Test Price
2,800 AED✅ Home Collection Available
TBX19 Gene Adrenocorticotropic Hormone Deficiency Genetic Test in UAE | 2800 AED | DHA Licensed
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection Available Daily 8 AM to 11 PM.
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
This NGS test sequences the entire TBX19 gene to detect pathogenic variants causing congenital isolated adrenocorticotropic hormone (ACTH) deficiency, a rare endocrine disorder. Delivered with 100% clinical-grade accuracy and DHA-compliant interpretation, it empowers early diagnosis and personalized management.
| Feature | Our NGS Test | Closest Alternative (Sanger Sequencing) |
|---|---|---|
| Precision | >99.9% sensitivity, full coding region coverage | Limited to selected exons; may miss deep intronic variants |
| Method | Next-Generation Sequencing (NGS) with ACMG interpretation | Bidirectional Sanger sequencing, lower throughput |
| Speed | 3-4 Weeks (expedited options available) | 4-6 Weeks |
Physician Insight & Safety Protocols
“Our comprehensive NGS analysis of the TBX19 gene is essential for confirming isolated ACTH deficiency. However, results must be correlated with clinical presentation and biochemical profiles. A negative finding does not exclude other pituitary or adrenal disorders. Always consult with a medical geneticist for personalized interpretation.” – Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Important Advisory
Do not discontinue prescribed medication without consulting your doctor. Genetic testing is a diagnostic aid; treatment decisions should be made by your healthcare provider.
Exclusion Criteria & Emergency Red Flags
- Acute adrenal crisis requires immediate emergency stabilization before genetic testing.
- Not for newborn screening of congenital adrenal hyperplasia (CAH); order 21-hydroxylase test if CAH suspected.
ER Red Flags:
- If you experience sudden severe vomiting, profound hypotension, or hypoglycemia, seek emergency care immediately.
Patient FAQ & Clinical Guidance
1. What is the TBX19 gene test and why is it needed?
The TBX19 genetic test detects mutations causing isolated ACTH deficiency through comprehensive NGS sequencing. It is recommended when clinical signs (low cortisol, low ACTH) and family history suggest congenital ACTH deficiency, enabling precise diagnosis and familial risk assessment.
2. How is the sample collected and is home collection available?
A simple blood draw (whole blood or FTA card) is collected via VIP home phlebotomy service between 8 AM – 11 PM. The sample is transported under strict cold-chain protocol to our ISO-certified laboratory, ensuring DNA integrity and result reliability.
3. How long do results take and what does the report include?
Results are delivered within 3–4 weeks and include a detailed ACMG‑classified variant interpretation with clinical correlation. The report indicates pathogenic, likely pathogenic, or variants of uncertain significance, alongside genetic counseling recommendations and follow-up guidance.
UAE Regulatory & Data Privacy Adherence
This genetic test is performed under the regulatory oversight of the Dubai Health Authority (DHA) and complies with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Patient confidentiality, consent, and data security are guaranteed. The laboratory adheres to ISO 15189 standards and DHA licensing requirements.
Clinical & Logistical Metadata
| Test Name | TBX19 Gene Adrenocorticotropic Hormone Deficiency Genetic Test (NGS) |
| Price (AED) | 2,800 |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Whole Blood or FTA Card |
| Methodology Used | Next-Generation Sequencing (NGS) |
| ICD-10-CM Code | E23.0 |
| LOINC Code | 94083-0 |
| DHA Facility License & Laboratory Address | DHA Facility License Number: 1143 Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE Corporate Lab Branding: DNA Labs UAE |
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Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians