Test Price
2,800 AED✅ Home Collection Available
FKRP Gene Limb‑Girdle Muscular Dystrophy, Autosomal Recessive Type 2I Genetic Test in UAE | 2800 AED | DNA Labs UAE
Executive Summary & Core Metrics
Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 15189 & ISO 9001:2015 accredited genomic processing.
Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
Clinical Guidance: Complimentary telephonic post‑test clinical interpretation by our DHA‑licensed medical team.
Insurance: Direct billing verification — send your Emirates ID & policy number via WhatsApp +971 54 548 8731.
Executive Summary (Arabic): يوفر تحليل الجين FKRP بتقنية التسلسل من الجيل التالي تشخيصاً جينياً دقيقاً لضمور العضلات الحزامية الطرفي النمط 2I بمطابقة تامة لأحدث توجيهات هيئة الصحة بدبي. يتم تنفيذ الفحص في مختبر حاصل على شهادات الآيزو العالمية مع إمكانية السحب المنزلي المعتمد والاستشارات الوراثية ما بعد النتيجة.
Test Overview & Methodology
The FKRP gene test is a comprehensive next‑generation sequencing (NGS) assay that analyses the entire coding region of the fukutin‑related protein gene to confirm a clinical diagnosis of limb‑girdle muscular dystrophy type 2I (LGMD2I). This autosomal recessive condition causes progressive muscle weakness, and early genetic confirmation is essential for precise management, family planning, and access to emerging therapies.
This NGS-based test covers all exons and splice sites, providing a diagnostic yield exceeding 99% for FKRP-related LGMD2I. It is the gold standard for de novo or suspected cases, enabling accurate carrier testing and prenatal diagnosis.
| Feature | Our Test – FKRP NGS Full Gene Sequencing | Closest Alternative – Targeted Variant Analysis |
|---|---|---|
| Methodology | Next‑Generation Sequencing (NGS) – covers all exons & splice sites | Sanger sequencing of a single known familial variant only |
| Diagnostic Yield | >99% for FKRP‑related LGMD2I | Limited to one mutation; may miss compound heterozygosity or novel variants |
| Turnaround Time | 3–4 Weeks | 2–3 Weeks (dependent on index case knowledge) |
| Clinical Utility | Gold‑standard for de novo or suspected LGMD2I; enables accurate carrier testing & prenatal diagnosis | Appropriate only if familial mutation is already known |
Physician Insight & Safety Protocols
"As a Consultant Medical Genetics, I recognise the significant impact that a precise genetic diagnosis can have on the management of progressive muscle disorders. This FKRP NGS test offers families the molecular clarity needed to navigate treatment paths, clinical trial eligibility, and reproductive counselling. Results must always be correlated with complete clinical and family history."
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA License: 9294403
Advisory – Medication & Treatment Continuity
⚠️ Important Notice
Do not discontinue prescribed medication or modify your treatment plan without consulting your treating physician. This genetic test is an elective diagnostic tool and does not replace immediate medical advice.
Exclusion Criteria & Emergency Red Flags
- Acute Medical Emergency: If you are experiencing rapid loss of ambulation, acute respiratory distress, or cardiac symptoms (palpitations, syncope), proceed directly to the nearest ER. Genetic testing is not appropriate during an acute clinical crisis.
- Severe Neurological Deterioration Requiring Hospitalisation: This test must be deferred until the patient is medically stable.
- Uncontrolled Seizures or Aspiration Pneumonia: These conditions require urgent intervention; genetic testing can be performed after stabilisation.
- Red Flag Symptoms: Sudden inability to walk, choking, severe muscle pain with dark urine (risk of rhabdomyolysis), or new‑onset cardiac arrhythmia warrant immediate emergency evaluation, not elective genetic sampling.
Patient FAQ & Clinical Guidance
1. What is the FKRP gene test and how is it performed?
The FKRP gene next-generation sequencing test completely screens the entire fukutin-related protein gene to diagnose limb-girdle muscular dystrophy type 2I. A simple blood draw or dried blood spot is collected, and all coding exons are analysed using high‑throughput NGS technology, achieving over 99.9% diagnostic sensitivity.
2. How long does it take to receive results and are they clinically reliable?
Results are typically delivered within 3 to 4 weeks from sample receipt, with 99.9% diagnostic accuracy validated through ISO 9001:2015 and ISO 15189 accredited genomic pipelines. Each variant is confirmed by orthogonal methods, ensuring the highest clinical reliability for patient management.
3. Does health insurance in the UAE cover the FKRP genetic test?
Many UAE insurance plans cover medically necessary single‑gene tests when accompanied by a neurologist’s referral and pre‑authorisation. We provide direct billing verification via WhatsApp at +971 54 548 8731. Our patient support team will obtain instant approval confirmation so you can proceed without upfront payment worries.
UAE Regulatory & Data Privacy Adherence
Regulatory Compliance: All genetic testing procedures at DNA Labs UAE strictly follow Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Patient consent and clinical safety protocols are governed by Federal Decree-Law No. 4 of 2016 on Medical Liability. Your genomic data is encrypted and handled with the highest confidentiality standards.
Clinical & Logistical Metadata
| Test Name | FKRP Gene Limb‑Girdle Muscular Dystrophy, Autosomal Recessive Type 2I Genetic Test (NGS Full Gene Sequencing) |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Peripheral Whole Blood or Dried Blood Spot (VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily 8 AM – 11 PM) |
| Methodology Used | Next‑Generation Sequencing (NGS) – full exon and splice site analysis |
| ICD-10-CM Code | G71.0 (Muscular dystrophy) |
| LOINC Code | 98116-2 (FKRP gene mutation analysis in Blood or Tissue by Molecular genetics method) |
| DHA Facility License & Laboratory Address | DHA Facility License: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | Corporate Lab: DNA Labs UAE |
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