Test Price
1,000 AED✅ Home Collection Available
EWSR1 Gene Rearrangement (Ewing Sarcoma) Test in UAE | 1,000 AED | DHA Licensed
Executive Summary & Core Metrics
🔬 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing
📦 Secure Medical Courier Solid Tissue Specimen Retrieval
📞 Telephonic Post-Test Clinical Guidance on Result Interpretation
💳 Direct Billing Verification via WhatsApp: +971 54 548 8731
Test Overview & Methodology
The EWSR1 Gene Rearrangement (Ewing Sarcoma) Test uses Fluorescence In‑Situ Hybridization (FISH) on tumor tissue to detect hallmark chromosomal translocations—most commonly t(11;22)(q24;q12)—enabling definitive molecular confirmation of Ewing sarcoma family tumors and guiding targeted therapy decisions.
This FISH‑based assay employs break‑apart probes targeting the EWSR1 locus at 22q12, providing high sensitivity and specificity for the detection of rearrangements that define Ewing sarcoma and related small round blue cell tumors. The result informs clinical management, including chemotherapy protocols and clinical trial eligibility.
| Feature | Our EWSR1 FISH Test | Closest Alternative (RT‑PCR / IHC) |
|---|---|---|
| Diagnostic Precision | 98% sensitivity, 100% specificity | ~95% sensitivity, 98% specificity |
| Methodology | FISH (break‑apart probe) on FFPE tissue | RT‑PCR (requires fresh/frozen tissue) / IHC for CD99 |
| Turnaround Time | 7–8 working days | 10–14 days (external lab) |
| Regulatory Compliance | Full (ISO 9001:2015, DHA Licensed) | Varies by provider |
Physician Insight & Safety Protocols
“As a Specialist in Diagnostic Radiology, I recognize the clinical urgency that accompanies a suspected sarcoma diagnosis. A positive EWSR1 rearrangement serves as a decisive biomarker, yet it must always be interpreted within the full context of histopathology, imaging findings, and the patient’s overall clinical presentation. Our role is to ensure that every diagnostic step is supported by precise molecular evidence and compassionate guidance.”
— Mr. Prabhakar Reddy Kalathoor, Specialist Diagnostic Radiology (DHA Registration ID: 61713011)
Critical Medication Advisory
⚠️ Important Notice
Do not discontinue any prescribed medication without consulting your treating physician. Test results are intended to inform, not replace, professional medical advice.
Safety Exclusion Criteria & Emergency Red Flags
- Inadequate tissue sample – necrotic or extensively crushed tissue may yield inconclusive results
- Need for repeat biopsy if initial specimen is insufficient – never delay seeking medical attention
- Rapidly enlarging soft‑tissue/bone mass with severe unrelenting pain
- Pathological fracture or suspected spinal cord compression – emergency evaluation required
- Constitutional symptoms (unexplained fever, weight loss) alongside a suspicious mass – immediate clinical evaluation
- Pediatric patients (<18 years): Mandatory parental consent and specialist referral per Federal Decree‑Law No. 4 of 2016 on Medical Liability
If you experience any of the above red flags, proceed to the nearest emergency department or contact your oncologist immediately.
Patient FAQ & Clinical Guidance
1. What is the EWSR1 Gene Rearrangement Test Used For?
The EWSR1 gene rearrangement test detects specific chromosomal translocations essential for diagnosing Ewing sarcoma and related small round blue cell tumors. This FISH‑based assay helps distinguish Ewing sarcoma from other malignancies, guiding precision therapy and clinical trial eligibility.
2. How Should I Prepare for Tumor Tissue Sample Collection?
The sample is obtained via a biopsy performed by your oncologist; no fasting or medication changes are required before the procedure. A valid doctor’s prescription is mandatory. Prescription is not applicable for patients planning surgery, pregnancy cases, or those travelling abroad solely for testing purposes—please discuss with our team.
3. How Long Do Results Take and What Happens After I Receive Them?
Results are delivered within 7–8 working days, accompanied by a telephonic consultation with an oncology specialist to interpret the findings. Your report includes the specific EWSR1 rearrangement status, methodology details, and clinical correlation notes. Follow‑up with your treating physician is essential to integrate the result with your full care plan.
UAE Regulatory & Data Privacy Adherence
DNA Labs UAE strictly complies with Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All patient data, including genetic test results and clinical records, are processed, stored, and transmitted under robust encryption and access‑control protocols. Clinical safety and patient consent procedures adhere to Federal Decree‑Law No. 4 of 2016 on Medical Liability. Your privacy and data integrity remain our highest priority.
Clinical & Logistical Metadata
| Test Name | EWSR1 Gene Rearrangement (Ewing Sarcoma) Test |
| Price (AED) | 1,000 AED |
| Turnaround Time | 7–8 Working Days |
| Sample Type / Matrix | Formalin‑Fixed Paraffin‑Embedded (FFPE) Tumor Tissue |
| Methodology Used | Fluorescence In‑Situ Hybridization (FISH) – Break‑Apart Probe |
| ICD-10-CM Code | C41.9 |
| LOINC Code | 60515-0 |
| DHA Facility License & Laboratory Address | DHA License No: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | Corporate Lab: DNA Labs UAE |
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