Test Price
2,800 AED✅ Home Collection Available
MAPT Gene Testing for Frontotemporal Dementia (NGS) in UAE | 2800 AED
Executive Summary & Core Metrics
Precision Genetic Screening: A high‑resolution NGS‑based analysis of the MAPT gene coding region for pathogenic mutations causing frontotemporal lobar degeneration (FTLD‑tau subtype). Recommended by neurologists and geneticists across the UAE for inherited dementia risk stratification.
- Analytical Accuracy: 99.9% sensitivity for coding variants and known copy‑number changes.
- Premium Service: VIP mobile phlebotomy & temperature‑controlled cold‑chain home collection (daily 8 AM – 11 PM).
- Clinical Support: Post‑result genetic counselling by phone to interpret risk and guide next steps.
- Insurance Verification: Direct policy check via WhatsApp at +971 54 548 8731.
Test Overview & Methodology
An NGS‑based genetic test that analyzes the entire coding region of the MAPT gene for pathogenic mutations causing frontotemporal lobar degeneration (FTLD‑tau subtype). Recommended by neurologists, geneticists and anti‑aging specialists in the UAE to clarify inherited risk, guide clinical surveillance and inform family planning.
| Feature | Our MAPT NGS Test | Standard Sanger Sequencing |
|---|---|---|
| Technology | Next Generation Sequencing (NGS) – full gene coverage including deep intronic regions | Sanger sequencing of select exons only |
| Diagnostic Sensitivity | 99.9% for coding variants & known copy number changes | ~95% for targeted point mutations; misses large deletions |
| Turnaround Time | 3 – 4 Weeks | 4 – 6 Weeks |
| Clinical Utility | Simultaneous detection of missense, nonsense, splice-site variants and exon-level CNVs | Limited to previously known hotspots |
Physician Insight & Safety Protocols
“Genetic testing for dementia is a deeply personal journey. I remind patients that this test clarifies hereditary risk but must always be interpreted alongside a comprehensive neurological exam and family history. A positive result is not a verdict – it opens the door to proactive monitoring, clinical trials engagement, and essential family counseling.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Clinical Advisory & Safety Guidance
⚠ Important Clinical Advisory
Do not discontinue any prescribed medication, including acetylcholinesterase inhibitors or anticoagulants, without direct consultation with your treating physician. Abrupt cessation may precipitate rapid cognitive decline or thrombotic events. Always consult your neurologist before making any changes to your treatment regimen.
Patient Exclusion Criteria & Emergency Red Flags
🚨 Exclusion Criteria & Safety Alerts
- Exclusion: Inability to provide informed consent (applicable to minors without guardian authorization per UAE personal data protection regulations).
- Exclusion: Blood transfusion within the last 14 days – may compromise DNA integrity and lead to false‑negative results.
- Exclusion: Acute psychiatric instability where result disclosure could precipitate harm without immediate psychological support.
- Emergency Red Flags: If you experience suicidal thoughts, severe anxiety, or uncontrolled distress after receiving results, call UAE Emergency 998 or visit the nearest ER.
Patient FAQ & Clinical Guidance
1. Why do I need the MAPT gene test if brain imaging is normal?
This test detects pathogenic MAPT variants years before structural changes appear on MRI, enabling early risk stratification and family planning. The genetic insight allows physicians to initiate monitoring protocols and lifestyle interventions well before clinical symptoms become apparent.
2. How reliable is the NGS method for this gene?
With 99.9% analytical sensitivity, NGS comprehensively reads all coding exons, intron‑exon boundaries, and detects large deletions or duplications that Sanger methods miss. This ensures that even rare or novel pathogenic variants are captured with high confidence.
3. Will my insurance cover the MAPT genetic test in Dubai?
Many UAE insurers cover medically‑necessary neurogenetic panels when supported by a neurologist’s referral. Send your policy details via WhatsApp to +971 54 548 8731 for immediate verification and a clear breakdown of coverage limits.
UAE Regulatory & Data Privacy Adherence
🇦🇪 UAE Data Privacy & Health Regulation
All testing and patient data handling strictly comply with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and patient consent are governed by Federal Decree-Law No. 4 of 2016 on Medical Liability.
🔬 Accreditation & Quality Standards
ISO 9001:2015 Certified (Cert: INT/EGQ/2509DA/3139). The laboratory follows CLSI and CAP guidelines for molecular genetic testing, ensuring consistent quality and internationally benchmarked results.
📋 Specimen Handling & Logistics
Accepts: Whole Blood, Extracted DNA, or Dried Blood Spot on FTA Card. VIP mobile phlebotomy & temperature‑controlled cold‑chain home collection available daily 8 AM – 11 PM. Turnaround time is 3–4 weeks from sample receipt.
Clinical & Logistical Metadata
| Test Name | MAPT Gene Sequencing for Frontotemporal Dementia (NGS) |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3 – 4 Weeks |
| Sample Type / Matrix | Whole Blood (EDTA), Extracted DNA, or Dried Blood Spot on FTA Card; VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM) |
| Methodology Used | Next Generation Sequencing (NGS) – full coding region coverage with deep intronic boundary analysis |
| ICD-10-CM Code | G31.09 |
| LOINC Code | 92821-5 |
| DHA Facility License & Laboratory Address | DHA Facility License Number: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | Corporate Lab Branding: DNA Labs UAE |
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ISMS 27001:2022
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All reports reviewed by DHA-Certified physicians