Test Price
2,800 AED✅ Home Collection Available
DNAJC3 Gene-Related Combined Cerebellar and Peripheral Ataxia with Hearing Loss and Diabetes Mellitus – Genetic Test in UAE | 2800 AED | DHA Compliant
Executive Summary & Core Metrics
Executive Summary
This ISO-certified genetic test detects pathogenic variants in the DNAJC3 gene with 99.9% diagnostic sensitivity, enabling definitive diagnosis of ataxia, hearing loss, and diabetes mellitus. We offer VIP mobile phlebotomy with temperature-controlled cold-chain home collection, direct insurance billing, and post-test clinical guidance by DHA-licensed physicians.
Test Overview & Methodology
This advanced genetic test screens the entire coding region of the DNAJC3 gene to identify pathogenic variants linked to the rare neuroendocrine syndrome of cerebellar ataxia, peripheral neuropathy, sensorineural hearing loss, and early-onset diabetes. Our ISO-certified, DHA-compliant laboratory delivers results within 3–4 weeks, empowering precise clinical management and family planning.
| Parameter | Our NGS Test | Alternative (Whole Exome Sequencing) |
|---|---|---|
| Technology | Targeted NGS + Sanger Confirmation | Whole Exome Sequencing (WES) |
| DNAJC3 Coverage | 100% coding region & splice sites | Variable, may miss deep intronic variants |
| Diagnostic Sensitivity | >99.9% for DNAJC3 | ~95% for single gene disorders |
| Turnaround Time | 3–4 Weeks | 6–10 Weeks |
| Cost (AED) | 2,800 | 5,500–8,000 |
| DHA Compliance | Full – DHA Licensed & PDPL Compliant | Variable |
Physician Insight & Safety Protocols
Message from Consultant Medical Genetics Lina Osama Zaki Quteineh (DHA License: 9294403)
As a DHA-licensed medical geneticist, I emphasize that this DNAJC3 test provides a high-confidence molecular diagnosis for the associated syndrome. However, results must be interpreted within the full clinical context, including family history and neurological assessment. A negative result does not exclude other genetic or acquired causes of ataxia, hearing loss, or diabetes. Pre- and post-test genetic counseling is mandatory under UAE regulations and is included in your package.
Advisory: Medication Safety
Do not discontinue any prescribed medication for ataxia, diabetes, or hearing loss without consulting your treating physician. This genetic test does not replace ongoing clinical management.
Exclusion Criteria
- Patients with acute illness or infection that may compromise sample integrity.
- Individuals unable to provide informed consent as per Federal Decree-Law No. 4 of 2016 on Medical Liability.
- Minors without legal guardian consent, as mandated by the same law.
Patient FAQ & Clinical Guidance
1. What does this DNAJC3 genetic test diagnose?
This test detects pathogenic variants in the DNAJC3 gene, confirming a rare autosomal recessive syndrome characterized by cerebellar ataxia, peripheral neuropathy, sensorineural hearing loss, and early-onset diabetes mellitus. Early diagnosis enables targeted diabetes management, audiological intervention, and genetic family counseling.
2. How is the sample collected and when will I receive results?
A certified phlebotomist visits your home in the UAE between 8 AM and 11 PM for VIP mobile phlebotomy (whole blood). Alternatively, you may submit extracted DNA or a dried blood spot on an FTA card via secure courier. Results are delivered within 3–4 weeks via encrypted portal and hard copy.
3. Is genetic counseling required before taking this test?
Yes, pre-test genetic counseling is mandatory under UAE law. Our DHA-licensed genetic counselor will review your family history, explain potential outcomes, and obtain informed consent. This service is included in the test package at no additional cost.
UAE Regulatory & Data Privacy Adherence
Our laboratory operates in full compliance with UAE healthcare regulations and data protection standards:
- Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) – genetic data is encrypted, access-controlled, and processed with the highest confidentiality.
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields – ensures secure digital handling of health records.
- Federal Decree-Law No. 4 of 2016 on Medical Liability – governs informed consent, clinical safety, and patient rights.
- ISO 9001:2015 Certification – Cert: INT/EGQ/2509DA/3139 (Quality Management for Medical Laboratories).
Clinical & Logistical Metadata
| Test Name | DNAJC3 Gene Full Sequencing (NGS) |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Whole Blood (peripheral) / Extracted DNA / Dried Blood Spot on FTA Card |
| Methodology Used | Next-Generation Sequencing (NGS) with Sanger Confirmation |
| ICD-10-CM Code | G11.9, E11.9, H90.5 |
| LOINC Code | 81303-8 |
| DHA Facility License & Laboratory Address | DHA License: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians