Test Price
1,000 AED✅ Home Collection Available
DRPLA (Dentatorubral-Pallidoluysian Atrophy) Gene Analysis in UAE | 1000 AED | 2026 DHA Guidelines
تحليل جين DRPLA (الضمور السني الحمراوي اللويزي الشاحب) في الإمارات | 1000 درهم | معتمد من هيئة الصحة بدبي
الملخص التنفيذي
دقة تشخيصية بنسبة 99.9% باستخدام تحليل القطع الجزيئية المعتمد بتقنية ISO 9001. خدمة سحب عينات منزلية متميزة بواسطة فريق تمريض متنقل وتوصيل بارد معتمد. استشارة طبية هاتفية بعد الفحص لتوجيهك حول النتائج. التحقق المباشر من التغطية التأمينية عبر واتساب على الرقم +971 54 548 8731.
Test Overview
The DRPLA gene analysis is a definitive molecular test that detects pathogenic CAG trinucleotide repeat expansions in the ATN1 gene, confirming a diagnosis of dentatorubral-pallidoluysian atrophy—a progressive neurodegenerative disorder. This test enables precise clinical classification and family risk assessment.
اختبار جيني يكشف توسع تكرار CAG في جين ATN1 المسؤول عن الضمور السني الحمراوي اللويزي الشاحب، مما يوفر تشخيصاً دقيقاً وتقييماً للمخاطر الوراثية العائلية.
| Feature | Our DRPLA Gene Test | Closest Alternative (Whole Exome Sequencing) |
|---|---|---|
| Methodology | PCR‑based Fragment Analysis & STR Genotyping (Capillary Electrophoresis) – gold standard for repeat expansions | Short‑read sequencing; often misses repeat‑length variants |
| Diagnostic Sensitivity | 99.9% for ATN1 expanded alleles | ~80–90% in repeat regions |
| Turnaround Time | 5 working days (Mon–Fri) | 4–6 weeks |
| Cost | 1000 AED | Often >5000 AED |
Physician Insight & Safety Protocol
“As a neurologist practising in the UAE for over 15 years, I have seen how a precise genetic diagnosis transforms care for families affected by DRPLA. This test offers clarity, but I must stress that the result must always be correlated with your clinical picture and discussed with your specialist before any action. A positive result is not a verdict; it is the beginning of a personalised management plan.”
— Dr. Prabhakar Reddy, DHA License 61713011, Consultant Neurologist
Medication Warning
Do not discontinue prescribed medication without consulting your doctor. This test does not replace ongoing neurological follow‑up.
Exclusion Criteria & Emergency Red Flags
- Test not offered to asymptomatic minors without written parental / legal guardian consent and pre‑test genetic counselling, as per UAE Federal Law No. 3 of 2016 (Wadeema’s Law) and 2026 amendments.
- Prenatal diagnosis is only performed after multidisciplinary genetic counselling and informed consent.
- Results must not be used as the sole basis for major clinical decisions without specialist interpretation.
- Seek emergency care immediately if you experience: sudden onset of severe involuntary movements, uncontrollable seizures, loss of consciousness, or suicidal ideation after receiving test results.
Patient FAQ & Clinical Guidance
1. What is DRPLA gene analysis and why is it needed?
DRPLA gene analysis detects abnormal CAG repeats in the ATN1 gene causing a rare progressive brain disorder, aiding accurate diagnosis and family planning. The test is recommended for individuals with progressive ataxia, chorea, myoclonus, or dementia, especially if there is a family history. It can differentiate DRPLA from other hereditary ataxias and inform reproductive options.
يكشف تحليل جين DRPLA عن توسع متكررات CAG غير الطبيعية في جين ATN1 المسبب لاضطراب دماغي نادر، مما يساعد في التشخيص الدقيق وتنظيم الأسرة.
2. How should I prepare for the?
No fasting or special preparation is required; simply provide a 4 mL blood sample in a lavender‑top EDTA tube and complete Form 20. Avoid freezing the sample. Our home collection team will ensure cold‑chain transport. You must also fill out the mandatory Genomics Clinical Information Requisition Form (Form 20) with your clinical details.
لا يلزم الصيام أو أي تحضير خاص؛ فقط قم بتقديم عينة دم بحجم 4 مل في أنبوب EDTA ذو الغطاء الخزامي واستكمال النموذج 20. تجنب تجميد العينة.
3. How quickly will I receive my results and what support is available?
You will receive your results within 5 working days, and complimentary telephonic guidance from a clinical expert helps interpret them. The report includes the exact number of CAG repeats and the interpretation in a clear medical summary. If needed, a follow‑up appointment with one of our collaborating neurologists or genetic counsellors can be arranged.
ستتلقى نتائجك خلال 5 أيام عمل، وستتاح لك استشارة هاتفية مجانية مع خبير سريري لتفسير النتائج.
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توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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