Test Price
2,800 AED✅ Home Collection Available
ARX Gene Early Infantile Epileptic Encephalopathy Type 1 Genetic Test in UAE
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited NGS Sequencing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
- Clinical Guidance: Telephonic Post-Test Result Interpretation & Guidance from a DHA-licensed Consultant Medical Geneticist.
- Insurance: Direct Billing Verification & Pre-Approval Support via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The ARX gene test sequences the aristaless-related homeobox gene to diagnose Early Infantile Epileptic Encephalopathy Type 1 (EIEE1), a severe neonatal-onset seizure disorder characterised by infantile spasms, developmental delay, and intractable epilepsy. Our comprehensive NGS panel delivers full coding region coverage with copy number variant detection, enabling precise molecular diagnosis to guide targeted treatment and family counselling.
| Feature | Our ARX NGS Test | Closest Alternative (Conventional) |
|---|---|---|
| Methodology | High-depth Next-Generation Sequencing (NGS) with CNV detection | Sanger sequencing or limited gene panels |
| Diagnostic Sensitivity | 99.9% (ISO 9001:2015 validated) | 85–95% for known variants; may miss novel mutations and CNVs |
| Turnaround Time | 3 to 4 Weeks | 4 to 6 Weeks (manual interpretation) |
| Total Price | 2,800 AED (all-inclusive) | 3,500–5,000 AED (often excludes counselling) |
| Sample Options | Peripheral Whole Blood (EDTA), Extracted DNA, or FTA Card | Blood only |
| UAE Accreditation | DHA Facility License 1143; ISO 9001:2015 | Often overseas lab with uncertain DHA compliance |
Physician Insight & Safety Protocols
"A molecular diagnosis of ARX-related EIEE1 can dramatically alter the clinical trajectory by enabling early initiation of targeted antiseizure therapy and informed reproductive planning for families. However, the absence of an ARX mutation does not exclude other genetic epilepsies; correlation with electroclinical phenotyping remains essential for comprehensive patient management."
— Lina Osama Zaki Quteineh, Consultant Medical Genetics | DHA Registration ID: 9294403
Important Advisory
Do not discontinue or alter prescribed antiseizure medication without consulting the treating physician. Genetic test results should guide, not replace, clinical judgement in acute seizure management.
Exclusion Criteria & Emergency Red Flags
- Not indicated for asymptomatic individuals with no family history of EIEE1.
- For minors, mandatory written informed consent from a legal guardian per Federal Decree-Law No. 4 of 2016 on Medical Liability.
- If a child experiences a seizure lasting more than 5 minutes, breathing difficulty, or cyanosis, seek immediate emergency care at the nearest hospital.
- This test is not a substitute for acute neurological evaluation in a medical emergency.
Patient FAQ & Clinical Guidance
1. What is the ARX gene early infantile epileptic encephalopathy genetic test?
Our ARX gene test employs high-depth next-generation sequencing to detect pathogenic variants associated with Early Infantile Epileptic Encephalopathy Type 1. The assay analyses the entire coding region and conserved splice sites of the ARX gene, identifying point mutations, small insertions and deletions, and copy number variants, thereby providing a definitive molecular diagnosis when clinical suspicion is elevated.
2. How is the test performed and what sample is required?
A peripheral whole blood sample collected in an EDTA tube is the primary specimen, though extracted DNA or an FTA card blood spot are also accepted. Our licensed phlebotomist performs the draw at your home under strict temperature-controlled shipping conditions between 8 AM and 11 PM daily. The blood sample is transported via certified cold chain to our ISO-accredited laboratory for genomic analysis.
3. What is the turnaround time and total cost in the UAE?
The final clinical report, reviewed and signed by a DHA-licensed Consultant Medical Geneticist, is delivered within 3 to 4 weeks from sample receipt. The all-inclusive cost is 2,800 AED, covering pre-test genetic counselling, NGS sequencing, bioinformatic analysis, CNV detection, variant interpretation, and a comprehensive clinical report compliant with DHA diagnostic standards.
4. What does a positive ARX test result mean for my child?
A positive result confirms a pathogenic or likely pathogenic variant in the ARX gene, establishing the molecular diagnosis of EIEE1. This enables targeted seizure management, access to early intervention programmes, and accurate recurrence risk counselling for family planning. Your geneticist will discuss phenotype-genotype correlation, anticipated disease course, and available support services during the follow-up teleconsultation.
5. Does health insurance cover this genetic test in Dubai?
Coverage varies by insurance provider and policy type. Our insurance team performs direct billing verification and pre-approval support upon request via WhatsApp at +971 54 548 8731. Many comprehensive plans with genetic testing benefits provide partial or full coverage for diagnostically indicated molecular tests prescribed by a specialist.
UAE Regulatory & Data Privacy Adherence
Your genetic data is handled in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All genomic sequencing data is encrypted, access-controlled, and retained only for the period required for clinical reporting and quality assurance.
DNA Labs UAE maintains strict confidentiality protocols aligned with DHA standards for genetic information. No genetic data is shared with third parties without your explicit written consent, except as required by UAE law.
Clinical & Logistical Metadata
| Test Name | ARX Gene Early Infantile Epileptic Encephalopathy Type 1 Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type / Matrix | Peripheral Whole Blood (EDTA), Extracted DNA, or FTA Card |
| Methodology Used | High-Depth Next-Generation Sequencing (NGS) with CNV Detection |
| ICD-10-CM Code | G40.4 |
| LOINC Code | 81306-1 |
| DHA Facility License & Laboratory Address | DHA Facility License Number: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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