Test Price
2,800 AED✅ Home Collection Available
PANK2 Gene Pantothenate Kinase-Associated Neurodegeneration Genetic Test in UAE | 2,800 AED | DNA Labs UAE
Executive Summary & Core Metrics
Your precision‑guided pathway to clarity on neurodegeneration with iron accumulation.
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing (ISO 9001:2015).
- Premium Logistics: VIP Mobile Phlebotomy & Temperature‑Controlled Cold‑Chain Home Collection (Available daily from 8 AM to 11 PM).
- Clinical Guidance: Telephonic Post‑Test Clinical Guidance in Result Interpretation by DHA‑licensed genetics specialists.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
This advanced DNA test screens the entire PANK2 gene using Next‑Generation Sequencing (NGS) technology, identifying pathogenic variants responsible for Pantothenate Kinase‑Associated Neurodegeneration (PKAN). Early molecular diagnosis allows for precise clinical management and genetic counselling tailored to UAE families.
| Feature | Our Test (NGS Full Gene) | Closest Alternative (Targeted Mutation Panel) |
|---|---|---|
| Precision / Method | NGS – covers all exons, intron‑exon boundaries, and promoter | PCR / Sanger sequencing for common PANK2 variants only |
| Sensitivity | >99.9% for single nucleotide variants, indels, CNVs | ~85% (misses private, rare, or deep intronic mutations) |
| Turnaround Time | 3–4 Weeks | 2–3 Weeks |
| Clinical Utility | Gold standard for diagnostic confirmation & carrier screening in families | Suitable only when family mutation is known; may yield false negatives |
Physician Insight & Safety Protocols
“A molecular diagnosis of PKAN through comprehensive PANK2 gene sequencing provides families with definitive answers where clinical uncertainty previously prevailed. Genetic counselling before and after testing is essential to discuss inheritance patterns, reproductive options, and the variable expressivity of this condition. In my practice, I emphasise that a positive result must always be correlated with neurological imaging and clinical examination to guide prognosis and multidisciplinary care.”
Lina Osama Zaki Quteineh, Consultant Medical Genetics – DHA Registration ID: 9294403
Clinical Advisory: Medication Continuation Notice
⚠️ Maintain all prescribed therapies for movement disorders, seizures, or spasticity unless explicitly instructed otherwise by your neurologist. Genetic findings complement, not replace, ongoing clinical management.
Exclusion Criteria & Emergency Indicators
Exclusion Criteria
- Acute febrile illness or uncontrolled systemic infection at the time of sampling.
- Inability to provide informed consent (or legal guardian consent) for genetic testing.
- Recent blood transfusion (<2 weeks) that may interfere with germline DNA analysis on whole blood.
Emergency Red Flags (Seek Immediate Care)
- Sudden severe dystonia, opisthotonos, or uncontrolled muscle spasms.
- Acute vision loss or rapid deterioration in gait.
- Difficulty breathing, choking, or aspiration pneumonia.
- Signs of acute encephalopathy or status epilepticus.
Patient FAQ & Clinical Guidance
1. What does a positive PANK2 NGS result mean for my child’s future?
A positive result confirms a pathogenic variant in both PANK2 alleles, leading to pantothenate kinase‑associated neurodegeneration (PKAN) with variable progression that must be interpreted alongside neurological imaging. Genetic counselling will provide a detailed discussion of prognosis, available therapies, and family planning options.
2. How is the sample collected and can I arrange a home visit in Dubai?
We offer VIP Mobile Phlebotomy with temperature‑controlled cold‑chain logistics available daily from 8 AM to 11 PM. A certified phlebotomist draws a small peripheral whole blood sample (EDTA tube) or collects a finger‑prick on an FTA card, with strict cold‑chain transport to our ISO‑accredited laboratory.
3. Why is genetic counselling required before testing?
Genetic counselling ensures you understand the implications of testing, constructs a detailed pedigree, and obtains informed consent, aligning with UAE regulations (Federal Decree‑Law No. 4 of 2016 on Medical Liability) and international ethical guidelines for neurogenetic disorders.
4. How long does it take to receive results and how are they delivered?
The standard turnaround time is 3–4 weeks from sample receipt. Results are delivered via secure electronic PDF with a detailed clinical interpretation report, and a telephonic consultation with our genetics team is scheduled to explain the findings and next steps.
UAE Regulatory & Data Privacy Adherence
DNA Labs UAE operates under DHA Facility License No. 1143 and fully complies with Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) for the processing of genetic data, as well as Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All genetic testing procedures adhere to the safety and consent requirements of Federal Decree‑Law No. 4 of 2016 on Medical Liability. Patient data is encrypted, access‑controlled, and never shared without explicit written consent.
Clinical & Logistical Metadata
| Test Name | PANK2 Gene Pantothenate Kinase‑Associated Neurodegeneration Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Whole Blood (EDTA) or FTA Card (Finger‑Prick) |
| Methodology Used | Next‑Generation Sequencing (NGS) – Full Gene Coverage |
| ICD‑10‑CM Code | G23.0 |
| LOINC Code | 94233-2 |
| DHA Facility License & Laboratory Address | DHA Facility License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE – DNA Labs UAE |
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All reports reviewed by DHA-Certified physicians