Test Price
2,800 AED✅ Home Collection Available
HSPB1 Gene Neuronopathy Distal Hereditary Motor Neuropathy Type 2B Genetic Test in UAE | 2,800 AED
Executive Summary & Core Metrics
Clinical Executive Summary
High‑precision genetic test for diagnosing distal hereditary motor neuropathy type 2B linked to HSPB1 gene mutations, using Next‑Generation Sequencing with genetic counselling, DHA‑licensed home collection, and post‑result clinical guidance.
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139).
- Premium Logistics: VIP Mobile Phlebotomy & Temperature‑Controlled Cold‑Chain Home Collection (Available daily from 8 AM to 11 PM).
- Clinical Guidance: Telephonic Post‑Test Clinical Guidance interpreting results with DHA‑licensed specialists.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
This HSPB1 Gene Neuronopathy Distal Hereditary Motor Neuropathy Type 2B Genetic Test precisely identifies pathogenic variants in the HSPB1 gene using Next‑Generation Sequencing, enabling definitive diagnosis of distal hereditary motor neuropathy type 2B and guiding targeted neurological care. The test covers all coding exons and flanking splice sites, delivering a clinically actionable report within 3–4 weeks, fully aligned with DHA genetic testing regulations.
| Feature | Our NGS Test (HSPB1 Focus) | Closest Alternative (Sanger Sequencing / Limited Panel) |
|---|---|---|
| Technology | NGS (Next‑Generation Sequencing) with 200× average depth | Sanger sequencing or non‑specialized gene panel |
| Variant Detection | Single nucleotide variants, small indels, and copy number variations (CNV) | Point mutations only; CNVs often missed |
| Coverage | Complete coding region + 10 bp flanking intronic regions | Selected exons or hotspot regions |
| Turnaround Time | 3–4 Weeks | 4–6 Weeks |
| Diagnostic Sensitivity | >99.9% | ~85–90% for selected mutations |
| Clinical Report | ACMG‑classified variants + genetic counselling session | Often limited interpretation |
Physician Insight & Safety Protocols
“As a consultant medical geneticist, I confirm that a positive HSPB1 result provides strong confirmation of a hereditary motor neuropathy, but must be correlated with a detailed neuromuscular examination and family history. This test does not substitute for a comprehensive neurological assessment, and we remain available for post‑test counselling to interpret findings in your clinical context.” – Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403.
Important Clinical Advisory
Do not discontinue prescribed medication or modify your treatment plan without consulting your treating physician. A genetic diagnosis informs but does not replace ongoing medical supervision.
Exclusion Criteria & Emergency Red Flags
- Exclusion Criteria: Not indicated for acute neuropathy symptoms requiring emergency admission; individuals unable to provide informed consent (unless legal guardian present); testing of minors strictly in accordance with Federal Decree‑Law No. 4 of 2016 on Medical Liability and only after genetic counselling.
- Emergency Red Flags – seek immediate medical attention: Sudden respiratory difficulty or diaphragmatic weakness; rapid progression of limb weakness over days; loss of independent ambulation; unexplained falls with head injury; signs of autonomic crisis (tachycardia, labile blood pressure).
Patient FAQ & Clinical Guidance
1. How accurate is the HSPB1 NGS test for diagnosing distal hereditary motor neuropathy type 2B?
Our NGS‑based assay achieves >99.9% diagnostic sensitivity for pathogenic and likely pathogenic HSPB1 variants, covering the entire coding region. The methodology adheres to ACMG guidelines and uses ISO‑accredited laboratory procedures under DHA license, ensuring clinically reliable results for neurologists and geneticists across the UAE.
2. What sample types are accepted and how does the home collection service work in Dubai and Abu Dhabi?
We accept whole blood, extracted DNA, or a single drop of blood on an FTA card, with samples collected at your doorstep by DHA‑licensed phlebotomists. The cold‑chain logistics vehicle arrives at your scheduled time (8 AM to 11 PM), completes the collection within minutes, and transports the specimen to our ISO‑certified molecular genetics laboratory, eliminating the need for hospital visits.
3. Is this genetic test covered by UAE insurance and must I be a UAE resident?
Many leading UAE insurers cover the HSPB1 NGS test when ordered by a neurologist or clinical geneticist with a documented medical necessity. Our team performs direct billing verification via WhatsApp, confirming your policy coverage before sample collection. The service is available to all UAE residents and citizens; visitors may access the test with a referral from a DHA‑registered physician.
UAE Regulatory & Data Privacy Adherence
All personal data and genetic information are processed in compliance with Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Patient consent is obtained in accordance with Federal Decree‑Law No. 4 of 2016 on Medical Liability. Results are encrypted, stored securely, and only shared with the ordering physician and the patient. The laboratory operates under DHA Facility License No. 1143 and adheres to international standards for genetic data confidentiality.
Clinical & Logistical Metadata
| Test Name | HSPB1 Gene Neuronopathy Distal Hereditary Motor Neuropathy Type 2B Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Whole Blood, Extracted DNA, or FTA Card (Peripheral Blood) – VIP Mobile Phlebotomy & Temperature‑Controlled Cold‑Chain Home Collection (Available daily from 8 AM to 11 PM) |
| Methodology Used | Next‑Generation Sequencing (NGS) – Complete coding region + flanking splice sites, 200× average depth, ACMG variant classification |
| ICD-10-CM Code | G60.8 (Other hereditary and idiopathic neuropathies) |
| LOINC Code | 82325-7 (HSPB1 gene targeted mutation analysis) |
| DHA Facility License & Laboratory Address | DHA Facility License Number: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | Corporate Lab Branding: DNA Labs UAE |
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All reports reviewed by DHA-Certified physicians