Test Price
2,800 AED✅ Home Collection Available
ITGA3 Gene NGS Test – Interstitial Lung Disease, Nephrotic Syndrome & Epidermolysis Bullosa Congenita
Executive Summary & Core Metrics
Trust Guarantees
- 99.9% Diagnostic Sensitivity – ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139).
- Premium Logistics – VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
- Clinical Guidance – Telephonic Post-Test Clinical Guidance for result interpretation with DHA-licensed genetics professionals.
- Insurance Support – Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
This NGS test sequences the entire coding region of the ITGA3 gene associated with a rare multi-system disorder comprising interstitial lung disease, nephrotic syndrome, and epidermolysis bullosa congenita. Our ISO-certified laboratory delivers clinical-grade results within 3–4 weeks using advanced NGS technology, providing comprehensive variant detection beyond single-gene Sanger approaches.
| Feature | Our ITGA3 NGS Test | Closest Alternative (Sanger Sequencing) |
|---|---|---|
| Precision & Coverage | Full gene sequencing, >99% sensitivity, detects all variants | Targets only known mutations; limited variant discovery |
| Methodology | Next Generation Sequencing (NGS) + bioinformatics | Sanger sequencing (single amplicons) |
| Sample Types | Whole blood (EDTA), extracted DNA, Dried Blood Spot (FTA card) | Whole blood (EDTA) only, requires high DNA yield |
| Turnaround Time | 3–4 Weeks | 4–6 Weeks |
| Clinical Utility | Comprehensive diagnosis & family screening | May miss novel mutations, lower diagnostic yield |
| Price (AED) | 2800 | ~2000 (limited insight) |
Physician Insight & Safety Protocols
"As a consultant medical geneticist, I understand the significance of the ITGA3 gene analysis in diagnosing this rare, complex syndrome. However, results must always be correlated with clinical symptoms, pedigree information, and other lab findings. Please discuss all findings with your treating physician before making any health decisions."
— Lina Osama Zaki Quteineh, Consultant Medical Genetics (DHA Registration ID: 9294403)
Advisory Notice
Do not discontinue any prescribed medication without consulting your physician. Genetic test results should be interpreted in the context of clinical findings and family history. A genetic counseling session is recommended before and after testing.
Exclusion Criteria & Emergency Red Flags
Contraindications / Exclusion:
- Allogeneic hematopoietic stem cell transplant within the last 6 months (risk of chimeric results).
- Pregnancy (first trimester) unless clinically urgent and discussed with a genetics specialist.
- Inability to provide informed consent without a legally authorized guardian per UAE law.
Seek Emergency Care if You Experience:
- Sudden severe respiratory distress or hemoptysis.
- Rapid onset of generalized edema, anuria, or acute kidney injury symptoms.
- Widespread blistering with fever, chills, or signs of systemic infection.
Patient FAQ & Clinical Guidance
1. What is the ITGA3 Gene NGS Test?
This test sequences the ITGA3 gene to diagnose the rare congenital disorder affecting lungs, kidneys, and skin. It identifies pathogenic variants causing the syndrome that combines interstitial lung disease, nephrotic syndrome, and epidermolysis bullosa. The test is performed on blood, extracted DNA, or dried blood spot, providing a definitive molecular diagnosis to guide management and family planning.
2. How is the sample collected?
A licensed phlebotomist collects a blood or DNA sample via home visit, ensuring safe cold-chain transport. We offer VIP mobile phlebotomy across the UAE from 8 AM to 11 PM, using hospital-grade cold-chain logistics. Alternatively, you can submit a dried blood spot on an FTA card or previously extracted DNA. A genetic counselling session (video/phone) is conducted beforehand to draw a pedigree and explain the procedure.
3. How long do results take?
Results typically take 3 to 4 weeks from sample arrival at our ISO-certified molecular lab. This timeframe includes DNA extraction, NGS library preparation, sequencing, bioinformatics analysis, and clinical interpretation by DHA-licensed geneticists. A telephonic consultation will be scheduled to explain your report in detail.
UAE Regulatory & Data Privacy Adherence
This testing process is fully compliant with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All genetic data is handled with strict confidentiality under these regulations. Informed consent is obtained in accordance with Federal Decree-Law No. 4 of 2016 on Medical Liability.
Clinical & Logistical Metadata
| Test Name | ITGA3 Gene NGS Test |
| Price (AED) | 2800 |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Whole Blood (EDTA), Extracted DNA, Dried Blood Spot (FTA card) |
| Methodology Used | Next Generation Sequencing (NGS) with bioinformatics analysis |
| ICD-10-CM Code | Q81.9 |
| LOINC Code | 88537-7 |
| DHA Facility License & Laboratory Address | License No: 1143, Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE – DNA Labs UAE |
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Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians