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Test Price

2,800 AED

✅ Home Collection Available

SPG7 Gene Sequencing (NGS) – Hereditary Spastic Paraplegia Type 7

Executive Summary & Core Metrics

Executive Summary

Our SPG7 Genetic Test delivers 99.9% diagnostic sensitivity for Hereditary Spastic Paraplegia type 7, processed at an ISO 9001:2015‑certified, DHA‑regulated laboratory. Benefit from VIP mobile phlebotomy and temperature‑controlled cold‑chain home collection, telephonic post‑test clinical guidance with a consultant medical geneticist, and instant insurance billing verification through WhatsApp. All handling adheres strictly to Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields.


Price: 2,800 AED  ·  Turnaround Time: 3–4 weeks  ·  Sample Type: Whole blood (EDTA)  ·  Methodology: Next‑Generation Sequencing (NGS, coverage >100×)

Test Overview & Methodology

The SPG7 Genetic Test uses next‑generation sequencing to analyze the entire coding region of the SPG7 gene, detecting pathogenic variants linked to Hereditary Spastic Paraplegia type 7 and other progressive spastic‑ataxic disorders. Results support definitive diagnosis, genetic counselling, and personalized neurological surveillance, making it an essential tool for neurogenetics clinics across the UAE.

Feature Our SPG7 NGS Test Closest Alternative (Sanger Panel)
Methodology NGS deep sequencing (coverage >100×) Sanger sequencing of selected exons only
Variant Detection Single‑nucleotide variants, small indels, copy‑number changes Point mutations and small indels; no CNV analysis
Turnaround Time 3–4 Weeks 6–8 Weeks
Diagnostic Sensitivity 99.9% ~90–95% (misses deep intronic/regulatory variants)
Price 2,800 AED 3,500+ AED (often requires additional reflex tests)

Physician Insight & Safety Protocols

“Genetic testing for SPG7 is a powerful diagnostic tool, but results should be interpreted in conjunction with a thorough clinical evaluation and family history. A pathogenic variant confirms the diagnosis of hereditary spastic paraplegia type 7, yet it does not predict the age of onset or severity. I urge all patients to schedule a post‑test consultation with a qualified medical geneticist to understand the implications for themselves and their relatives.” — Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403

Advisory – Medication Continuity

Do not discontinue any prescribed medication without consulting your treating physician.

Exclusion Criteria (Patient Safety)

  • Active systemic infection or febrile illness (risk of sample degradation)
  • Inability to provide the minimum blood volume (2 mL whole blood in EDTA)
  • Minors without explicit guardian consent (in line with UAE Federal Law No. 2 of 2019)
  • Recent blood transfusion (<4 weeks) or allogeneic bone marrow transplant (may interfere with germline DNA analysis)

Emergency Red Flags – Seek Immediate Medical Attention

  • Sudden‑onset severe leg weakness or inability to walk
  • New seizures, confusion, or loss of consciousness
  • Acute visual loss, speech arrest, or facial drop

Patient FAQ & Clinical Guidance

1. What is the SPG7 Genetic Test and why should I consider it?

The SPG7 Genetic Test sequences the entire SPG7 gene to identify hereditary mutations responsible for progressive spastic paraplegia, enabling early therapeutic planning, family risk assessment, and lifestyle adjustments.

2. How is the sample collected and when will I receive my results?

A certified mobile phlebotomist performs a home blood draw using an ISO‑certified cold‑chain kit, with results securely reported online within 3–4 weeks. VIP Mobile Phlebotomy & Temperature‑Controlled Cold‑Chain Home Collection is available daily from 8 AM to 11 PM.

3. Does insurance cover the SPG7 test and how can I verify?

Most UAE insurers provide partial or full reimbursement when the test is medically indicated; our team instantly confirms eligibility and submits the claim via WhatsApp at +971 54 548 8731.

UAE Regulatory & Data Privacy Adherence

Regulatory Compliance & Insurance

Our laboratory is licensed under DHA (License No. 1143) and holds ISO 9001:2015 certification. We operate in full alignment with Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Direct insurance billing verification and claim initiation are available via WhatsApp at +971 54 548 8731.

Clinical & Logistical Metadata

Test Name SPG7 Gene Sequencing (NGS)
Price (AED) 2,800
Turnaround Time 3–4 Weeks
Sample Type / Matrix Whole blood (EDTA) – VIP Mobile Phlebotomy & Cold‑Chain Home Collection Available
Methodology Used Next‑Generation Sequencing (NGS, coverage >100x)
ICD-10-CM Code G11.4
LOINC Code 55233-1
DHA Facility License & Laboratory Address License No. 1143 – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE – DNA Labs UAE

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