Test Price
2,800 AED✅ Home Collection Available
AURKC Gene SPGF5 Genetic Test in UAE | 2800 AED | DHA Licensed
Executive Summary & Core Metrics
- Diagnostic Accuracy: 99.9% sensitivity for all known pathogenic AURKC variants via ISO 9001:2015 certified NGS.
- Sample Collection: VIP mobile phlebotomy with temperature-controlled cold-chain logistics, available daily 8 AM – 11 PM.
- Clinical Support: Mandatory pre-test genetic counseling and telephonic post-test result interpretation included.
- Insurance Verification: Direct billing check via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The AURKC Gene SPGF5 Genetic Test utilizes next-generation sequencing (NGS) to detect pathogenic and likely pathogenic variants in the AURKC gene associated with spermatogenic failure type 5 (SPGF5). This test provides definitive molecular diagnosis for males presenting with primary infertility due to severe oligospermia or azoospermia, enabling accurate reproductive risk assessment and guided family planning.
| Feature | AURKC NGS Test | Single-Gene PCR Panel |
|---|---|---|
| Methodology | Next-Generation Sequencing (full gene) | Targeted mutation panel |
| Detection Rate | >99.9% for all known pathogenic variants | <85% (misses novel and rare variants) |
| Turnaround Time | 3–4 weeks | 5–8 weeks |
| Regulatory Compliance | DHA, MOHAP, UAE PDPL | Variable adherence |
Physician Insight & Safety Protocols
“As a DHA-licensed consultant medical geneticist, I confirm that a positive AURKC SPGF5 mutation result establishes the molecular etiology of spermatogenic failure. This finding must always be integrated with semen parameters, hormonal assays, and detailed family pedigree analysis. I understand the emotional complexity of infertility; please never interpret genetic results in isolation. Your multidisciplinary care team will ensure every implication is addressed with compassion and scientific rigor.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Advisory Notice
⚠ Important Clinical Advisory
Do not discontinue any prescribed fertility medication or treatment without consulting your physician. This genetic test provides diagnostic information and does not replace ongoing medical care. Always discuss potential changes in therapy with your treating specialist.
Exclusion Criteria & Emergency Red Flags
- Exclusion: Individuals unable to provide informed consent; minors without legal guardian authorization; active systemic infection compromising sample quality.
- Emergency Red Flags: If you experience acute psychological distress or suicidal ideation following result disclosure, call 998 immediately or contact our crisis referral hotline.
Patient FAQ & Clinical Guidance
1. What is the AURKC Gene SPGF5 Genetic Test used for?
This test detects pathogenic mutations in the AURKC gene responsible for spermatogenic failure type 5 (SPGF5), a common autosomal recessive cause of male infertility in certain populations. It is indicated for men with unexplained azoospermia or severe oligospermia, couples with a family history of SPGF5, and carrier screening in consanguineous families. Pre-test genetic counseling is mandatory under DHA guidelines to review autosomal recessive inheritance patterns and implications for extended family members.
2. How is the sample collected and how long do results take?
A peripheral whole blood sample (EDTA tube), extracted genomic DNA, or a dried blood spot on an FTA card is accepted. Our VIP mobile phlebotomy team performs home collection with ISO-certified cold-chain transport from 8 AM to 11 PM daily. Results are delivered within 3–4 weeks via a secure digital platform, followed by a telephonic consultation with a genetic counselor to explain findings and next steps.
3. Is genetic counseling mandatory before taking this test?
Yes, a mandatory pre-test genetic counseling session is required. A certified genetic counselor will construct a three-generation pedigree, explain the autosomal recessive inheritance of SPGF5, discuss recurrence risks, and outline reproductive options including preimplantation genetic testing. This session meets DHA regulatory standards and is included in the service fee. A bilingual summary report is provided for your records.
UAE Regulatory & Data Privacy Adherence
DNA Labs UAE strictly complies with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) for all genetic data handling, storage, and sharing. Clinical testing and patient consent procedures follow Federal Decree-Law No. 4 of 2016 on Medical Liability. Health information security is maintained in accordance with Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Your genetic data is encrypted, access-controlled, and never shared without explicit written consent.
Clinical & Logistical Metadata
| Test Name | AURKC Gene SPGF5 Genetic Test (NGS) |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 weeks |
| Sample Type / Matrix | Peripheral whole blood (EDTA), extracted genomic DNA, or FTA card |
| Methodology Used | Next-Generation Sequencing (full gene) |
| ICD-10-CM Code | N46.0, N46.8 |
| LOINC Code | 21636-6 |
| DHA Facility License & Address | License 1143 – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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