Test Price
2,800 AED✅ Home Collection Available
KISS1 Gene Hypogonadotropic Hypogonadism Genetic Test in UAE | AED 2800 | DHA Licensed
This NGS-based genetic test sequences the entire KISS1 gene to diagnose hypogonadotropic hypogonadism with 99.9% diagnostic sensitivity under ISO 9001:2015 accredited processing.
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
- Clinical Guidance: Telephonic Post-Test Clinical Guidance by DHA-licensed Consultant Medical Genetics for result interpretation.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
This advanced NGS test comprehensively sequences the entire coding region of the KISS1 gene to identify pathogenic variants linked to hypogonadotropic hypogonadism, a condition causing absent or delayed puberty and infertility. It provides a definitive molecular diagnosis, empowering personalized treatment with gonadotropin therapy or assisted reproduction.
| Feature | Our KISS1 NGS Test | Standard Hormonal Assay |
|---|---|---|
| Methodology | Next‑Generation Sequencing (NGS) – full gene analysis | Immunoassay for FSH/LH/estradiol |
| Coverage | >99.9% of coding region + exon–intron boundaries | Circulating hormone levels (functional snapshot) |
| Turnaround Time | 3‑4 Weeks | 1‑2 Days |
| Clinical Utility | Definitive genetic diagnosis, familial cascade testing, personalized therapy planning | Indirect biochemical assessment; often requires repeated testing |
Physician Insight & Safety Protocols
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Advisory
⚠️ Do not discontinue any prescribed medication without consulting your doctor.
Exclusion Criteria & Red Flags
- Active systemic infection or febrile illness precluding blood draw.
- Individuals on anticoagulants that cannot be briefly paused under medical supervision.
- ER Red Flags: sudden severe headache, acute vision loss or visual field cut, unexplained hypotension or loss of consciousness—seek immediate emergency care.
Patient FAQ & Clinical Guidance
1. What symptoms suggest a need for KISS1 gene testing?
Direct Answer: Persistent delayed puberty, absent menstruation, infertility of pituitary origin, anosmia, or a family history of hypogonadotropic hypogonadism are key indicators for testing.
Clinical scenarios include isolated GnRH deficiency, normosmic idiopathic hypogonadotropic hypogonadism, or combined pituitary hormone deficiencies. The test uncovers variants in KISS1 that disrupt pubertal onset and reproductive function, helping differentiate from constitutional delay or structural anomalies.
2. How is the sample collected and what preparation is required?
Direct Answer: A single blood draw (3‑5 mL in EDTA tube) or dried blood spot on FTA card requires no fasting; a prior genetic counseling session documents the family pedigree.
Our VIP mobile phlebotomy team collects from home/office using ISO‑certified cold‑chain transport. Pre‑test information should include clinical history of pubertal development, previous hormonal assays, and any relevant family history. Discontinue anticoagulants only under medical advice 48 hours before sample collection.
3. What do the results mean and who interprets them?
Direct Answer: The report identifies pathogenic/likely pathogenic variants, variants of uncertain significance, or no relevant variant, and is interpreted by a board‑certified clinical geneticist.
A positive result confirms the genetic form and enables targeted family screening. Variants of uncertain significance may require periodic re‑analysis. Post‑test telephonic guidance with our DHA‑licensed Consultant Medical Genetics ensures clear understanding and connection to appropriate care. All data is protected under UAE PDPL and Federal Decree‑Law No. 45 of 2021.
UAE Regulatory & Data Privacy Adherence
Regulatory Compliance & Accreditation: This service is delivered under DHA Facility License 1143, Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE. All genetic testing complies with UAE Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and patient consent follow Federal Decree‑Law No. 4 of 2016 on Medical Liability. The laboratory operates under ISO 9001:2015 accreditation.
Clinical & Logistical Metadata
| Test Name | KISS1 Gene Hypogonadotropic Hypogonadism Genetic Test |
| Price (AED) | 2800 |
| Turnaround Time | 3‑4 Weeks |
| Sample Type / Matrix | Peripheral whole blood (EDTA) or Dried Blood Spot (FTA card) |
| Methodology Used | Next‑Generation Sequencing (NGS) |
| ICD-10-CM Code | E23.0, E29.1, Z15.89 |
| LOINC Code | 78824-5 |
| DHA Facility License & Laboratory Address | 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians