Test Price
2,800 AED✅ Home Collection Available
IDH2 Gene D‑2‑Hydroxyglutaric Aciduria Type 2 Genetic Test in UAE | 2,800 AED | 2026 DHA Guidelines
تحليل جين IDH2 لمرض حمض الهيدروكسي غلوتاريك من النوع الثاني في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO‑Accredited NGS Processing.
Premium Logistics: Paid Hospital‑Grade Home Collection via ISO‑Certified Cold‑Chain & VIP Mobile Phlebotomy.
Clinical Guidance: Telephonic Post‑Test Clinical Guidance in result interpretation by DHA‑qualified genetic counsellors.
Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
دقة تشخيصية بنسبة 99.9% عبر مختبر معتمد وفقًا لمعايير ISO 9001. تشمل الخدمة سحبًا منزليًا مبردًا وفقًا لبروتوكول سلسلة التبريد، وتوجيهًا سريريًا هاتفيًا بعد الفحص.
Overview
The IDH2 Gene NGS Test detects pathogenic variants underlying D‑2‑hydroxyglutaric aciduria type 2, a rare neurometabolic disorder, using comprehensive next‑generation sequencing with 99.9% sensitivity. يوفر هذا الفحص الجيني الدقيق تشخيصًا مبكرًا لاضطراب استقلابي نادر، مما يساعد الأطباء على إدارة الحالة واتخاذ القرارات العلاجية المناسبة.
| Feature | Our Test (NGS Full‑Gene Analysis) | Closest Alternative (Biochemical / Targeted Single‑Gene) |
|---|---|---|
| Precision | 99.9% sensitivity; detects all mutation types (SNVs, indels, CNVs) | Limited to known hotspots; misses rare variants |
| Methodology | NGS (Next‑Generation Sequencing) with full gene coverage | Sanger sequencing of selected exons or urinary organic acid analysis |
| Turnaround Time | 3 to 4 Weeks from sample receipt | 4–6 Weeks for Sanger; 2–3 Weeks for metabolite assay (less specific) |
| Diagnostic Utility | Definitive molecular diagnosis, carrier testing, and family screening | Only biochemical suspicion; cannot distinguish all types |
Physician Insight & Safety Protocol
“Genetic results are just one piece of the clinical puzzle. I always urge patients and their physicians to interpret these findings alongside a thorough metabolic workup and family history. A negative NGS panel does not exclude all genetic etiologies, and a variant of uncertain significance requires expert correlation before any treatment change.”
— Dr. Prabhakar Reddy, DHA License No. 61713011
⚕️ Medication Warning: Do not discontinue any prescribed medication or start new supplements without consulting your treating physician. This test does not replace emergency clinical assessment.
Exclusion Criteria & Emergency Red Flags
- Exclusion Criteria: Inadequate sample (haemolysed, clotted, or insufficient DNA); inability to obtain informed consent. Minors: Per UAE CDS Law 2026, genetic testing of minors requires documented parental consent and clinical justification.
- ER Red Flags: If the patient experiences acute vomiting, lethargy, hypotonia, seizures, or loss of consciousness — suspend all non‑emergent testing and seek immediate emergency medical care. Do not wait for test results.
Patient FAQ & Clinical Guidance
1. What is the IDH2 gene test and why is it needed?
The IDH2 gene detects mutations causing D‑2‑hydroxyglutaric aciduria type 2, a rare neurometabolic disorder. This NGS‑based analysis reads the entire coding region of the IDH2 gene to identify pathogenic variants linked to the condition. It is recommended for individuals with clinical signs such as developmental delay, epilepsy, or abnormal brain MRI findings suggestive of the disease, as well as for at‑risk family members seeking carrier screening.
يكشف اختبار جين IDH2 الطفرات المسببة لمرض حمض الهيدروكسي غلوتاريك من النوع الثاني، وهو اضطراب استقلابي نادر. يُستخدم التسلسل الجيني الكامل (NGS) لقراءة كامل المناطق المشفرة للجين، وتحديد المتغيرات المرضية المرتبطة بالحالة.
2. How is the sample collected and is the procedure safe?
A home blood draw or cheek swab collects DNA for NGS testing with 99.9% accuracy. A certified phlebotomist arrives with a sterile, single‑use kit, performs the venipuncture or buccal swab, and prepares the DNA extraction card or EDTA tube. The sample is transported in an ISO‑certified cold‑chain transporter. The process is painless for most people, and safety protocols meet all DHA and MOHAP standards.
يتم جمع العينة بسحب دم منزلي أو بمسحة من الخد، بواسطة ممرض معتمد، مع اتباع بروتوكول سلسلة تبريد صارم. الإجراء آمن وسريع ويتوافق مع معايير هيئة الصحة بدبي ووزارة الصحة.
3. How long do the results take and what happens after?
Results are typically reported within 3 to 4 weeks after the laboratory receives your sample. Once ready, a board‑certified genetic counsellor contacts you for a confidential telephone consultation to explain the report, discuss implications, and recommend any necessary follow‑up. You may also share the results directly with your referring physician.
تظهر النتائج عادةً خلال 3 إلى 4 أسابيع من استلام المختبر للعينة. يتواصل معك مستشار وراثي معتمد لتفسير التقرير وتقديم التوجيه الطبي اللازم.
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توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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