Test Price
2,800 AED✅ Home Collection Available
PRRT2 Gene (DYT10) Genetic Test in UAE | 2800 AED
Executive Summary & Core Metrics
A precise genetic test for detecting pathogenic variants in the PRRT2 gene causing paroxysmal kinesigenic dyskinesia and related neurological disorders, using ISO 15189 accredited next‑generation sequencing.
- Accuracy Guarantee: 99.9% diagnostic sensitivity via NGS with full gene coverage.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (available daily 8 AM – 11 PM).
- Clinical Guidance: Pre‑ and post‑test genetic counseling included.
- Insurance: Direct billing verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The PRRT2 NGS test sequences the entire coding region and splice sites of the PRRT2 gene to identify pathogenic or likely pathogenic variants. This high‐depth sequencing method provides >99.9% sensitivity for detecting single nucleotide variants, small insertions/deletions, and copy number variations in the PRRT2 locus. Results are interpreted by board‐certified clinical geneticists and confirmed by Sanger sequencing for clinically relevant findings.
| Feature | Our Test | Closest Alternative |
|---|---|---|
| Method | Next‑Generation Sequencing (NGS) | Single‑gene Sanger sequencing |
| Precision | >99.9% diagnostic accuracy for known and novel variants | Lower sensitivity for mosaic or intronic variants |
| Speed | 3–4 weeks | Often 6–8 weeks |
Physician Insight & Safety Protocols
“As a Consultant Medical Genetics specialist, I have witnessed how a precise genetic diagnosis can transform the management of movement disorders. The PRRT2 test empowers families with clarity, but it must be paired with careful clinical correlation and comprehensive genetic counseling. I strongly recommend that all patients undergo both pre‑test counseling to set expectations and post‑test counseling to understand results and implications for family members.”
Exclusion Criteria & Emergency Red Flags
- Active systemic infection or recent blood transfusion (within 2 weeks) may compromise DNA quality.
- Test not indicated for asymptomatic individuals without a family history of movement disorders or clinical suspicion.
- Seek immediate emergency care (call 998) if: sudden onset of severe muscle stiffness, loss of consciousness, prolonged seizures, or difficulty breathing. These symptoms require acute medical attention, not elective genetic testing.
Patient FAQ & Clinical Guidance
1. What sample types are accepted for the PRRT2 genetic test?
This test accepts whole blood (EDTA), extracted genomic DNA, or dried blood spot on FTA card. All methods yield high‑quality DNA for NGS analysis. For whole blood, a standard venipuncture sample is collected at our facility or via our VIP Mobile Phlebotomy service.
2. What is the turnaround time for results?
The PRRT2 NGS test turnaround time is three to four weeks from sample receipt to final report. This includes DNA extraction, library preparation, high‑depth sequencing, bioinformatics analysis, and dual‑specialist interpretation before release.
3. Is genetic counseling mandatory?
Yes, pre‑ and post‑test genetic counseling is mandatory for all patients undergoing PRRT2 testing. A certified genetic counsellor will draw a detailed pedigree, explain inheritance patterns, and discuss potential outcomes. After results, counseling ensures you fully understand the clinical significance and any recommended family screening.
4. Can I have this test if I have no symptoms?
This test is intended for individuals with clinical suspicion of paroxysmal kinesigenic dyskinesia or related disorders, or for those with a confirmed family history of a PRRT2 pathogenic variant. Asymptomatic individuals without such history should not undergo this test without prior genetic counseling.
UAE Regulatory & Data Privacy Adherence
DNA Labs UAE operates under DHA Facility License No. 1143 and strictly complies with:
- Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) – ensuring all genetic data is collected, processed, and stored with explicit patient consent and robust security measures.
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields – governing the secure electronic transmission and storage of medical records and test results.
- Federal Decree-Law No. 4 of 2016 on Medical Liability – ensuring that all clinical testing, patient consent, and reporting follow the highest standards of medical accountability.
Your genetic information is anonymised and encrypted; results are shared only with you and your designated healthcare provider.
Clinical & Logistical Metadata
| Test Name | PRRT2 Gene (DYT10) Genetic Test (NGS Full Gene Sequencing) |
| Price (AED) | 2,800 AED (includes genetic counseling) |
| Turnaround Time | 21–28 days (3–4 weeks) |
| Sample Type / Matrix | Whole blood (EDTA), extracted DNA, or dried blood spot (FTA card) |
| Methodology Used | Next-Generation Sequencing (NGS) with full gene coverage, validated by Sanger confirmation |
| ICD-10-CM Code | G24.8, G25.8 |
| LOINC Code | 81304-8 |
| DHA Facility License & Laboratory Address | License No. 1143 – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE. Corporate Lab: DNA Labs UAE |
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All reports reviewed by DHA-Certified physicians