Test Price
750 AEDโ Home Collection Available
๐ Results in 6โ7 Days (Sample Mon, Report Sat)
Chronic Lymphocytic Leukemia (CLL) Mutations Detection Panel 2 | 750 AED | DHA Licensed โ Dubai Healthcare City
Executive Summary & Core Metrics
The Chronic Lymphocytic Leukemia (CLL) Mutations Detection Panel 2 is a high-resolution genomic assay that detects key prognostic and predictive mutations (TP53, NOTCH1, SF3B1, and deletions such as 11q) using multiplex ligation-dependent probe amplification combined with PCR. This ISO 9001:2015 certified test delivers 99.9% diagnostic sensitivity, guiding targeted therapies and risk stratification. The test is performed at DNA Labs UAE, a DHA-licensed facility (License No. 1143) in Dubai Healthcare City. Mobile phlebotomy and temperature-controlled cold-chain home collection are available daily from 8 AM to 11 PM. Direct WhatsApp insurance verification is available at +971545488731.
Test Overview & Methodology
This panel employs MLPA-PCR (Multiplex Ligation-dependent Probe Amplification combined with PCR) to detect copy number variations and single nucleotide variants in key CLL genes. The methodology delivers 99.9% sensitivity for CNVs and SNVs, surpassing standard targeted NGS panels (typically ~95%). The turnaround time is 6โ7 days from sample collection to report (sample collected Monday, report Saturday).
| Feature | Our Test (DHA Certified) | Closest Alternative |
|---|---|---|
| Precision | 99.9% Diagnostic Sensitivity for CNVs and SNVs | ~95% (limited by NGS coverage gaps) |
| Methodology | MLPA-PCR (Multiplex Ligation-dependent Probe Amplification + PCR) | Targeted NGS Panel or Sanger Sequencing |
| Turnaround Time | 6โ7 Days (Sample Mon, Report Sat) | 10โ14 Days |
Physician Insight & Safety Protocols
"As a Consultant Medical Genetics with DHA registration 9294403, I emphasize that the CLL mutation panel is integral to risk-adapted treatment selectionโparticularly for assessing TP53 aberrations that predict poor response to chemoimmunotherapy. However, results must always be correlated with clinical findings and patient history; do not initiate or discontinue any therapy without consulting a qualified healthcare provider."
โ Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA: 9294403
Safety Advisory
โ ๏ธ Medication Warning
Do not discontinue prescribed medication without consulting your doctor. Altering your treatment plan based on genetic results alone may lead to disease progression or complications. All clinical testing is conducted under the provisions of Federal Decree-Law No. 4 of 2016 on Medical Liability, ensuring patient consent and safety.
Exclusion Criteria & Emergency Red Flags
- Active severe infection or sepsis (sample collection deferred until stabilization).
- Inability to provide at least 2 mL of whole blood in EDTA tube.
- Refusal or inability to sign the mandatory Genomics Clinical Information Requisition Form (Form 20).
- ER Red Flags: If you experience sudden worsening of lymph node swelling, unexplained fever >38.5ยฐC, or severe bleeding, seek urgent medical attention before testing.
Patient FAQ & Clinical Guidance
1. What specific mutations are detected by this CLL panel, and why are they important?
Our CLL Mutations Detection Panel 2 identifies critical gene mutations including TP53, NOTCH1, SF3B1, and 11q deletion, aiding personalized treatment planning. These biomarkers help oncologists predict disease aggressiveness and select targeted therapies such as venetoclax or BTK inhibitors, avoiding ineffective chemotherapy.
2. How do I prepare for the blood draw, and what is the sample handling requirement?
You must complete the mandatory Form 20, and the whole blood sample must be collected in a lavender-top EDTA tube, kept refrigerated, never frozen. Our home collection team will handle the cold-chain logistics; ensure the requisition form is fully filled with your clinical history. VIP Mobile Phlebotomy is available daily from 8 AM to 11 PM.
3. Are my genetic data and results kept confidential under UAE law?
Yes, all patient genetic data is protected under Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields, ensuring strict privacy and confidentiality. Our laboratory is ISO 9001:2015 certified and follows DHA data security protocols, with secure, encrypted storage and no unauthorized third-party access.
UAE Regulatory & Data Privacy Adherence
DNA Labs UAE operates under DHA Facility License No. 1143 and adheres strictly to UAE data protection laws. All patient data is processed in compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical testing and patient consent follow Federal Decree-Law No. 4 of 2016 on Medical Liability. Our laboratory is ISO 9001:2015 certified, ensuring quality management systems and secure handling of genomic data.
Clinical & Logistical Metadata
| Test Name | Chronic Lymphocytic Leukemia (CLL) Mutations Detection Panel 2 |
| Price (AED) | 750 AED |
| Turnaround Time | 6โ7 Days (Sample Mon, Report Sat) |
| Sample Type / Matrix | Peripheral Whole Blood (EDTA tube, lavender-top) |
| Methodology Used | MLPA-PCR (Multiplex Ligation-dependent Probe Amplification + PCR) |
| ICD-10-CM Code | C91.1 (Chronic lymphocytic leukemia of B-cell type) |
| LOINC Code | 88214-7 (Chronic lymphocytic leukemia panel - Blood by Molecular genetics method) |
| DHA Facility License & Laboratory Address | DNA Labs UAE, DHA License No. 1143, Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
ุฏุนู ุซูุงุฆู ุงููุบุฉ ู ุชุงุญ
ุงูุชุญูู ู ู ุงูุชุบุทูุฉ ุงูุชุฃู ูููุฉ
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
ุชููู ุนู ุงูุชุฎู ูู. ุฃุฑุณู ุตูุฑุฉ ู ู ุจุทุงูุฉ ุงูุชุฃู ูู ููุตูุฉ ุงูุทุจูุจ ุฅูู ูุฑูู ุงูุชุญูู ุงูู ุนุชู ุฏ ู ู ููุฆุฉ ุงูุตุญุฉ ุจุฏุจู ุนุจุฑ ุงููุงุชุณุงุจ. ุงุญุตู ุนูู ุชุญุฏูุซ ุงูุญุงูุฉ ูู ุฏูุงุฆู.
Available in Arabic, English, Hindi & Urdu
Preparation Required
["Complete the mandatory Genomics Clinical Information Requisition Form (Form 20).", "Ensure the whole blood sample is collected in a lavender-top EDTA tube."]
Medically Reviewed by Dr. Lina Osama Zaki Quteineh
All content reviewed by qualified professionals for accuracy.
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians