Test Price
2,800 AED✅ Home Collection Available
HADHA Gene Sequencing Test (LCHAD Deficiency) in UAE | 2 800 AED | 2026 DHA Guidelines
تحليل جين HADHA لكشف نقص إنزيم الهيدروكسي أسيل-المرافق أ الطويل السلسلة (LCHAD) في الإمارات | 2 800 درهم | معتمد من هيئة الصحة بدبي
Executive Summary
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited NGS Laboratory.
- Premium Logistics: Hospital-Grade Home Collection (8 AM–11 PM) with ISO-Certified Cold Chain – Blood, DNA, or FTA Card.
- Clinical Guidance: Complimentary telephonic post‑test result interpretation by DHA‑licensed clinical coordinators.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
ملخص تنفيذي
- حساسية تشخيصية 99.9% عبر مختبر معتمد ISO 9001:2015 لتقنية التسلسل الجيني من الجيل التالي.
- خدمة سحب منزلي بمعايير المستشفيات مع سلسلة تبريد معتمدة – دم كامل، DNA مستخلص، أو بطاقة FTA.
- استشارة هاتفية مجانية بعد الفحص لتفسير النتائج من قِبل منسقين سريريين مرخصين من هيئة الصحة بدبي.
- تحقق مباشر من تغطية التأمين عبر واتساب +971545488731.
Overview
The HADHA Gene Sequencing Test detects pathogenic variants in the HADHA gene responsible for Long‑chain 3‑hydroxyacyl‑CoA dehydrogenase (LCHAD) deficiency, a rare autosomal recessive disorder of mitochondrial fatty acid beta‑oxidation. This advanced Next‑Generation Sequencing (NGS) analysis provides comprehensive coverage of all coding exons, splice sites, and copy number variations, enabling definitive diagnosis and carrier screening. يكشف تحليل جين HADHA الطفرات المسببة لنقص إنزيم الهيدروكسي أسيل-المرافق أ الطويل السلسلة، وهو اعتلال وراثي جسمي متنحٍ في أكسدة الأحماض الدهنية.
| Feature | Our Test (HADHA NGS) | Closest Alternative (Sanger / Enzyme Assay) |
|---|---|---|
| Technology | Next‑Generation Sequencing (full gene) | Single‑gene Sanger sequencing or fibroblast enzyme assay |
| Diagnostic Sensitivity | >99.9% for SNVs, indels, and CNVs | ~85–90% if only common mutations tested |
| Turnaround Time | 3–4 Weeks | 6–8 Weeks (enzyme assay) / 3–5 Weeks (Sanger) |
| Cost | 2 800 AED | 2 500–3 500 AED |
Physician Insight & Safety Protocol
“As a clinician, I remind every patient that genetic results must be correlated with clinical presentation and family history. A positive HADHA mutation confirms the biochemical diagnosis and guides dietary management, emergency protocols, and cascade screening. A negative result does not exclude all metabolic disorders – follow your metabolic specialist’s advice. Please never stop prescribed medications or dietary regimens without discussing with your doctor.”
– Dr. PRABHAKAR REDDY, DHA License: 61713011
MEDICATION WARNING
Do not discontinue any prescribed medication, including medium‑chain triglyceride (MCT) oil or carnitine supplements, without explicit consultation of your treating physician.
Exclusion Criteria & Emergency Red Flags
- Exclusion: If whole blood is the only sample available, recent allogeneic blood transfusion (<2 weeks) may interfere with DNA integrity – use a buccal swab or FTA card as an alternative.
- Exclusion: Bone marrow transplant recipients may have chimeric DNA; a pre‑transplant sample or alternative tissue is recommended.
- Red Flag Symptoms – Seek Emergency Care: Vomiting, extreme lethargy, hypoglycemia, seizures, or sudden unresponsiveness, especially during fasting or illness; these may indicate a metabolic crisis.
Patient FAQ & Clinical Guidance
1. What does the HADHA gene sequencing test detect, and who should consider it?
This NGS test detects nearly all single nucleotide variants, insertions/deletions, and copy number changes in the HADHA gene, providing definitive diagnosis for LCHAD deficiency in symptomatic infants or confirmation in individuals with abnormal acylcarnitine profiles.
يكشف هذا الاختبار الطفرات الجينية في جين HADHA ويُستطب للأطفال الذين يُظهرون أعراضاً استقلابية أو عند وجود شك كيميائي حيوي في فحص حديثي الولادة.
2. How is the sample collected, and does home collection meet UAE safety standards?
A DHA‑registered phlebotomist collects blood using ISO‑certified cold‑chain protocols; you may also provide a painless finger‑prick drop on an FTA card or a saliva sample, all fully compliant with UAE infection control and PDPL data privacy laws.
تُجرى عملية السحب المنزلي بواسطة ممرض مرخص من هيئة الصحة بدبي مع الالتزام بمعايير التعقيم وسلسلة التبريد، أو باستخدام عينة دم على بطاقة FTA.
3. How long do results take, and will insurance cover the cost?
Final reports are delivered in 3–4 weeks through a secure patient portal; we verify your insurance coverage directly via WhatsApp at +971 54 548 8731 and offer self‑pay plans of 2 800 AED inclusive of pre‑test genetic counselling.
تُصدر النتائج خلال ثلاثة إلى أربعة أسابيع عبر بوابة إلكترونية آمنة؛ نتحقق من تغطية التأمين مسبقاً عبر واتساب 545488731 (971+).
Pre‑Test Requirements
- Provide a detailed clinical history of the patient who is undergoing the HADHA gene test.
- A mandatory pre‑ genetic counselling session (in‑person or telehealth) to draw a pedigree chart of family members affected with Long‑chain 3‑hydroxyacyl‑CoA dehydrogenase deficiency.
- No fasting is required; however, inform the laboratory if the patient has had a blood transfusion or bone marrow transplant in the preceding two weeks.
- Accepted samples: Whole Blood (EDTA), Extracted DNA, or One drop of blood on an FTA Card.
This service complies with UAE Federal Decree‑Law No. 41 of 2024 (Art. 87), the Clinical Data Standards Law 2026 (minors), and the UAE Personal Data Protection Law (PDPL). All genetic data is processed in an ISO 9001:2015‑certified facility (Cert: INT/EGQ/2509DA/3139) under DHA facility license 9834453.
For support or insurance verification, contact +971 54 548 8731 (WhatsApp).
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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All reports reviewed by DHA-Certified physicians