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Test Price

2,800 AED

✅ Home Collection Available

SERPING1 Gene Hereditary Angioedema Genetic Test in UAE | 2800 AED | DHA Licensed

Executive Summary & Core Metrics

  • Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Certified Processing.
  • Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily from 8 AM to 11 PM.
  • Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation by DHA-licensed specialists.
  • Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.

Test Overview & Methodology

The SERPING1 Genetic Test uses next-generation sequencing (NGS) technology to sequence the entire SERPING1 gene, identifying pathogenic mutations responsible for hereditary angioedema (HAE) types I and II. This test is essential for accurate diagnosis, family screening, and personalized treatment planning under UAE clinical guidelines.

Feature Our Test Closest Alternative
Method High-coverage NGS (all exons, splice sites) Sanger sequencing of selected exons
Diagnostic Precision 99.9% analytical sensitivity/specificity ~97% (misses deep intronic variants)
Turnaround Time 3–4 Weeks 6–8 Weeks

Physician Insight & Safety Protocols

“As a Consultant Medical Genetics, I emphasize that this genetic test provides definitive diagnosis for hereditary angioedema, but must be interpreted alongside clinical symptoms and family history. Never stop your current medications without medical advice; acute attacks require immediate emergency care. Your result empowers a tailored management plan to prevent life-threatening swelling.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics | DHA Registration ID: 9294403

Advisory Notice

Important Medication Warning

Do not discontinue prescribed medications without consulting your doctor. This test is for diagnostic and monitoring purposes only; it does not replace ongoing treatment or emergency intervention.

Exclusion Criteria & Red Flags

  • Patients currently experiencing acute angioedema attack with airway compromise must seek emergency care, not genetic testing.
  • Minors require parental consent and genetic counseling per Federal Decree-Law No. 4 of 2016 on Medical Liability.
  • This test is not suitable for prenatal diagnosis in acute settings.
  • ER Red Flag: If you develop sudden throat swelling, difficulty breathing, or severe abdominal pain, call 998 immediately.

Patient FAQ & Clinical Guidance

1. What is the SERPING1 gene test and how does it work?

This test uses next-generation sequencing to detect SERPING1 mutations causing hereditary angioedema types I and II. It analyzes all coding regions of the gene from a simple blood sample, providing definitive molecular diagnosis.

2. What sample is required and how is the process managed?

Home-collected blood samples allow full SERPING1 gene sequencing using high-coverage next-generation sequencing platform. Our DHA-certified phlebotomists provide VIP home collection with cold-chain transport to our ISO lab.

3. What do the results mean for my health and family?

A positive result confirms hereditary angioedema and guides C1 inhibitor therapy; a negative result requires clinical correlation. Genetic counseling will explain inheritance patterns and familial implications, supporting proactive health decisions.

UAE Regulatory & Data Privacy Adherence

This service adheres to Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All data handling and disclosure comply with the highest standards of confidentiality and security. Patient consent is obtained per Federal Decree-Law No. 4 of 2016 on Medical Liability.

Clinical & Logistical Metadata

Test Name SERPING1 Gene Hereditary Angioedema Genetic Test
Price (AED) 2,800
Turnaround Time 3–4 Weeks
Sample Type / Matrix Peripheral whole blood (3–5 mL in EDTA tube) or extracted DNA
Methodology Used Next-Generation Sequencing (NGS) of all coding exons and flanking splice sites
ICD-10-CM Code D84.1
LOINC Code 82753-8
DHA Facility License & Laboratory Address License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE

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