Test Price
2,800 AED✅ Home Collection Available
CYP2C19 Genotyping (Drug Metabolism) Genetic Test in Dubai, UAE
Executive Summary & Core Metrics
- Diagnostic Accuracy: 99.9% specificity and sensitivity via ISO-accredited Next Generation Sequencing.
- Logistics Excellence: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection, available daily from 8 AM to 11 PM.
- Clinical Guidance: Post-test teleconsultation with a clinical geneticist for result interpretation and pharmacogenomic action planning.
- Insurance Verification: Direct billing support via WhatsApp at +971 54 548 8731.
Test Overview & Methodology
The CYP2C19 Genotyping Genetic Test identifies clinically significant variants (*2, *3, *17 and other star alleles) in the CYP2C19 gene. This gene encodes a key enzyme in the cytochrome P450 system, responsible for metabolizing a wide range of drugs including clopidogrel, proton pump inhibitors (PPIs), and selective serotonin reuptake inhibitors (SSRIs). Detecting a patient's metabolizer phenotype—poor, intermediate, extensive, or ultrarapid—allows physicians to optimize drug selection and dosing, reducing the risk of adverse events or therapeutic failure. Our laboratory employs full-gene Next Generation Sequencing to capture common and rare mutations, ensuring comprehensive pharmacogenomic insight.
| Feature | Our Test (NGS Full Gene) | Standard PCR-Based Tests |
|---|---|---|
| Methodology | Next Generation Sequencing (Full Gene) | Real-time PCR (Limited Variants) |
| Coverage | All clinically relevant star alleles (*2, *3, *17) & rare variants | Only common variants, risk of missing rare mutations |
| Turnaround Time | 3–4 Weeks (Comprehensive Analysis & Validation) | 1–2 Weeks (Limited Scope) |
Physician Insight & Safety Protocols
"Pharmacogenomic testing provides a powerful data point for precision prescribing. However, the CYP2C19 genotype is one piece of a complex puzzle involving drug-drug interactions, renal function, and patient adherence. A negative result does not guarantee therapeutic success, and a poor metabolizer phenotype requires careful alternative strategy planning. Interpretation by a qualified clinical geneticist is essential for translating these genomic insights into safe, personalized therapeutic regimens." — Lina Osama Zaki Quteineh | Consultant Medical Genetics | DHA Registration ID: 9294403
Advisory Points
Clinical Advisory: Do not discontinue, alter, or adjust dosages of any prescribed medication solely based on the results of this genetic test. This report is an adjunctive tool for your treating physician. All changes to pharmacotherapy must be supervised by the prescribing doctor.
Patient Exclusion Criteria & Emergency Red Flags
- Patients with active bleeding disorders or severe thrombocytopenia must postpone venipuncture until medically cleared.
- Known hypersensitivity to antiseptics or latex; alternative collection materials will be used if notified in advance.
- If you experience sudden severe symptoms (chest pain, difficulty breathing, uncontrolled bleeding) unrelated to test preparation, seek emergency care immediately — do not wait for appointment.
- Fasting is not required, but inform the phlebotomist of all current medications and supplements.
Patient FAQ & Clinical Guidance
1. What does a CYP2C19 poor metabolizer result mean?
A poor metabolizer result indicates that you carry two non-functional copies of the CYP2C19 gene, leading to a significant reduction in enzyme activity. This can increase the risk of adverse events or reduced efficacy with standard doses of drugs that require CYP2C19 for activation, such as clopidogrel. Your physician may consider alternative therapies or dose adjustments.
2. Is home blood collection safe for this genetic test?
Yes. Our DHA-licensed mobile phlebotomists perform hospital-grade home collection. The sample is immediately placed in a temperature-controlled cold-chain transport kit to maintain DNA integrity. This VIP service is available daily from 8 AM to 11 PM for standard blood draws.
3. Do I need genetic counseling before this test?
Pre-test genetic counseling is recommended to understand the scope of pharmacogenomic testing and its impact on family members. Our package includes a mandatory teleconsultation with a genetics expert to review your medication and family history, ensuring informed consent and accurate result interpretation.
UAE Regulatory & Data Privacy Adherence
DNA Labs UAE strictly complies with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All clinical safety protocols are governed by Federal Decree-Law No. 4 of 2016 on Medical Liability. Genetic data is encrypted, access-controlled, and processed within our DHA-licensed facility. We adhere to global standards for patient confidentiality and data security.
Clinical & Logistical Metadata
| Test Name | CYP2C19 Genotyping (Drug Metabolism) Genetic Test |
| Price (AED) | 2,800 |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Whole Blood (EDTA), Extracted DNA, or Dried Blood Spot (FTA Card) |
| Methodology Used | Next Generation Sequencing (NGS) – Full Gene Coverage |
| ICD-10-CM Code | Z13.81, Z84.8 |
| LOINC Code | 81803-3 |
| DHA Facility License & Lab Address | License # 1143, Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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All reports reviewed by DHA-Certified physicians