Test Price
2,800 AED✅ Home Collection Available
CSF1R Gene Leukoencephalopathy (Diffuse Hereditary with Spheroids) Genetic Test in UAE | 2800 AED
Executive Summary & Core Metrics
- ✔Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Certified Sequencing (Cert: INT/EGQ/2509DA/3139)
- ✔Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily 8 AM – 11 PM)
- ✔Clinical Guidance: Telephonic Post-Test Clinical Guidance for result interpretation with DHA-licensed Consultant Medical Genetics
- ✔Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731
Test Overview & Methodology
This advanced genetic test sequences the entire coding region of the CSF1R gene to confirm a molecular diagnosis of hereditary diffuse leukoencephalopathy with spheroids (HDLS/ALSP), an adult-onset progressive neurological disorder. The test is designed for patients with suggestive white matter changes on MRI, a positive family history, or undiagnosed adult leukodystrophies.
| Feature | Our CSF1R NGS Test | Closest Alternative (Single‑Gene Sanger) |
|---|---|---|
| Precision | >99.9% analytical sensitivity & specificity with whole‑gene coverage | Limited to exon‑by‑exon sequencing; may miss deep intronic variants |
| Methodology | Next‑Generation Sequencing (NGS) with copy number variant analysis and Sanger validation | Conventional Sanger sequencing – lower resolution for mosaicism and deletions |
| Turnaround Time | 3 to 4 weeks (comprehensive clinical report) | 4–6 weeks or longer for full gene coverage |
| Clinical Utility | Definitive diagnosis, familial variant testing, reproductive counselling | May require sequential single‑exon tests, delaying answers |
Physician Insight & Safety Protocols
“A positive CSF1R genetic result provides molecular confirmation of HDLS/ALSP, but clinical correlation with neuroimaging, neuropsychological assessment, and detailed family history is imperative. I strongly recommend that every patient undergo dedicated pre-test and post-test genetic counseling to fully comprehend the autosomal dominant inheritance pattern and its implications for at‑risk relatives. Never discontinue prescribed medications or abandon routine neurological follow‑up without first discussing your genetic report with your treating physician.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Medication Advisory
Do not discontinue any prescribed medication without consulting your doctor.
Always consult your treating physician before making any changes to your medication regimen, especially those related to neurological conditions.
Exclusion Criteria & Emergency Red Flags
- Exclusion Criteria: This test is not intended for asymptomatic individuals without a suggestive family history, nor for standalone screening in minors below 18 years without legally authorized consent.
- Emergency Red Flags: If you experience sudden neurological deterioration, new‑onset seizures, loss of consciousness, or acute confusion, seek immediate emergency medical care (call 998 in the UAE). Do not wait for genetic test results.
Patient FAQ & Clinical Guidance
1. What is the purpose of this CSF1R gene test?
This NGS test identifies pathogenic variants in the CSF1R gene that cause hereditary diffuse leukoencephalopathy with spheroids (HDLS/ALSP), enabling a definitive molecular diagnosis and guiding family risk assessment.
2. How long does it take to receive results?
Our laboratory delivers comprehensive reports within 3 to 4 weeks using advanced next‑generation sequencing technology, including variant interpretation and clinical correlation.
3. Is home sample collection available in the UAE?
Yes, our VIP mobile phlebotomy service covers all Emirates with ISO-certified cold‑chain transport; you can schedule a home or hotel collection by calling or WhatsApp +971 54 548 8731.
UAE Regulatory & Data Privacy Adherence
Data Protection & Compliance: All genetic data processing and storage fully comply with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Patient consent is obtained in strict accordance with Federal Decree-Law No. 4 of 2016 on Medical Liability. Results are shared only with the requesting physician and the patient through secure channels.
DHA Facility License Number: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE
Clinical & Logistical Metadata
| Test Name | CSF1R Gene Sequencing for Hereditary Diffuse Leukoencephalopathy with Spheroids |
| Price (AED) | 2800 |
| Turnaround Time | 3 to 4 weeks |
| Sample Type / Matrix | Peripheral whole blood (EDTA) |
| Methodology Used | Next-Generation Sequencing (NGS) with CNV analysis and Sanger validation |
| ICD-10-CM Code | G37.8 |
| LOINC Code | 94712-8 |
| DHA Facility License & Laboratory Address | DHA Facility License Number: 1143, Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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