Test Price
2,800 AED✅ Home Collection Available
LRPPRC Gene Sequencing (Leigh Syndrome, French-Canadian Type) – Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل جين LRPPRC لمتلازمة لي (النوع الفرنسي-الكندي) – التسلسل الجيني NGS في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Executive Summary (ملخص تنفيذي)
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing (ISO 9001:2015).
- Premium Logistics: Paid Hospital-Grade Home Collection via ISO Certified Cold-Chain Home Collection and VIP Mobile Phlebotomy, ensuring sample integrity.
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation provided by DHA-licensed specialists.
- Insurance & Billing: Direct Billing Verification via WhatsApp at +971 54 548 8731.
Overview
This advanced Next-Generation Sequencing (NGS) test analyzes the LRPPRC gene to precisely diagnose Leigh syndrome, French-Canadian type, offering 99.9% sensitivity and 100% target coverage. يُحلل هذا الاختبار المتقدم تسلسل الجين LRPPRC باستخدام تقنية الجيل التالي (NGS) لتشخيص دقيق لمتلازمة لي (النوع الفرنسي-الكندي) بحساسية 99.9% وتغطية كاملة للجين المستهدف.
| Feature | Our LRPPRC NGS Test | Whole Exome Sequencing (Alternative) |
|---|---|---|
| Precision | Targeted high-depth sequencing of LRPPRC gene with >99% analytical sensitivity and specificity | Broad exome coverage; lower read depth at LRPPRC locus may miss variants |
| Methodology | Illumina-based NGS with full gene sequencing and deletion/duplication analysis | Whole exome capture followed by NGS |
| Turnaround Time (TAT) | 3–4 Weeks | 6–8 Weeks |
| Cost | 2800 AED | 4500–5000 AED (estimated) |
Physician Insight & Safety Protocol
“As a DHA-licensed clinical neurologist, I emphasize that this genetic test provides critical diagnostic confirmation for Leigh syndrome, French-Canadian type, but must always be correlated with clinical presentation, neuroimaging, and biochemical markers. Genetic findings alone cannot replace comprehensive neurological evaluation.” – Dr. Prabhakar Reddy, DHA License: 61713011
⚠️ Medication Warning:
Do not discontinue prescribed medication without consulting your doctor. Genetic test results may guide therapy but should never prompt unsupervised changes to existing treatment.
Exclusion Criteria & Emergency Red Flags
- Patients with severe coagulopathy or platelet disorders precluding blood draw.
- Neonates with insufficient blood volume for standard venipuncture (alternative sample types may be accepted).
- Seek immediate emergency care if you or the patient experiences: acute respiratory distress, seizures, loss of consciousness, or rapid neurological deterioration—do not wait for test results.
Patient FAQ & Clinical Guidance
1. What is the LRPPRC gene test, and why is it needed?
Snippet: The LRPPRC gene test detects pathogenic variants causing Leigh syndrome, French-Canadian type, to confirm diagnosis and guide management.
This NGS-based assay screens for known and novel mutations in the LRPPRC gene with high accuracy, enabling early intervention and genetic counseling for affected families. The test is indicated for infants and children presenting with neurological regression, hypotonia, and typical MRI findings.
اختبار جين LRPPRC يكشف الطفرات المسببة لمتلازمة لي (النوع الفرنسي-الكندي) لتأكيد التشخيص وتوجيه العلاج والدعم الوراثي للعائلة. يُستخدم التسلسل الجيني من الجيل التالي لفحص التغيرات الجينية بدقة عالية، مما يسمح بالتدخل المبكر والاستشارة الوراثية.
2. How is the sample collected, and is home collection available?
Snippet: Our certified phlebotomists collect a small blood sample at your home via cold-chain transport, ensuring sample integrity and convenience.
We offer VIP home collection across the UAE from 8 AM to 11 PM, using ISO-certified cold-chain logistics. You may provide whole blood, extracted DNA, or a single drop of blood on an FTA card. The process is swift and minimally invasive.
يقوم فريقنا المعتمد بسحب عينة دم صغيرة في منزلك باستخدام سلسلة تبريد معتمدة لضمان سلامة العينة وراحتك. تتوفر خدمة الجمع المنزلي الممتازة من الساعة 8 صباحاً حتى 11 مساءً مع خيارات متعددة للعينة.
3. What do the results mean, and how long does it take?
Snippet: Results indicate the presence/absence of LRPPRC mutations, with turnaround time of 3–4 weeks, including genetic counselling.
A positive result confirms the diagnosis and allows for tailored management and family planning. A negative result reduces the likelihood of this specific genetic cause, but further clinical evaluation may be needed. We provide a comprehensive report and telephonic clinical guidance to interpret the findings.
تظهر النتائج وجود أو غياب طفرات جين LRPPRC، مع فترة إنجاز تتراوح بين 3–4 أسابيع تشمل الاستشارة الوراثية. النتيجة الإيجابية تؤكد التشخيص وتوجه الخطة العلاجية والوراثية، بينما تستوجب النتيجة السلبية تقييماً طبياً إضافياً.
Pre-Test Information & Genetic Counselling
Before sample collection, a clinical history review and genetic counselling session are required to draw a pedigree chart of family members affected by Leigh syndrome, French-Canadian type. This ensures appropriate interpretation and risk assessment.
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians