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Test Price

2,800 AED

✅ Home Collection Available

ATXN10 (Ataxin-10) Gene Spinocerebellar Ataxia Type 10 Autosomal Dominant Genetic Test in UAE | 2,800 AED | DHA Licensed

Executive Summary & Core Metrics

Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015-certified processing (Cert: INT/EGQ/2509DA/3139).
Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily from 8 AM to 11 PM.
Clinical Guidance: Post-test telephonic clinical guidance in result interpretation by a DHA-licensed genetics specialist.
Insurance: Direct billing verification and pre-authorization assistance via WhatsApp +971 54 548 8731.

Test Overview & Methodology

The ATXN10 gene Next-Generation Sequencing (NGS) test detects the pathogenic pentanucleotide repeat expansion responsible for Spinocerebellar Ataxia Type 10 (SCA10), an autosomal dominant neurodegenerative disorder. This advanced genetic analysis provides patients and families with a definitive diagnostic answer regarding the cause of hereditary ataxia, enabling informed clinical management and family planning.

Feature Our Test (DHA-Licensed) Closest Alternative
Methodology Next-Generation Sequencing (NGS), full gene coverage Sanger sequencing or targeted repeat-primed PCR (limited to known expansion)
Diagnostic Precision >99.9% sensitivity for repeat expansion detection Variable; may miss atypical expansions or secondary variants
Turnaround Time 3–4 weeks Often 6–8 weeks
Home Collection VIP cold-chain home phlebotomy (8 AM–11 PM) May not be available or not ISO-cold-chain verified
Accreditation ISO 9001:2015, DHA-licensed facility (License 1143) Variable; may lack UAE-specific licensure

Physician Insight & Safety Protocols

Lina Osama Zaki Quteineh, Consultant Medical Genetics | DHA Registration ID: 9294403

"Genetic testing for SCA10 provides a pivotal molecular diagnosis, yet it must always be integrated within a comprehensive clinical and family history evaluation. I encourage patients to approach this test as one component of a thorough neurological assessment, supported by a multidisciplinary team that respects both medical and emotional needs."

Advisory Notice: Medication Continuity

Medication Warning

Do not discontinue any prescribed medication without consulting your treating physician. Abrupt changes can destabilise neurological function. This genetic test result does not replace the need for ongoing clinical management by your healthcare provider.

Exclusion Criteria & Emergency Red Flags

  • Exclusion: Predictive testing for minors (under 12 years) without legal guardian consent – strict compliance with Federal Decree-Law No. 4 of 2016 on Medical Liability.
  • Exclusion: Patients lacking clinical suspicion of hereditary ataxia or a confirmed family history of SCA10; non-indicated testing is not performed.
  • Exclusion: Inability to provide a blood sample (severe anaemia, extreme phobia) — discuss alternative sample types (extracted DNA, FTA card) with our team.
  • Emergency Red Flags: Sudden severe ataxia with confusion, loss of consciousness, acute stroke signs, or suspected toxic ingestion require immediate emergency evaluation — not a genetic test appointment.
  • Emergency Red Flags: Withdrawal symptoms from anti-epileptics or benzodiazepines mimicking ataxia — urgent physician review needed.

Patient FAQ & Clinical Guidance

1. What exactly does the ATXN10 Genetic Test detect, and how does it confirm Spinocerebellar Ataxia Type 10?

This test identifies the pathogenic pentanucleotide repeat expansion in the ATXN10 gene using high-throughput Next-Generation Sequencing, providing definitive molecular confirmation of SCA10 with over 99.9% sensitivity. The analysis specifically screens for abnormally expanded ATTCT repeats in intron 9, which cause neuronal dysfunction. A positive result confirms the diagnosis in symptomatic individuals and guides family planning decisions for autosomal dominant inheritance.

2. What sample types are accepted, and how is home collection arranged in the UAE?

We accept whole blood (3–5 mL in EDTA), extracted DNA, or a dried blood spot on an FTA card — all collected via VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily from 8 AM to 11 PM. To arrange, simply WhatsApp +971 54 548 8731 with your DHA-registered physician's referral; our logistics team coordinates a certified mobile phlebotomist who maintains ISO-certified cold chain from doorstep to lab, ensuring sample stability.

3. What legal protections exist for my genetic data under UAE law, and is this test endorsed by DHA?

Your genetic data is safeguarded under Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. This test is performed in a DHA-licensed facility (License 1143) compliant with all regulations. No genetic information is shared without explicit written consent, and results are delivered exclusively to the ordering physician and patient through encrypted channels. The laboratory holds ISO 9001:2015 certification, regularly audited for data integrity and clinical governance.

UAE Regulatory & Data Privacy Adherence

Data Protection & Regulatory Compliance

DNA Labs UAE operates under DHA Facility License Number 1143, strictly adhering to:

  • Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) — ensuring complete confidentiality and secure processing of your genetic and personal data.
  • Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields — governing the ethical use of digital health records and telemedicine.
  • Federal Decree-Law No. 4 of 2016 on Medical Liability — protecting patient safety and informed consent throughout the diagnostic process.

Your results are delivered via encrypted channels exclusively to you and your referring physician. No third-party access is permitted without explicit written consent.

Clinical & Logistical Metadata

Test Name ATXN10 (Ataxin-10) Gene Spinocerebellar Ataxia Type 10 Autosomal Dominant Genetic Test
Price (AED) 2,800 AED
Turnaround Time 3–4 weeks
Sample Type / Matrix Whole blood (3–5 mL in EDTA), extracted DNA, or dried blood spot (FTA card)
Methodology Used Next-Generation Sequencing (NGS) with full gene coverage including pentanucleotide repeat expansion analysis
ICD-10-CM Code G11.2
LOINC Code 21636-6
DHA Facility License & Laboratory Address DHA License: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE

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