Test Price
2,800 AEDโ Home Collection Available
AR Gene Spinal & Bulbar Muscular Atrophy (SBMA) Genetic Test in UAE | 2,800 AED
Executive Summary & Core Metrics
- Diagnostic Accuracy: 99.9% sensitivity via ISO-certified next-generation sequencing processing.
- Premium Logistics: VIP mobile phlebotomy and temperature-controlled cold-chain home collection available daily from 8 AM to 11 PM.
- Clinical Guidance: Post-test telephone consultation with a DHA-licensed Consultant Medical Geneticist to interpret results.
- Insurance Verification: Direct coverage confirmation via WhatsApp at +971 54 548 8731.
Test Overview & Methodology
The AR gene NGS test analyzes the androgen receptor gene for CAG trinucleotide repeat expansions that cause Spinal and Bulbar Muscular Atrophy (SBMA), also known as Kennedy disease โ a rare X-linked motor neuron disorder. This next-generation sequencing assay delivers definitive genetic diagnosis with 99.9% precision, enabling timely clinical intervention, accurate prognostic counseling, and informed family planning decisions. The test detects expansions beyond the normal threshold of 35 repeats, with full coverage of the AR gene coding region to rule out concurrent pathogenic variants.
Clinical correlation with neurological examination, electromyography, and family history is essential for comprehensive patient management. A positive result confirms the presence of a pathogenic CAG repeat expansion and must be contextualized against symptom onset, disease progression, and bulbar involvement severity.
| Feature | Our Test | Closest Alternative |
|---|---|---|
| Methodology | Next-Generation Sequencing (NGS) โ Full AR Gene Coverage | Targeted Sanger sequencing for known expansions only |
| Analytical Precision | 99.9% Diagnostic Sensitivity | ~95% |
| Turnaround Time | 3 to 4 Weeks | 4 to 6 Weeks |
Physician Insight & Safety Protocols
โThe AR gene NGS test for SBMA provides a definitive molecular diagnosis that transforms clinical decision-making. Identifying the exact CAG repeat length allows clinicians to distinguish Kennedy disease from ALS and other motor neuron disorders, guide respiratory monitoring, and offer precise reproductive risk counseling. Our multidisciplinary team ensures every result is interpreted within the full context of the patientโs neurological status and family pedigree.โ
โ Lina Osama Zaki Quteineh, Consultant Medical Genetics (DHA Registration ID: 9294403)
Advisory & Precautions
Clinical Advisory
Patients experiencing rapidly progressive dysphagia, respiratory distress, or signs of aspiration pneumonia should seek immediate emergency care. This genetic test is designed for diagnostic confirmation and does not replace urgent clinical evaluation for acute neurological decompensation. Always consult your managing physician before altering any prescribed therapy.
Exclusion Criteria & Patient Eligibility
Eligibility Requirements
- Individuals under 18 years of age require documented consent from a legal guardian as mandated by Federal Decree-Law No. 4 of 2016 on Medical Liability.
- Patients in acute psychiatric crisis who cannot provide informed consent are excluded from testing until stabilization and capacity are confirmed by a licensed psychiatrist.
- Unauthorized third-party requests without verifiable legal authority (e.g., court order or power of attorney) will not be processed.
Patient FAQ & Clinical Guidance
1. What is the clinical utility of AR gene NGS testing for spinal bulbar muscular atrophy?
Answer: AR gene NGS testing confirms Kennedy disease diagnosis by detecting pathogenic CAG repeat expansions with 99.9% accuracy. It enables differentiation from other motor neuron disorders, guides reproductive counseling, and identifies asymptomatic carriers in affected families. Repeat length correlates with age of onset and disease severity, supporting personalized management planning.
2. How should I prepare for the test and is fasting required?
Answer: No fasting is required. The test requires a peripheral whole blood sample or a DNA specimen collected via FTA card following a pre-test genetic counseling session. Our VIP mobile phlebotomy team manages all logistics with ISO-certified temperature-controlled cold-chain transport, available daily from 8 AM to 11 PM.
3. Does health insurance cover this genetic test in the UAE?
Answer: Direct billing verification is available via WhatsApp at +971 54 548 8731; coverage depends on your policy. We coordinate with all major UAE insurers and provide detailed invoices for reimbursement claims. Pre-authorization is recommended for genetic testing under most comprehensive health plans.
UAE Regulatory & Data Privacy Adherence
Regulatory Compliance Framework
All genetic data generated through this test is handled in strict accordance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Patient samples are processed under ISO-certified protocols, archived securely, and anonymized or destroyed upon written request. Clinical consent procedures follow the requirements of Federal Decree-Law No. 4 of 2016 on Medical Liability, ensuring full transparency and patient autonomy throughout the testing pathway.
DNA Labs UAE operates under DHA Facility License Number 1143 and adheres to all Dubai Healthcare City Authority quality standards for genetic and molecular diagnostics.
Clinical & Logistical Metadata
| Test Name | AR Gene Spinal & Bulbar Muscular Atrophy (SBMA) Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type / Matrix | Peripheral Whole Blood or FTA Card |
| Methodology Used | Next-Generation Sequencing (NGS) โ Full AR Gene Coverage |
| ICD-10-CM Code | G12.2 |
| LOINC Code | 21636-6 |
| DHA Facility License & Laboratory Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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All reports reviewed by DHA-Certified physicians