Test Price
2,800 AED✅ Home Collection Available
SLC52A1 Gene Riboflavin Deficiency Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل جين SLC52A1 لنقص الريبوفلافين بتقنية التسلسل الجيني المتقدم (NGS) في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Clinical Overview & Test Positioning
The SLC52A1 NGS test sequences the entire coding region of the riboflavin transporter gene, detecting single‑nucleotide variants, small insertions/deletions, and copy‑number changes linked to infant‑onset neurological decline. يُعد هذا الفحص الجيني الشامل أداة أساسية لتأكيد التشخيص واكتشاف حاملي الطفرة وتقديم المشورة الوراثية الدقيقة.
| Feature | Our Test (NGS) | Traditional Sanger Sequencing | Whole Exome Sequencing (WES) |
|---|---|---|---|
| Target Coverage | Complete SLC52A1 gene (exons, splice sites) | Selected exons only | ~20,000 genes (untargeted) |
| Detection Sensitivity | 99.9% (validated analytical sensitivity) | ~95% (limited to sequenced regions) | ~90% (variable coverage) |
| Turnaround Time | 3–4 weeks | 2–3 weeks | 4–8 weeks |
| Clinical Report | ACMG guideline‑based variant classification with carrier status | Basic variant listing | Broad, often incidental findings |
| Price (AED) | 2800 | ~2000 | ~4000 |
🩺Physician Insight & Urgent Safety Advisory
“This genetic test confirms a treatable neurometabolic disorder, but a negative result does not exclude biochemical riboflavin deficiency; always correlate with plasma riboflavin levels, acylcarnitine profile, and neurological exam. Early riboflavin supplementation can be life‑saving, so clinical judgment must guide treatment before results arrive.”
— Dr. PRABHAKAR REDDY, DHA License 61713011, Consultant Medical Geneticist
⚠ Medication Warning
Do not discontinue prescribed medication or supplements without consulting your doctor. Riboflavin supplementation should start only under specialist supervision, especially in infants with suspected acute neurological deterioration.
Safety Exclusion Criteria & ER Red Flags
- Exclusion: Acute severe illness requiring immediate ICU admission, inability to provide informed consent (guardian required for minors per CDS Law 2026), non‑UAE residents without valid Emirates ID.
- ER Red Flags – seek emergency care immediately: Sudden vision loss, respiratory distress, stridor, profound hypotonia with swallowing difficulty, or loss of consciousness.
- Genetic counselling with a certified geneticist (pedigree charting) is mandatory before sample collection.
Patient Frequently Asked Questions
1. What exactly does the SLC52A1 NGS test detect?
This targeted genetic test detects pathogenic variants in the SLC52A1 gene causing riboflavin transporter deficiency type 1. It sequences all exons and adjacent intronic regions using next‑generation sequencing with a validated sensitivity of 99.9%, enabling precise carrier screening and diagnostic confirmation even before symptoms fully manifest.
السؤال: ما الذي يكشفه تحليل جين SLC52A1 بتقنية NGS؟
الإجابة: يكشف هذا الاختبار الجيني المستهدف الطفرات المسببة لمرض نقص ناقل الريبوفلافين من النوع الأول بحساسية تبلغ 99.9%، مما يتيح التشخيص المبكر واكتشاف الحاملين.
2. Why should I choose this in the UAE?
Our DHA‑licensed lab offers ISO‑certified NGS analysis achieving 99.9% sensitivity for accurate carrier screening and diagnosis. We integrate genetic counselling, home blood collection, and insurance verification—all compliant with UAE PDPL, Federal Decree‑Law No. 41 of 2024, and DHA genetic testing regulations.
السؤال: لماذا أختار هذا الفحص في الإمارات؟
الإجابة: نوفر تحليلاً جينياً معتمداً من هيئة الصحة بدبي بشهادة ISO 9001:2015 وبدقة 99.9%، مع استشارات وراثية وسحب منزلي للعينات وتحصيل مباشر للتأمين.
3. How is the sample collected and when will I receive results?
Our home collection provides a blood or DNA sample with results delivered within 3–4 weeks. A certified phlebotomist arrives at your preferred time (8 AM–11 PM) to draw blood or collect a DNA FTA card; the sample is transported under validated cold‑chain conditions to our ISO‑accredited laboratory for NGS sequencing and interpretation.
السؤال: كيف يتم جمع العينة ومتى أحصل على النتائج؟
الإجابة: يوفر فريقنا الطبي خدمة سحب الدم أو عينة الحمض النووي في المنزل، وتصدر النتائج خلال 3 إلى 4 أسابيع بعد الفحص المختبري المعتمد.
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توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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ISMS 27001:2022
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All reports reviewed by DHA-Certified physicians