magnesium supplements, diuretics, or any renal therapy, without prior consultation with your treating physician. This test is a diagnostic aid and should not be the sole basis for therapeutic adjustment.
Exclusion Criteria & Emergency Red Flags
Clinical Exclusion Criteria
- Inadequate sample (insufficient DNA, clotted, or hemolysed blood) – recollection will be requested.
- Recent allogeneic blood transfusion (within 2 weeks) may interfere with germline DNA analysis.
- Critical Emergency Warning: If the patient experiences severe hypomagnesemia symptoms – tetany, seizures, cardiac arrhythmias – immediately call emergency services (998) or visit the nearest Emergency Department.
- Persistent muscle cramps, confusion, or ECG changes require urgent clinical evaluation.
Patient FAQ & Clinical Guidance
1. What does the FXYD2 genetic test detect and how accurate is the NGS method?
This test detects mutations in the FXYD2 gene causing autosomal dominant renal hypomagnesemia type 2 with 99.9% analytical sensitivity. The NGS platform sequences all coding exons, splice junctions, and regulatory regions, identifying single-nucleotide variants, small insertions, deletions, and copy-number changes. Clinical validation confirms that the assay’s sensitivity exceeds 99.9% for the targeted coding regions, making it the most robust non-invasive molecular diagnostic tool for this rare metabolic disorder.
2. How is the home blood collection process conducted and what are the pre-requirements?
Our DHA-licensed phlebotomist collects a blood sample in a DNA-stabilizing tube, requiring no fasting and a prior genetic counselling session. Once you book via WhatsApp (+971 54 548 8731), a certified professional arrives at your home between 8 AM and 11 PM with a temperature-controlled kit. The only pre-requisite is a detailed clinical history and a pedigree chart drawn during a genetic counselling consultation (provided free of charge). Samples can also be submitted as FTA card or extracted DNA if already available.
3. What is the turnaround time for results and how will I receive them?
Results are delivered within 3 to 4 weeks via secure encrypted email and telephonic interpretation by a clinical expert. The final report includes variant classification according to ACMG guidelines, zygosity, and a clinical correlation summary. An appointment with a consultant geneticist or nephrologist can be arranged upon request. All data handling complies with UAE PDPL and ISO 9001:2015 confidentiality standards.
UAE Regulatory & Data Privacy Adherence
Your Data Security & Clinical Safety:
- Data Protection: Fully compliant with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) for all genomic and clinical data processing.
- Health Information Governance: Adheres to Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields.
- Medical Liability & Patient Safety: All clinical testing and patient consent protocols follow Federal Decree-Law No. 4 of 2016 on Medical Liability.
- Facility Accreditation: DNA Labs UAE operates under DHA Facility License Number 1143.
Clinical & Logistical Metadata
| Test Name | FXYD2 Gene Hypomagnesemia Type 2 Genetic Test |
| Price (AED) | 2,800 |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type / Matrix | Whole Blood (EDTA) / DNA FTA Card / Extracted DNA |
| Methodology Used | Next Generation Sequencing (NGS) – Full Gene Coverage |
| ICD-10-CM Code | E83.42, N25.8 |
| LOINC Code | 104020-1 |
| DHA Facility License & Address | License: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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All reports reviewed by DHA-Certified physicians