Test Price
2,800 AED✅ Home Collection Available
AP4M1 Gene Microcephaly Genetic Test | 2,800 AED | DNA Labs UAE
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% diagnostic sensitivity via ISO‑accredited NGS processing covering all coding exons and splice junctions.
- Premium Logistics: VIP mobile phlebotomy and temperature‑controlled cold‑chain home collection available daily from 8 AM to 11 PM.
- Clinical Guidance: Complimentary telephonic post‑test interpretation with a consultant medical genetics specialist.
- Insurance: Direct billing verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The AP4M1 Gene Microcephaly Genetic Test employs high‑depth next‑generation sequencing (NGS) to interrogate the entire coding region and conserved splice sites of the AP4M1 gene. Pathogenic variants in this gene cause autosomal recessive microcephaly and associated neurodevelopmental phenotypes. The assay delivers 99.9% sensitivity for single‑nucleotide variants and small insertions/deletions, with confirmatory Sanger sequencing performed for all reported findings.
| Feature | DNA Labs UAE Test | Closest Alternative |
|---|---|---|
| Precision | NGS – whole exon + splice sites (99.9% sensitivity) |
Sanger sequencing (single variant) lower sensitivity |
| Methodology | Illumina® platform with clinical‑grade bioinformatics pipeline | PCR + fragment analysis |
| Turnaround Time | 3–4 Weeks | 4–6 Weeks |
Physician Insight & Safety Protocols
“Molecular confirmation of AP4M1‑related microcephaly provides families with a precise genetic diagnosis, enabling targeted reproductive counseling and access to early neurodevelopmental therapies. Because this is an autosomal recessive condition, carrier testing for both parents and cascade screening of at‑risk relatives is strongly recommended. Results must be integrated with head circumference trajectories, brain MRI findings, and a three‑generation family pedigree.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics (DHA Registration ID: 9294403)
⚠️ Advisory Notice: Medication and Clinical Guidance
Do not discontinue, adjust, or introduce any prescribed medication—including antiepileptic agents, hormonal therapies, or nutritional supplements—without explicit direction from the treating physician, irrespective of the genetic test outcome. Abrupt changes may precipitate serious adverse events.
🚨 Patient Safety – Exclusion Criteria & Emergency Red Flags
- Exclusion: Active febrile illness, severe thrombocytopenia, or inability to provide the minimum sample (one drop of blood on FTA card).
- Red Flag: New‑onset seizures, apnea, or loss of consciousness while awaiting results—proceed immediately to the nearest Emergency Department.
- Red Flag: Sudden deterioration in motor skills or recurrent vomiting requires urgent neurological assessment; do not delay clinical evaluation for test results.
Patient FAQ & Clinical Guidance
1. What does the AP4M1 NGS test reveal about my child’s microcephaly?
This test detects pathogenic variants in the AP4M1 gene responsible for autosomal recessive microcephaly, providing a confirmed genetic diagnosis that guides prognosis, reproductive planning, and eligibility for early intervention programs. A negative result does not rule out other genetic causes of microcephaly.
2. How is the sample collected, and is the procedure safe for my infant?
A certified pediatric phlebotomist collects a few drops of blood via a painless heel‑prick onto a sterile FTA card or through a standard venous draw. The procedure is performed in your home under strict sterile conditions and temperature‑controlled cold‑chain transport. Venipuncture is contraindicated if the child has a bleeding disorder or active infection at the puncture site.
3. When will I receive the results, and how will they be explained to me?
Your comprehensive clinical report is issued within 3–4 weeks. A complimentary teleconsultation with our consultant medical genetics specialist is scheduled to review the findings, discuss inheritance patterns, and outline recommended follow‑up steps tailored to your family’s needs.
UAE Regulatory & Data Privacy Adherence
Data Protection & Health Information Governance
All genetic data processed through this test is handled in strict compliance with Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and informed consent protocols follow Federal Decree‑Law No. 4 of 2016 on Medical Liability. DNA Labs UAE is ISO 9001:2015 certified (Cert: INT/EGQ/2509DA/3139) and maintains rigorous data‑encryption and access‑control standards.
Clinical & Logistical Metadata
| Test Name | AP4M1 Gene Microcephaly Genetic Test |
| Price (AED) | 2,800 |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Peripheral Blood (FTA Card or Venous Draw) |
| Methodology Used | Next‑Generation Sequencing (NGS) – Whole Exon + Splice Site Analysis |
| ICD-10-CM Code | Q02 |
| LOINC Code | 94233-2 |
| DHA Facility License & Laboratory Address | DHA License: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians