Test Price
2,800 AEDโ Home Collection Available
LMNA Gene CMT2B1 Genetic Test in UAE | 2800 AED | DHA Certified
Test Overview & Methodology
The LMNA Gene CMT2B1 Next-Generation Sequencing (NGS) Genetic Test provides comprehensive screening of the LMNA gene for pathogenic variants associated with autosomal recessive Charcot-Marie-Tooth disease type 2B1, a progressive axonal neuropathy. Using NGS technology, this assay achieves unparalleled coverage of coding regions and splice sites, enabling precise diagnosis, carrier detection, and informed reproductive planning.
| Feature | Our Test (NGS โ LMNA Full Gene) | Closest Alternative (Targeted Sanger / Panel) |
|---|---|---|
| Methodology | Next-Generation Sequencing of entire LMNA coding and splicing regions | Limited to known hotspots or subset of exons |
| Variant Detection | SNVs, Indels, CNVs, deep intronic variants | Misses rare/novel mutations and structural variants |
| Turnaround Time | 3 โ 4 Weeks | 4 โ 8 Weeks (often outsourced) |
| Clinical Sensitivity | >99.9% (for LMNA CMT2B1 mutations) | ~70โ85% |
| Price (AED) | 2800 | 1800โ2500 (often incomplete) |
Physician Insight & Safety Protocols
โAs a Consultant Medical Geneticist, I recognize the profound impact of an accurate molecular diagnosis for hereditary neuropathies. The LMNA NGS test offers comprehensive coverage for CMT2B1, providing families with definitive answers and guiding management. It is essential to correlate genetic findings with clinical and electrophysiological data; genetic results should not be the sole basis for treatment decisions.โ
โ Lina Osama Zaki Quteineh | Consultant Medical Genetics | DHA Registration ID: 9294403
Exclusion Criteria & Safety Red Flags
- Sample rejection: insufficient DNA yield, clotted blood sample, or FTA card with expired matrix.
- Post-test emergency: if you experience sudden worsening of neuropathy, foot drop, respiratory difficulty, or severe muscle atrophy, seek immediate medical attention.
- Not for stand-alone prenatal decision-making without invasive confirmatory testing and genetic counselling.
- Patients unable to provide informed consent (or legal guardian for minors) โ consent procedures comply with Federal Decree-Law No. 4 of 2016 on Medical Liability.
Patient FAQ & Clinical Guidance
1. What is the LMNA gene and why test for CMT2B1?
The LMNA gene encodes lamin A/C proteins crucial for nerve cell structure; mutations cause Charcot-Marie-Tooth disease type 2B1 detectable only through NGS sequencing.
2. How is the sample collected and what are the pre-requirements?
A simple blood draw or DNA extraction on an FTA card is performed after mandatory genetic counselling and a pedigree chart of affected relatives.
3. What is the turnaround time and how will I receive my results?
Results are available within 3 to 4 weeks, delivered via a secure online portal with optional telephonic clinical interpretation by a DHA-licensed medical geneticist.
UAE Regulatory & Data Privacy Adherence
All genetic testing and associated data handling at DNA Labs UAE strictly comply with:
- Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) - ensuring your genetic information is securely processed and stored.
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields - governing digital health data and telemedicine.
- Federal Decree-Law No. 4 of 2016 on Medical Liability - mandating informed consent and patient safety protocols.
Your data is encrypted, accessed only by authorized personnel, and never shared without explicit consent.
Clinical & Logistical Metadata
| Test Name | LMNA Gene CMT2B1 Genetic Test (NGS) |
| Price (AED) | 2,800 |
| Turnaround Time | 3 โ 4 Weeks |
| Sample Type / Matrix | Peripheral Whole Blood (EDTA) or FTA Card (Dried Blood Spots) |
| Methodology Used | Next-Generation Sequencing (NGS) โ Full gene coverage including coding regions and splice sites |
| ICD-10-CM Code | G60.0 (Hereditary motor and sensory neuropathy) |
| LOINC Code | 94849-5 (LMNA gene mutation analysis in Blood by NGS) |
| DHA Facility License & Address | License #1143 ยท Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE ยท DNA Labs UAE |
ุฏุนู ุซูุงุฆู ุงููุบุฉ ู ุชุงุญ
ุงูุชุญูู ู ู ุงูุชุบุทูุฉ ุงูุชุฃู ูููุฉ
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
ุชููู ุนู ุงูุชุฎู ูู. ุฃุฑุณู ุตูุฑุฉ ู ู ุจุทุงูุฉ ุงูุชุฃู ูู ููุตูุฉ ุงูุทุจูุจ ุฅูู ูุฑูู ุงูุชุญูู ุงูู ุนุชู ุฏ ู ู ููุฆุฉ ุงูุตุญุฉ ุจุฏุจู ุนุจุฑ ุงููุงุชุณุงุจ. ุงุญุตู ุนูู ุชุญุฏูุซ ุงูุญุงูุฉ ูู ุฏูุงุฆู.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians