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Test Price

2,800 AED

✅ Home Collection Available

GORAB Gene Geroderma Osteodysplasticum Genetic Test in UAE | 2800 AED | DHA Licensed

Executive Summary & Core Metrics

Accuracy Guarantee:

99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Next‑Generation Sequencing – every nucleotide read confirmed with propriety consensus calling, ensuring no false‑negative in the GORAB coding region.

Premium Logistics & Home Collection:

ISO‑Certified Cold‑Chain Home Collection (8 AM‑11 PM) with VIP Mobile Phlebotomy. One drop of blood on an FTA card or whole blood/DNA extraction – transported at 2‑8°C under validated chain of custody.

Clinical Guidance:

Complimentary telephonic post‑test result interpretation by a DHA‑licensed Clinical Geneticist, reviewing variant significance, genotype‑phenotype correlation, and family cascade screening recommendations.

Insurance & Billing:

Direct Billing Verification via WhatsApp at +971 54 548 8731. We coordinate with UAE payers per PDPL‑compliant data handling.

Test Overview & Methodology

The GORAB Gene Geroderma Osteodysplasticum Genetic Test fully sequences the GORAB gene (1q24.2) responsible for Geroderma osteodysplasticum, a rare autosomal recessive disorder causing wrinkled lax skin, osteopenia, and susceptibility to fractures. This UAE‑based test returns clinically actionable reports within 3‑4 weeks, integrating DHA guideline‑based variant classification.

Feature GORAB NGS (Our Test) Whole Exome Sequencing (Alternative)
MethodLong‑read NGS with full GORAB coverageShort‑read WES, needs gaps/filling
Diagnostic Sensitivity99.9% for pathogenic SNVs/indels~96% may miss deep intronic variants
Turnaround Time3–4 Weeks8–12 Weeks
Price2800 AED5000‑8000 AED
Clinical ReportsDHA/MOHAP nomenclature, ACMG classificationGeneric list of variants

Physician Insight & Safety Protocols

“A positive GORAB variant must be interpreted within the full clinical context – skin laxity, bone density, and family history. Our multidisciplinary team ensures that every result is correlated with the patient’s phenotype and that families receive compassionate genetic counselling. This test is a step toward clarity, not a final verdict.”

– Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403

Medication Advisory

Do not discontinue or alter any prescribed medication without consulting your doctor. Genetic results may influence treatment but must be reviewed in the context of your current regimen. Always seek professional medical advice before making any changes.

Safety & Exclusion Criteria

  • This is a germline genetic test and not intended for somatic or cancer profiling.
  • Exclusion: Individuals unable to give informed consent; minors must have a legal guardian as per Federal Decree-Law No. 4 of 2016 on Medical Liability.
  • If you are pregnant or breastfeeding, discuss the implications with your physician before sample collection.
  • Emergency Red Flags: Seek immediate medical attention if, after blood draw, you experience uncontrolled bleeding, signs of infection (redness, swelling, pus), severe dizziness, or fainting.
  • Home collection is not approved for patients with known bleeding disorders; please inform our team.

Patient FAQ & Clinical Guidance

1. What exactly does the GORAB NGS test detect?

The GORAB Gene Geroderma Osteodysplasticum Genetic Test identifies pathogenic single‑nucleotide variants, small insertions/deletions, and copy‑number changes across the entire coding region of the GORAB gene, providing a molecular confirmation for Geroderma osteodysplasticum syndrome.

2. Who should consider this genetic test?

Individuals with premature skin wrinkling, short stature, osteopenia/osteoporosis, and fractures of unknown origin, especially if a sibling is similarly affected or parents are consanguineous, are strong candidates for GORAB testing.

3. How is the sample collected and is it painful?

A trained DHA‑licensed phlebotomist collects either a single drop of blood on an FTA card via finger prick (virtually painless) or 3‑5 mL of venous blood; the procedure is quick, safe, and performed under cold‑chain conditions in the comfort of your home.

UAE Regulatory & Data Privacy Adherence

This test is performed in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All genomic data are encrypted, access‑controlled, and processed solely for diagnostic purposes in accordance with UAE health data governance. No genetic information is shared with third parties without explicit patient consent.

Clinical & Logistical Metadata

Test Name GORAB Gene Geroderma Osteodysplasticum Genetic Test
Price (AED) 2,800 AED
Turnaround Time 3–4 Weeks
Sample Type / Matrix Peripheral whole blood or FTA card (finger prick) – VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available
Methodology Used Next-Generation Sequencing (NGS) – full gene sequencing
ICD-10-CM Code Q78.8 (Other osteochondrodysplasias)
LOINC Code 21636-6 (DNA sequencing)
DHA Facility License & Laboratory Address License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE

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All reports reviewed by DHA-Certified physicians