Pre-implantation Genetic Diagnosis (PGD) – Single Embryo Analysis in UAE | 3600 AED

Executive Summary & Core Metrics

Core Metrics

Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139).
Clinical Logistics: Hospital Extraction Only – Sample collection is conducted strictly within an accredited hospital facility; mobile home phlebotomy is disabled for safety.
Clinical Guidance: Complimentary Telephonic Post-Test Clinical Guidance to interpret results with a DHA-licensed specialist.
Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.

Test Overview & Methodology

Pre-implantation Genetic Diagnosis (PGD) for a single embryo is a sophisticated genetic screening performed on a trophectoderm biopsy during IVF, using Sanger sequencing to detect inherited disorders before embryo transfer. This test empowers couples with actionable genetic insights, minimizing the risk of transmitting serious monogenic conditions. The procedure is conducted under strict embryological oversight within a licensed IVF facility.

Feature	Our Test (PGD Single Embryo)	Closest Alternative (Conventional PGT-A)
Precision	Single-Gene Resolution via Sanger Sequencing; 99.9% accuracy for targeted mutations	Aneuploidy screening only; cannot pinpoint monogenic disorders
Methodology	Sanger Sequencing with confirmatory analysis	Next-Generation Sequencing (NGS) for chromosomal copy number
Turnaround Time	15–20 business days (expedited options available)	7–14 days
Clinical Applicability	Carriers of known single-gene defects, translocations	Routine IVF aneuploidy screening

Physician Insight & Safety Protocols

“Pre-implantation genetic diagnosis delivers exceptional precision for families with known inherited mutations. However, it must be integrated with comprehensive pre- and post-test genetic counseling to ensure informed decision-making. The test evaluates only the specific markers requested; it does not provide a full genomic health profile. Always review results with your fertility and genetics team before proceeding with embryo transfer.”

– Lina Osama Zaki Quteineh, Consultant Medical Genetics | DHA Registration ID: 9294403

Critical Medication Advisory

Do not alter or discontinue any prescribed ovarian stimulation or hormonal protocol without explicit guidance from your treating fertility physician. Abrupt changes may compromise IVF cycle outcomes and maternal well-being.

Exclusion Criteria & Emergency Red Flags

PGD must be ordered by a licensed fertility physician; not intended for pregnancy diagnosis or stand-alone surgical screening.
Active pelvic infection or severe ovarian hyperstimulation syndrome (OHSS) risk – defer until clinically resolved.
Known allergy to biopsy medium components – inform laboratory before the procedure.
Embryo with poor morphological grade that cannot sustain trophectoderm biopsy.
Emergency Red Flags: Severe abdominal pain, heavy vaginal bleeding, or fever within 48 hours post-biopsy requires immediate emergency care.

Patient FAQ & Clinical Guidance

1. What is the accuracy of PGD for a single embryo, and can it detect all genetic diseases?

Sanger sequencing guarantees 99.9% base-calling precision for the targeted mutation panel. However, it screens only the specific gene markers ordered by your physician; it does not perform a whole-genome analysis for unknown or unrelated variants.

2. How is the sample collected, and is it painful for the embryo or the mother?

A skilled embryologist gently removes a few trophectoderm cells from a day-5 blastocyst. The embryo remains viable, and the mother experiences no additional discomfort beyond the standard IVF retrieval procedure.

3. Will my insurance cover this PGD, and what if the result is abnormal?

Many UAE insurers now cover medically indicated PGD. Our team verifies your policy via WhatsApp and provides a direct billing statement. If an abnormal result is identified, complimentary genetic counseling is arranged to discuss implications and next steps.

UAE Regulatory & Data Privacy Adherence

Data Protection & Confidentiality: All genetic data is processed in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Patient consent and clinical safety protocols adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability.

Laboratory Accreditation: DNA Labs UAE operates under DHA Facility License No. 1143 and maintains ISO 9001:2015 certification (Cert: INT/EGQ/2509DA/3139) for diagnostic quality management.

Clinical & Logistical Metadata

Test Name	Pre-implantation Genetic Diagnosis (PGD) – Single Embryo Analysis
Price (AED)	3,600 AED
Turnaround Time	15–20 business days (expedited options available)
Sample Type / Matrix	Trophectoderm biopsy (day-5 blastocyst) – Hospital extraction only
Methodology Used	Sanger Sequencing with confirmatory analysis
ICD-10-CM Code	Z31.49
LOINC Code	90556-9
DHA Facility License & Laboratory Address	DHA License No. 1143 \| Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE \| DNA Labs UAE