Test Price
2,800 AED✅ Home Collection Available
CDC73 Gene (Hyperparathyroidism-Jaw Tumor Syndrome) NGS Test | 2800 AED | DNA Labs UAE
Executive Summary & Core Metrics
✓ 99.9% diagnostic sensitivity achieved through ISO 9001:2015 accredited processing at DNA Labs UAE, ensuring precise germline mutation detection in the CDC73 tumour-suppressor gene.
✓ Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily from 8 AM to 11 PM across Dubai and the Northern Emirates.
✓ Clinical Guidance: Telephonic post-test result interpretation provided by a board-certified Consultant Medical Genetics specialist.
✓ Insurance: Direct billing verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
This Next Generation Sequencing (NGS) assay detects germline mutations in the CDC73 tumour-suppressor gene, definitively diagnosing Hyperparathyroidism-Jaw Tumor Syndrome (HPT-JT) and familial isolated hyperparathyroidism. The test provides a risk-stratified pathway to early tumour surveillance and personalised endocrine care, enabling informed clinical decisions for patients and their families.
| Feature | Our CDC73 NGS Test | Closest Alternative (Sanger Sequencing) |
|---|---|---|
| Coverage | Full gene, all exons + flanking intronic regions | Single-exon or hotspot analysis only |
| Diagnostic Sensitivity | 99.9% | ~98% (misses deep intronic/CNV) |
| Turnaround Time | 3–4 Weeks | 4–6 Weeks (often sent abroad) |
| UAE Regulatory Compliance | DHA-Licensed, ISO 9001:2015, PDPL-compliant | May lack local accreditation |
Physician Insight & Safety Protocols
"A germline CDC73 alteration carries profound implications for lifelong cancer surveillance and family screening. I emphasise that this molecular result must be contextualised within the full pedigree and clinical phenotype. Never interpret a genomic finding in isolation—always pair it with a comprehensive genetic counselling session to guide meaningful preventive action."
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Medication & Clinical Advisory
Critical Medication Warning
Do not discontinue prescribed medication without consulting your doctor. Abruptly stopping calcium-lowering agents, vitamin D analogues, or other endocrine therapies may precipitate life-threatening hypercalcemia or cardiac arrhythmia. All treatment adjustments must be medically supervised.
Exclusion Criteria & Emergency Red Flags
- Genetic testing for minors requires mandatory legal guardian consent and pre-test genetic counselling in accordance with Federal Decree-Law No. 4 of 2016 on Medical Liability.
- Sample collection cannot proceed if the patient exhibits acute hypercalcemic crisis (corrected calcium >3.5 mmol/L) – clinical stabilisation must take priority.
- Seek emergency care immediately if you develop sudden bone pain, renal colic, profound muscle weakness, confusion, or cardiac palpitations.
Patient FAQ & Clinical Guidance
1. What does a positive CDC73 mutation result mean for my health?
A positive result confirms a hereditary predisposition to hyperparathyroidism and jaw tumours, requiring lifelong clinical surveillance including annual calcium and PTH measurements, parathyroid imaging, and dental panoramic radiographs starting in adolescence. Family members should also be offered predictive testing.
2. How is the sample collected and does it require any preparation?
A simple blood draw via peripheral venipuncture is collected at your preferred location through our VIP Mobile Phlebotomy service. No fasting or medication adjustment is required. The sample is transported under temperature-controlled cold-chain conditions to our ISO-accredited laboratory in Dubai Healthcare City.
3. Can I use insurance and how quickly will I receive my report?
Direct insurance billing eligibility is verified instantly via WhatsApp at +971 54 548 8731. The final certified genetic report is delivered electronically within 3 to 4 weeks from sample receipt, accompanied by a telephonic consultation with our genetics specialist.
4. Will my genetic data remain private and secure?
Yes. DNA Labs UAE complies fully with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Your genomic information is encrypted, access-restricted, and never shared without your explicit written consent.
UAE Regulatory & Data Privacy Adherence
Regulatory Framework: This test is performed under the regulatory oversight of the Dubai Health Authority (DHA) and adheres to Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and patient consent are governed by Federal Decree-Law No. 4 of 2016 on Medical Liability.
Quality Certification: ISO 9001:2015 — Certificate No. INT/EGQ/2509DA/3139.
Corporate Laboratory Branding: DNA Labs UAE.
Clinical & Logistical Metadata
| Test Name | CDC73 Gene (Hyperparathyroidism-Jaw Tumor Syndrome) NGS Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Peripheral whole blood, serum, or plasma — VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM) |
| Methodology Used | Next Generation Sequencing (NGS) — Full gene, all exons + flanking intronic regions |
| ICD-10-CM Code | E21.0 (Primary hyperparathyroidism) |
| LOINC Code | 82128-6 (CDC73 gene mutation detection in Blood or Tissue by Sequencing) |
| DHA Facility License & Laboratory Address | DHA Facility License Number: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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